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Symptoms of Type 2 Diabetes
Symptoms Of Type 2 Diabetes Creative Commons
https://youtu.be/d8fBlTgn1_U
This is always a surprising situation for most people around, who just go for regular
check up to the doctor and end up knowing that they are suffering from one of the…
https://youtu.be/d8fBlTgn1_U
This is always a surprising situation for most people around, who just go for regular
check up to the doctor and end up knowing that they are suffering from one of the…
Cataract Explained from A to Z
This video was created for the contest " anatomy by students, international contest"
Category 5. ENT, ophthalmology, General Practice
This video by Hershko Sarah is licensed under the Creative Commons Attribution ShareAlike 4.0 International…
Category 5. ENT, ophthalmology, General Practice
This video by Hershko Sarah is licensed under the Creative Commons Attribution ShareAlike 4.0 International…
Introduction to The Anatomy of The Heart
Introduction to the anatomy of the heart, with explanation of the pericardium, myocardium, and endocardium.
Psych9B. Psychology Fundamentals. Lecture 1:
UCI Psych 9B: Psych Fundamentals (Fall 2015)
Lec 01. Psych Fundamentals
View the complete course:
http://ocw.uci.edu/courses/psych_9bpsy_beh_11b_psychology_fundamentals.html
Instructor: Mark Steyvers, Ph.D.
License: Creative Commons CC-BY-SA
Terms…
Lec 01. Psych Fundamentals
View the complete course:
http://ocw.uci.edu/courses/psych_9bpsy_beh_11b_psychology_fundamentals.html
Instructor: Mark Steyvers, Ph.D.
License: Creative Commons CC-BY-SA
Terms…
Psych9B. Psychology Fundamentals. Lecture 2:
UCI Psych 9B: Psych Fundamentals (Fall 2015)
Lec 02. Psych Fundamentals
View the complete course:
http://ocw.uci.edu/courses/psych_9bpsy_beh_11b_psychology_fundamentals.html
Instructor: Mark Steyvers, Ph.D.
License: Creative Commons CC-BY-SA
Terms…
Lec 02. Psych Fundamentals
View the complete course:
http://ocw.uci.edu/courses/psych_9bpsy_beh_11b_psychology_fundamentals.html
Instructor: Mark Steyvers, Ph.D.
License: Creative Commons CC-BY-SA
Terms…
Ketogenesis, Diabetes, and Starvation
MIT 5.07SC Biological Chemistry, Fall 2013
View the complete course: http://ocw.mit.edu/5-07SCF13
Instructor: John Essigmann
In this video, Professor Essigmann explores ketone bodies – what they are, how they are made, and how they are used in…
View the complete course: http://ocw.mit.edu/5-07SCF13
Instructor: John Essigmann
In this video, Professor Essigmann explores ketone bodies – what they are, how they are made, and how they are used in…
Diabetes in Pregnancy
Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT related content. These videos do not provide medical advice and are for informational…
How Not to Die from Heart Disease
Lifestyle approaches aren’t just safer and cheaper. They can work better, because you’re treating the actual cause of the disease.
Input by Sofia Nelly
Subscribe to Dr. Greger’s free nutrition newsletter at…
Input by Sofia Nelly
Subscribe to Dr. Greger’s free nutrition newsletter at…
Hypotension
Hypotension is low blood pressure, especially in the arteries of the systemic circulation. Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. Hypotension is generally considered if systolic…
Creative Accounting
Creative accounting is a euphemism referring to accounting practices that may follow the letter of the rules of standard accounting practices, but deviate from the spirit of those rules. They are characterized by excessive complication and the use of…
12 All Natural Toothache
In the past, before modern dentistry, people use to treat a tooth pain naturally because they had no other option.
Nowadays, modern medicine has its own solutions, but there still several natural toothache remedies that people use just to avoid the…
Nowadays, modern medicine has its own solutions, but there still several natural toothache remedies that people use just to avoid the…
The Normal Electrocardiogram
A lecture on electrocardiograms by Dr. Kim Eagle, M.D. This lecture was taught as a part of the University of Michigan Medical School's M2 - Cardiovascular Sequence.
View the course…
View the course…
Chronic Coronary Artery Disease
A lecture on chronic coronary artery disease by Dr. Kim Eagle, M.D. This lecture was taught as a part of the University of Michigan Medical School's M2 - Cardiovascular Sequence
View the course…
View the course…
Acute Coronary Syndromes
A lecture on acute coronary syndromes by Dr. Kim Eagle, M.D. This lecture was taught as a part of the University of Michigan Medical School's M2 - Cardiovascular Sequence
View the course…
View the course…
The Evaluation of Chest Pain
A lecture on evaluating a patient with chest pain by Dr. Kim Eagle, M.D. This lecture was taught as a part of the University of Michigan Medical School's M2 - Cardiovascular Sequence
View the course…
View the course…
Removal of Carious Lesion
Includes a display of instruments necessary for caries removal, a discussion of the steps and criteria involved and demonstration of a complete removal of a carious lesion. Orig. air date: JAN 8 74
This is part of the Open.Michigan collection at:…
This is part of the Open.Michigan collection at:…
Local Anesthetic Injection Techniques
Demonstrates on the skull and on a patient, various injection techniques. It also describes the basic dental chair position for injections. Orig. air date: NOV 8 74
This is part of the Open.Michigan collection at:
http://open.umich.edu/education
This is part of the Open.Michigan collection at:
http://open.umich.edu/education
Scaling and Root Planing: Part II Mandibular Teeth
Procedures for scaling and root planing the mandibular teeth.
This is part of the Open.Michigan collection at:
http://open.umich.edu/education
This is part of the Open.Michigan collection at:
http://open.umich.edu/education
Interproximal Radiography
This is part of the Open.Michigan collection at:
http://open.umich.edu/education
http://open.umich.edu/education
Geotechnical Engineering
After viewing previous lectures on seismicity you have basic understanding of earthquakes. Let’s have a further look at what this means for buildings and its foundations. This introduction lecture on geotechnical engineering by Carlos Merino…
Frontiers in Cardiovascular Care
This sequence provides a comprehensive introduction to diseases of the cardiovascular system, how they present, how they are diagnosed, how they are prevented, and how they are treated. Students learn to identify the integral links between anatomy,…
Physiology/ Pathophysiology of Coronary Blood Flow
Myocardial Ischemia
Supply
Demand
Coronary Flow Reserve
Determinants of Coronary Blood Flow
Neural (autonomic) Mechanisms
Endothelial Factors (Mechanisms)
NOS, NO and ADMA
Supply
Demand
Coronary Flow Reserve
Determinants of Coronary Blood Flow
Neural (autonomic) Mechanisms
Endothelial Factors (Mechanisms)
NOS, NO and ADMA
Bone Marrow Pathology
In this book we have set out to provide a practical guide to bone marrow diagnosis, based on an integrated assessment of peripheral blood and bone marrow aspirate films, trephine biopsy sections and various supplementary investigations. We believe…
Hemoglobinopathies Part 1
A lecture on Hemoglobinopathies by Dr. David Ginsburg, M.D. This lecture was taught as a part of the University of Michigan Medical School's M1 - Patients and Populations Sequence. View the course…
Hemoglobinopathies Part 2
A lecture on Hemoglobinopathies by Dr. David Ginsburg, M.D. This lecture was taught as a part of the University of Michigan Medical School's M1 - Patients and Populations Sequence. View the course…
Surgical Excision of a Multi-Lobular, Recurrent, Bartholin Duct Cyst
Warning: Viewer discretion is advised, this medical content is graphic and may not be suitable for all viewers. This surgical video describes the etiology, diagnosis, and management of uncomplicated Bartholin duct cysts. The video provides specific…
Circulatory Derangements I
A lecture on Circulatory Derangements by Dr. Gerald Abrams, M.D. This lecture was taught as a part of the University of Michigan Medical School's M1 - Cardiovascular and Respiratory Sequence.
View the course…
View the course…
Circulatory Derangements II
A lecture on Circulatory Derangements by Dr. Gerald Abrams, M.D. This lecture was taught as a part of the University of Michigan Medical School's M1 - Cardiovascular and Respiratory Sequence.
View the course…
View the course…
AP Environmental Science
The earth's biogeochemical systems involve complex, dynamic processes that depend upon many factors. The three main factors upon which life on the earth depends.
Anatomy & Physiology
Welcome to Human Anatomy and Physiology, an OpenStax College resource. We created this textbook with several goals
in mind: accessibility, customization, and student engagement—helping students reach high levels of academic scholarship.
Instructors…
in mind: accessibility, customization, and student engagement—helping students reach high levels of academic scholarship.
Instructors…
Testosterone
Created by Vishal Punwani.
Watch the next lesson: https://www.khanacademy.org/test-prep/nclex-rn/rn-reproductive-system-physiology/rn-reproductive-system/v/basics-of-egg-development?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn
Missed the…
Watch the next lesson: https://www.khanacademy.org/test-prep/nclex-rn/rn-reproductive-system-physiology/rn-reproductive-system/v/basics-of-egg-development?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn
Missed the…
The Ovarian Cycle
Created by Vishal Punwani.
Watch the next lesson: https://www.khanacademy.org/test-prep/nclex-rn/rn-reproductive-system-physiology/rn-reproductive-system/v/meet-the-placenta?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn
Missed the…
Watch the next lesson: https://www.khanacademy.org/test-prep/nclex-rn/rn-reproductive-system-physiology/rn-reproductive-system/v/meet-the-placenta?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn
Missed the…
Reproductive system physiology
Created by Vishal Punwani.
Watch the next lesson:…
Watch the next lesson:…
How to Remove Surgical Staples :)
www.EmpoweRN.com
Hi Guys!
Thank you so much for watching this channel :)
Here is just a quick & simple nursing skill, that I really hope you enjoy!
I appreciate all of your comments, likes & shares so much!!
Really looking forward to growing…
Hi Guys!
Thank you so much for watching this channel :)
Here is just a quick & simple nursing skill, that I really hope you enjoy!
I appreciate all of your comments, likes & shares so much!!
Really looking forward to growing…
G Protein Coupled Receptors Nervous system physiology
Video ini menjelaskan tentang G-protein coupled receptor (reseptor G-protein bergandengan) yang juga biasa dikenal dengan GPCRs.
G-protein coupled receptors hanya bisa ditemukan pada eukariot dan GPCRs adalah kelas yang terbesar dari semua reseptor…
G-protein coupled receptors hanya bisa ditemukan pada eukariot dan GPCRs adalah kelas yang terbesar dari semua reseptor…
Pain Temperature
Pain Temperature
BY : UPT Perpustakaan Universitas Syiah Kuala
UKM Literasi Unsyiah
BY : UPT Perpustakaan Universitas Syiah Kuala
UKM Literasi Unsyiah
Fundamentals of Electrical Engineering I
The text focuses on the creation, manipulation, transmission, and reception of information by electronic means. Contents: 1) Introduction. 2) Signals and Systems. 3) Analog Signal Processing. 4) Frequency Domain. 5) Digital Signal Processing. 6)…
Introduction to Physical Electronics
An introduction to solid state device including field effect and bipolar transistors. Properties of transmission lines and propagating E&M waves.
Accounting Principles: A Business Perspective,
Financial Accounting (Chapters 1 – 8)
Preface from the eight edition:
Philosophy and purpose
Imagine that you have graduated from college without taking an accounting course. You are
employed by a company as a sales person, and you eventually become the sales manager of a…
Philosophy and purpose
Imagine that you have graduated from college without taking an accounting course. You are
employed by a company as a sales person, and you eventually become the sales manager of a…
Accounting Principles: Managerial Accounting
Process: Cost systems
Learning objectives
After studying this chapter, you should be able to:
• Describe the types of operations that require a process cost system.
• Distinguish between process and job costing systems.
• Discuss the concept…
Learning objectives
After studying this chapter, you should be able to:
• Describe the types of operations that require a process cost system.
• Distinguish between process and job costing systems.
• Discuss the concept…
Principles of Management
Principles of Management is adapted from a work produced by a publisher who has requested that they and the original author not receive attribution. This adapted edition is produced by the University of Minnesota Libraries Publishing through the…
Clinical Pharmacy
What is Clinical Pharmacy
Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/by-sa/3.0/ license.
Clinical pharmacy is the branch of pharmacy in which pharmacists provide patient care that optimizes the use of…
Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/by-sa/3.0/ license.
Clinical pharmacy is the branch of pharmacy in which pharmacists provide patient care that optimizes the use of…
Introduction to Human Osteology
Physical anthropologists study human biological variation in the past and present. They are not only interested in the physical aspect of the body but also how biology, culture and environment interact to produce variation. Part of this variation…
Introduction To Linear, Time-Invariant, Dynamic Systems For Students Of Engineering
Permission of the author is granted for reproduction in any form of this book or any part of this book, provided that there is appropriate attribution, for example, by a citation in the References section of a technical article, and provided that the…
Project Management For Instructional Designers
Project Management for Instructional Designers (PM4ID) is – as the name suggests – a book about project management tailored specifically for instructional designers. This book is a revise / remix of a pre-existing, openly licensed project management…
Non-Isothermal Kinetic Methods
In the modern world of ever-advancing technologies, actual tests of products and processes are more and more often preceded, if not replaced, by computer modeling. This saves the time and resources required for actual tests, and enables a better…
eGIRLS, eCITIZENS
eGirls, eCitizens is a landmark work that explores the many forces that shape girls’ and young women’s experiences of privacy, identity, and equality in our digitally networked society. Drawing on the multi-disciplinary expertise of a remarkable team…
A Guide to Veterinary Clinical Skills Laboratories
Clinical and practical skills are an essential part of the competences required of veterinary graduates (European Association of Establishments for Veterinary
Education (EAEVE) 2014, Royal College of Veterinary Surgeons (RCVS) 2014 American…
Education (EAEVE) 2014, Royal College of Veterinary Surgeons (RCVS) 2014 American…
Advances in Biotechnology Volume 1
The results of our investigation on the microbial community of the high-temperature Dagang oilfield (P.R. China) are summarized. Detailed experimental data are provided on syntrophic acetate degradation by thermophilic associations, on the isolation…
Agile Processes in Software Engineering and Extreme Programming
A retrospective is a standard agile meeting practice designed for agile software teams to reflect and tune their process. Despite its integral importance, we know little about what aspects are focused upon during retrospectives and how reflection…
What Works in Conservation
This book has been created to help you make decisions about practical conservation management by providing an assessment, from the available scientific evidence, of what works and what does not work in conservation.
It also tells you if no evidence…
It also tells you if no evidence…
The Busy Coder's Guide to Android Development
Thanks for your interest in developing applications for Android! Increasingly, people will access Internet-based services using so-called "non-traditional" means, such as mobile devices. The more we do in that space now, the more that…
The Economics of Food and Agricultural Markets
The Economics of agriculture is important and interesting! Food and agricultural markets are in the news and on social media every day. Numerous fascinating and
complex issues are the subject of this course: food prices, food safety, diet and…
complex issues are the subject of this course: food prices, food safety, diet and…
The Art of Insight in Science and Engineering
Science and engineering, our modern ways of understanding and altering the world, are said to be about accuracy and precision. Yet we best master the complexity of our world by cultivating insight rather than precision.
We need insight because our…
We need insight because our…
Sustainable Food Systems
This book places itself within the traditions and the ongoing activity of UCL’s Bartlett Development Planning Unit, and within its research cluster, Environmental
Justice, Urbanisation & Resilience. It draws heavily upon my teaching for the…
Justice, Urbanisation & Resilience. It draws heavily upon my teaching for the…
Socioeconomics of Agriculture
Socioeconomics may be under greater pressure to define itself than the “classical” sciences. The latter have largely been defined by the conceptualization of real-world
phenomena: biology, for example, arose because of the willingness to better…
phenomena: biology, for example, arose because of the willingness to better…
Small-signal stability, control and dynamic performance of
power systems
The main purpose of this book is to introduce the graduate engineer to the concepts and applications of small-signal analysis and controller design for the enhancement of the dynamic performance of multi-machine power systems.
To this end, the…
To this end, the…
Agricultural Implications of the Fukushima Nuclear Accident
This book reports the results from on-site research into radioactive cesium contamination in various agricultural systems affected by the Fukushima Daiichi Nuclear Power Plant accident that occurred in March 2011. This is the second volume from the…
Agricultural Input Subsidies
Up to date review of theory and experience of agricultural input subsidies in low income countries, with new theoretical and empirical insights
Detailed and comprehensive analysis of the Malawi Agricultural Input Subsidy Programme
Strong emphasis…
Detailed and comprehensive analysis of the Malawi Agricultural Input Subsidy Programme
Strong emphasis…
Animal (De)liberation: Should the Consumption of Animal Products Be Banned?
In this book, Jan Deckers addresses the most crucial question that people must deliberate in relation to how we should treat other animals: whether we should eat animal products. Many people object to the consumption of animal products from the…
Animal Metropolis
Animal Metropolis brings a Canadian perspective to the growing field of animal history, ranging across species and cities, from the beavers who engineered Stanley Park to the carthorses who shaped the city of Montreal. Some essays consider animals as…
Aquaculture Perspective of Multi-Use Sites in the Open Ocean: The Untapped Potential for Marine Resources in the Anthropocene
The first-of-its-kind compilation that comprehensively explores the scientific, engineering, economic and policy aspects of marine aquaculture multi-use of offshore platforms
A timely analysis of the rapid development of offshore energy production…
A timely analysis of the rapid development of offshore energy production…
Care in Healthcare: Reflections on Theory and Practice
This book examines the concept of care and care practices in healthcare from the interdisciplinary perspectives of continental philosophy, care ethics, the social sciences, and anthropology. Areas addressed include dementia care, midwifery, diabetes…
Climate Smart Agriculture: Building Resilience to Climate Change
The book uses an economic lens to identify the main features of climate-smart agriculture (CSA), its likely impact, and the challenges associated with its implementation. Drawing upon theory and concepts from agricultural development, institutional,…
Diseases of Children in the Subtropics and Tropics
Paediatrics is often thought of as following two main routes. One is that of ultra-technology and ever-narrower specialization. The other is recognition of child health in a community context, related to family circumstances (especially the health…
Electromagnetic Fields and Energy
Published in 1989 by Prentice-Hall, this book is a useful resource for educators and self-learners alike. The text is aimed at those who have seen Maxwell's equations in integral and differential form and who have been exposed to some integral…
Electromagnetics Volume I
Published in 1989 by Prentice-Hall, this book is a useful resource for educators and self-learners alike. The text is aimed at those who have seen Maxwell's equations in integral and differential form and who have been exposed to some integral…
Electromechanical Dynamics
First published in 1968 by John Wiley and Sons, Inc., Electromechanical Dynamics discusses the interaction of electromagnetic fields with media in motion. The subject combines classical mechanics and electromagnetic theory and provides opportunities…
Elements of Robotics
This book bridges the gap between playing with robots in school and studying robotics at the upper undergraduate and graduate levels to prepare for careers in industry and research. Robotic algorithms are presented formally, but using only…
Energy Poverty
This book is the direct result of nearly five years of work on the Energy Vulnerability and Urban Transitions in Europe project (www.urbanenergy.org), generously
supported by a Starting Grant from the European Research Council—under the European…
supported by a Starting Grant from the European Research Council—under the European…
Ethics and Civil Drones
This open access book disseminates some of the results of the European H2020 AiRT Project (Technology transfer of RPAs for the creative industry). In particular, it presents findings related to mitigating safety and security concerns when civil…
Field Trials of Health Interventions: A Toolbox
Abstract
Before new interventions are released into disease control programmes, it is essential that they are carefully evaluated in `field trials'. These may be complex and expensive undertakings, requiring the follow-up of hundreds, or…
Before new interventions are released into disease control programmes, it is essential that they are carefully evaluated in `field trials'. These may be complex and expensive undertakings, requiring the follow-up of hundreds, or…
Forest Measurements: an Applied Approach
This is a forest measurements textbook written for field technicians. Silvicultural applications and illustrations are provided to demonstrate the relevance of the measurements. Special “technique tips” for each skill are intended to help increase…
Fundamentals of Infrastructure Management
The authors believe this free of charge book, Fundamentals of Infrastructure Management, will expand the impact of the material and help improve the practice of infrastructure management. By ‘free of charge,’ we mean that the material can be freely…
Health Case Studies
Health Case Studies is composed of eight separate health case studies. Each case study includes the patient narrative or story that models the best practice (at the time of publishing) in healthcare settings. Associated with each case is a set of…
Interface Oral Health Science 2016: Innovative Research on Biosis–Abiosis Intelligent Interface
This volume broadens understanding of dentistry and promotes interdisciplinary research across a wide range of related fields, based on the symposium entitled "Innovative Research for Biosis–Abiosis Intelligent Interface 2016". It aims to create…
Leak Detection Technology and Implementation
Leak Detection: Technology and Implementation assists water utilities with the development and implementation of leak detection programs. Leak detection and repair is one of the components of controlling water loss. In addition, techniques are…
Math, Numerics, & Programming (for Mechanical Engineers)
All readings are from the textbook: Masayuki Yano, et al. Math, Numerics, and Programming (for Mechanical Engineers). V2.1, August 2013. Files for each available unit are provided in the following table, courtesy of the authors. The entire textbook…
Public Health Ethics: Cases Spanning the Globe
This Open Access book highlights the ethical issues and dilemmas that arise in the practice of public health. It is also a tool to support instruction, debate, and dialogue regarding public health ethics. Although the practice of public health has…
Sago Palm: Multiple Contributions to Food Security and Sustainable Livelihoods
This book addresses a wide variety of events and technologies concerning the sago palm, ranging from its botanical characteristics, culture and use to social conditions in the places where it is grown, in order to provide a record of research…
Animals and the Shaping of Modern Medicine:
One Health and its Histories
This book breaks new ground by situating animals and their diseases at the very heart of modern medicine. In demonstrating their historical significance as subjects and shapers of medicine, it offers important insights into past animal lives, and…
DC Circuits
This book covers Direct Current (DC) circuit theory and is broken up into three modules. Module 1 covers the basics for circuits that include DC sources (voltage or current) and resistors. Even though Module 1 is not very difficult, it forms the…
Information Technology and the Networked Economy
The beginning of the 21st century has seen a rapid change from the industrial economy to a networked economy built on computers, connectivity, and human
knowledge. The networked economy is characterized by rapidly changing market
conditions and…
knowledge. The networked economy is characterized by rapidly changing market
conditions and…
Malarial Subjects
Malaria was considered one of the most widespread disease-causing entities in the nineteenth century. It was associated with a variety of frailties far beyond fevers, ranging from idiocy to impotence. And yet, it was not a self-contained category.…
Nursing Care at the End of Life: What Every Clinician Should Know
Nursing Care at the End of Life: What Every Clinician Should Know should be an essential component of basic educational preparation for the professional registered nurse student. Recent studies show that only one in four nurses feel confident in…
Plants, Society, and the Environment
Affordable Learning Georgia Grants Collections are intended to provide faculty with the frameworks to quickly implement or revise the same materials as a Textbook Transformation Grants team, along with the aims and lessons learned from project teams…
UGA Anatomy and Physiology 1 Lab Manual
The manual contains the following labs:
Introduction
Tissues
Integument
Introduction to the Skeleton
Axial Skeleton: Skull
Axial Skeleton: Vertebral
Appendicular Skeleton: Introduction and Pectoral Girdle
…
Introduction
Tissues
Integument
Introduction to the Skeleton
Axial Skeleton: Skull
Axial Skeleton: Vertebral
Appendicular Skeleton: Introduction and Pectoral Girdle
…
UGA Anatomy and Physiology 2 Lab Manual
The manual contains the following labs:
Blood Composition
Blood Typing
Heart Anatomy
Cardiovascular Physiology
Systemic Blood Vessels
Anatomy of the Respiratory System
Physiology of the Respiratory System
…
Blood Composition
Blood Typing
Heart Anatomy
Cardiovascular Physiology
Systemic Blood Vessels
Anatomy of the Respiratory System
Physiology of the Respiratory System
…
Energy Poverty : (Dis)Assembling Europe’s Infrastructural Divide
EVALUATE is a multi-sited study, involving extensive research across a variety of cities and countries. Focusing primarily on four Central and Eastern European cities (Budapest, Gdańsk, Prague and Skopje) the project has undertaken a customized…
Meat Cutting and Processing for Food Service
This book is intended to give students a basic understanding of the various types of meat and poultry used in the food service industry, and how the terminology used by retail, wholesale, and food service customers varies. Meat cutting for…
Medical Virology
Medical virology is always an interest to all healthcare disciplines, undergraduate and
postgraduate students. These “Notes on Medical virology”, includes “what you really need to know”. The book comes in a new format, which places cases, keywords,…
postgraduate students. These “Notes on Medical virology”, includes “what you really need to know”. The book comes in a new format, which places cases, keywords,…
Digital Scholarly Editing : Theories and Practices
"This volume presents the state of the art in digital scholarly editing. Drawing together the work of established and emerging researchers, it gives pause at a crucial moment in the history of technology in order to offer a sustained reflection on…
Beyond Lean: Simulation in Practice, Second Edition
Lean thinking, as well as associated processes and tools, have involved into a ubiquitous perspective for improving systems particularly in the manufacturing arena. With application experience has come an understanding of the boundaries of lean…
Emerging Technologies
Despite all advances in computing technologies, the human-computer interface and the interactions that it provides are the most fundamental. Some of the most anticipated advancements in computer technology lie in the area of interfaces – not least…
Manufacturing and Inspection Technologies
In this module, we will look at how manufacturing systems have developed over the years, comparing and contrasting the various systems that have sprung up in different countries. We will then move into the present as we study four modern…
Respiratory System
The job of the respiratory system is to take oxygen from the air we breathe and get it to different parts of the body. Our bodies and the cells in them need oxygen (written with the chemical symbol O2) to live. Our cells give off carbon dioxide…
Circulatory System
The circulatory system includes the heart, blood, and a huge network of blood vessels that carry blood all over the body. The job of the circulatory system is to deliver oxygen to cells all over the body and then to carry out waste product like…
Digestive System
Our bodies need food to live and grow. The digestive system takes food and carries it to all the parts of the body.
The beginning of the digestive system is the mouth and teeth. Food that we eat has to be broken down into nutrients that cells in…
The beginning of the digestive system is the mouth and teeth. Food that we eat has to be broken down into nutrients that cells in…
Excretory System
After food goes through the digestive system, the parts that are not digested need to be gotten rid of. That is the job of the excretory system.
Unabsorbed food goes to the large intestine. The liver also filters out solid particles of waste from…
Unabsorbed food goes to the large intestine. The liver also filters out solid particles of waste from…
The Human Skeleton
The human skeleton provides shape and form to the human body
Our vital organs in our body are protected by our skeleton. More specifically our brain which is protected by what is called the skull and our heart and lungs are protected by our rib…
Our vital organs in our body are protected by our skeleton. More specifically our brain which is protected by what is called the skull and our heart and lungs are protected by our rib…
Cardio
Cardio Exercises Below
1) Jog. You can do this outside on a treadmill or however you like.
2) Jump Rope routine 1
3) 10 Minute Jump Rope routine
4) Exercise Bikes
5) Sports Playing
1) Jog. You can do this outside on a treadmill or however you like.
2) Jump Rope routine 1
3) 10 Minute Jump Rope routine
4) Exercise Bikes
5) Sports Playing
Chambers and Circulation through the Heart
Dual System of the Human Blood Circulation. Blood flows from the right atrium to the right ventricle, where it is pumped into the pulmonary circuit. The blood in the pulmonary artery branches is low in oxygen but relatively high in carbon dioxide.…
Shoulder Joint
The shoulder joint is called the glenohumeral joint. This is a ball-and-socket joint formed by the articulation between the head of the humerus and the glenoid cavity of the scapula ([link]). This joint has the largest range of motion of any joint in…
Levels of Structural Organization of the Human Body
Before you begin to study the different structures and functions of the human body, it is helpful to consider its basic architecture; that is, how its smallest parts are assembled into larger structures. It is convenient to consider the structures of…
Positive Feedback Loop
Normal childbirth is driven by a positive feedback loop. A positive feedback loop results in a change in the body’s status, rather than a return to homeostasis.
Dorsal and Ventral Body Cavities
The posterior (dorsal) and anterior (ventral) cavities are each subdivided into smaller cavities. In the posterior (dorsal) cavity, the cranial cavity houses the brain, and the spinal cavity (or vertebral cavity) encloses the spinal cord. Just as the…
Regions and Quadrants of the Peritoneal Cavity
The more detailed regional approach subdivides the cavity with one horizontal line immediately inferior to the ribs and one immediately superior to the pelvis, and two vertical lines drawn as if dropped from the midpoint of each clavicle…
Serous Membrane
A serous membrane (also referred to a serosa) is one of the thin membranes that cover the walls and organs in the thoracic and abdominopelvic cavities. The parietal layers of the membranes line the walls of the body cavity (pariet- refers to a cavity…
Animals & Ethics 101: Thinking Critically About Animal Rights
This book provides an overview of the current debates about the nature and extent of our moral obligations to animals. Which, if any, uses of animals are morally wrong, which are morally permissible (i.e., not wrong) and why? What, if any, moral…
Creative Clinical Teaching In The Health Professions
This peer reviewed e-book is a must-read for nurses and other health professionals who strive to teach with creativity and excellence in clinical settings. Each chapter presents current evidence informed educational practice knowledge. Each topic is…
Health and Safety in Canadian Workplaces
Workplace injuries happen every day and can profoundly affect workers, their families, and the communities they live in. This textbook provides workers with an introduction to effective injury prevention. The book pays particular attention to how…
Human Anatomy and Physiology Preparatory Course
The overall purpose of this preparatory course textbook is to help students familiarize with some terms and some basic concepts they will find later in the Human Anatomy and Physiology I course. The organization and functioning of the human organism…
Literature Reviews for Education and Nursing Graduate Students
Literature Reviews for Education and Nursing Graduate Students is an open textbook designed for students in graduate-level nursing and education programs. Its intent is to recognize the significant role the literature review plays in the research…
X-Ray of a Hand
High energy electromagnetic radiation allows the internal structures of the body, such as bones, to be seen in X-rays like these
Medical Imaging Techniques
(a) The results of a CT scan of the head are shown as successive transverse sections. (b) An MRI machine generates a magnetic field around a patient. (c) PET scans use radiopharmaceuticals to create images of active blood flow and physiologic…
Elements of the Human Body
The main elements that compose the human body are shown from most abundant to least abundant.
Adenosine Triphosphate
The nucleotide adenosine triphosphate (ATP), is composed of a ribose sugar, an adenine base, and three phosphate groups ([link]). ATP is classified as a high energy compound because the two covalent bonds linking its three phosphates store a…
Fluorescence-stained Cell Undergoing Mitosis
A lung cell from a newt, commonly studied for its similarity to human lung cells, is stained with fluorescent dyes. The green stain reveals mitotic spindles, red is the cell membrane and part of the cytoplasm, and the structures that appear light…
Cell Membrane
The cell membrane of the cell is a phospholipid bilayer containing many different molecular components, including proteins and cholesterol, some with carbohydrate groups attached.
Simple Diffusion across the Cell (Plasma) Membrane
The structure of the lipid bilayer allows small, uncharged substances such as oxygen and carbon dioxide, and hydrophobic molecules such as lipids, to pass through the cell membrane, down their concentration gradient, by simple diffusion.
Facilitated Diffusion
(a) Facilitated diffusion of substances crossing the cell (plasma) membrane takes place with the help of proteins such as channel proteins and carrier proteins. Channel proteins are less selective than carrier proteins, and usually mildly…
Sodium-Potassium Pump
The sodium-potassium pump is found in many cell (plasma) membranes. Powered by ATP, the pump moves sodium and potassium ions in opposite directions, each against its concentration gradient. In a single cycle of the pump, three sodium ions are…
Three Forms of Endocytosis
Endocytosis is a form of active transport in which a cell envelopes extracellular materials using its cell membrane. (a) In phagocytosis, which is relatively nonselective, the cell takes in a large particle. (b) In pinocytosis, the cell takes in…
Exocytosis
Exocytosis is much like endocytosis in reverse. Material destined for export is packaged into a vesicle inside the cell. The membrane of the vesicle fuses with the cell membrane, and the contents are released into the extracellular space.
Fatty Acid Shapes
The level of saturation of a fatty acid affects its shape. (a) Saturated fatty acid chains are straight. (b) Unsaturated fatty acid chains are kinked.
Prototypical Human Cell
While this image is not indicative of any one particular human cell, it is a prototypical example of a cell containing the primary organelles and internal structures.
Endoplasmic Reticulum (ER)
(a) The ER is a winding network of thin membranous sacs found in close association with the cell nucleus. The smooth and rough endoplasmic reticula are very different in appearance and function (source: mouse tissue). (b) Rough ER is studded with…
Golgi Apparatus
(a) The Golgi apparatus manipulates products from the rough ER, and also produces new organelles called lysosomes. Proteins and other products of the ER are sent to the Golgi apparatus, which organizes, modifies, packages, and tags them. Some of…
Mitochondrion
The mitochondria are the energy-conversion factories of the cell. (a) A mitochondrion is composed of two separate lipid bilayer membranes. Along the inner membrane are various molecules that work together to produce ATP, the cell’s major energy…
The Three Components of the Cytoskeleton
The cytoskeleton consists of (a) microtubules, (b) microfilaments, and (c) intermediate filaments. The cytoskeleton plays an important role in maintaining cell shape and structure, promoting cellular movement, and aiding cell division.
The Nucleus
The nucleus is the control center of the cell. The nucleus of living cells contains the genetic material that determines the entire structure and function of that cell.
Multinucleate Muscle Cell
Unlike cardiac muscle cells and smooth muscle cells, which have a single nucleus, a skeletal muscle cell contains many nuclei, and is referred to as “multinucleated.” These muscle cells are long and fibrous (often referred to as muscle fibers).…
DNA Macrostructure
Strands of DNA are wrapped around supporting histones. These proteins are increasingly bundled and condensed into chromatin, which is packed tightly into chromosomes when the cell is ready to divide.
Molecular Structure of DNA
The DNA double helix is composed of two complementary strands. The strands are bonded together via their nitrogenous base pairs using hydrogen bonds.
DNA Replication
DNA replication faithfully duplicates the entire genome of the cell. During DNA replication, a number of different enzymes work together to pull apart the two strands so each strand can be used as a template to synthesize new complementary strands.…
The Genetic Code
DNA holds all of the genetic information necessary to build a cell’s proteins. The nucleotide sequence of a gene is ultimately translated into an amino acid sequence of the gene’s corresponding protein.
Transcription: from DNA to mRNA
In the first of the two stages of making protein from DNA, a gene on the DNA molecule is transcribed into a complementary mRNA molecule.
Splicing DNA
In the nucleus, a structure called a spliceosome cuts out introns (noncoding regions) within a pre-mRNA transcript and reconnects the exons.
Translation from RNA to Protein
During translation, the mRNA transcript is “read” by a functional complex consisting of the ribosome and tRNA molecules. tRNAs bring the appropriate amino acids in sequence to the growing polypeptide chain by matching their anti-codons with codons on…
From DNA to Protein: Transcription through Translation
Transcription within the cell nucleus produces an mRNA molecule, which is modified and then sent into the cytoplasm for translation. The transcript is decoded into a protein with the help of a ribosome and tRNA molecules.
A Homologous Pair of Chromosomes with their Attached Sister Chromatids
The red and blue colors correspond to a homologous pair of chromosomes. Each member of the pair was separately inherited from one parent. Each chromosome in the homologous pair is also bound to an identical sister chromatid, which is produced by DNA…
Cell Division: Mitosis
The stages of cell division oversee the separation of identical genetic material into two new nuclei, followed by the division of the cytoplasm.
Hematopoiesis
The process of hematopoiesis involves the differentiation of multipotent cells into blood and immune cells. The multipotent hematopoietic stem cells give rise to many different cell types, including the cells of the immune system and red blood cells.
Stem Cells
The capacity of stem cells to differentiate into specialized cells make them potentially valuable in therapeutic applications designed to replace damaged cells of different body tissues.
Micrograph of Cervical Tissue
This figure is a view of the regular architecture of normal tissue contrasted with the irregular arrangement of cancerous cells.
Four Types of Tissue: Body
The four types of tissues are exemplified in nervous tissue, stratified squamous epithelial tissue, cardiac muscle tissue, and connective tissue in small intestine. Clockwise from nervous tissue
Embryonic Origin of Tissues
The zygote, or fertilized egg, is a single cell formed by the fusion of an egg and sperm. After fertilization the zygote gives rise to rapid mitotic cycles, generating many cells to form the embryo. The first embryonic cells generated have the…
Tissue Membranes
The two broad categories of tissue membranes in the body are (1) connective tissue membranes, which include synovial membranes, and (2) epithelial membranes, which include mucous membranes, serous membranes, and the cutaneous membrane, in other…
Types of Cell Junctions
The three basic types of cell-to-cell junctions are tight junctions, gap junctions, and anchoring junctions.
Cells of Epithelial Tissue
Simple epithelial tissue is organized as a single layer of cells and stratified epithelial tissue is formed by several layers of cells.
Goblet Cell
(a) In the lining of the small intestine, columnar epithelium cells are interspersed with goblet cells. (b) The arrows in this micrograph point to the mucous-secreting goblet cells.
Summary of Epithelial Tissue Cells
A stratified epithelium consists of several stacked layers of cells. This epithelium protects against physical and chemical wear and tear. The stratified epithelium is named by the shape of the most apical layer of cells, closest to the free space.…
Types of Exocrine Glands
Exocrine glands are classified by their structure.
Modes of Glandular Secretion
(a) In merocrine secretion, the cell remains intact. (b) In apocrine secretion, the apical portion of the cell is released, as well. (c) In holocrine secretion, the cell is destroyed as it releases its product and the cell itself becomes part of the…
Sebaceous Glands
These glands secrete oils that lubricate and protect the skin. They are holocrine glands and they are destroyed after releasing their contents. New glandular cells form to replace the cells that are lost
Connective Tissue Proper
Fibroblasts produce this fibrous tissue. Connective tissue proper includes the fixed cells fibrocytes, adipocytes, and mesenchymal cells.
Adipose Tissue
This is a loose connective tissue that consists of fat cells with little extracellular matrix. It stores fat for energy and provides insulation.
Reticular Tissue
This is a loose connective tissue made up of a network of reticular fibers that provides a supportive framework for soft organs.
Dense Connective Tissue
(a) Dense regular connective tissue consists of collagenous fibers packed into parallel bundles. (b) Dense irregular connective tissue consists of collagenous fibers interwoven into a mesh-like network. From top,
Types of Cartilage
Cartilage is a connective tissue consisting of collagenous fibers embedded in a firm matrix of chondroitin sulfates. (a) Hyaline cartilage provides support with some flexibility. The example is from dog tissue. (b) Fibrocartilage provides some…
The Neuron
The cell body of a neuron, also called the soma, contains the nucleus and mitochondria. The dendrites transfer the nerve impulse to the soma. The axon carries the action potential away to another excitable cell.
Nervous Tissue
Nervous tissue is made up of neurons and neuroglia. The cells of nervous tissue are specialized to transmit and receive impulses
Layers of Skin
The skin is composed of two main layers: the epidermis, made of closely packed epithelial cells, and the dermis, made of dense, irregular connective tissue that houses blood vessels, hair follicles, sweat glands, and other structures. Beneath the…
Layers of the Epidermis
The epidermis of thick skin has five layers: stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
Cells of the Epidermis
The cells in the different layers of the epidermis originate from basal cells located in the stratum basale, yet the cells of each layer are distinctively different.
Layers of the Dermis
This stained slide shows the two components of the dermis—the papillary layer and the reticular layer. Both are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct.…
Skin Pigmentation
The relative coloration of the skin depends of the amount of melanin produced by melanocytes in the stratum basale and taken up by keratinocytes.
Moles
Moles range from benign accumulations of melanocytes to melanomas. These structures populate the landscape of our skin.
Vitiligo
Individuals with vitiligo experience depigmentation that results in lighter colored patches of skin. The condition is especially noticeable on darker skin.
Hair
Hair follicles originate in the epidermis and have many different parts.
Nails
The nail is an accessory structure of the integumentary system.
Eccrine Gland
Eccrine glands are coiled glands in the dermis that release sweat that is mostly water.
Thermoregulation
During strenuous physical activities, such as skiing (a) or running (c), the dermal blood vessels dilate and sweat secretion increases (b). These mechanisms prevent the body from overheating. In contrast, the dermal blood vessels constrict to…
Acne
Acne is a result of over-productive sebaceous glands, which leads to formation of blackheads and inflammation of the skin.
Bones Protect Brain
The cranium completely surrounds and protects the brain from non-traumatic injury.
Classifications of Bones
Bones are classified according to their shape.
Anatomy of a Long Bone
A typical long bone shows the gross anatomical characteristics of bone.
Periosteum and Endosteum
The periosteum forms the outer surface of bone, and the endosteum lines the medullary cavity.
Anatomy of a Flat Bone
This cross-section of a flat bone shows the spongy bone (diploë) lined on either side by a layer of compact bone.
Bone Features
The surface features of bones depend on their function, location, attachment of ligaments and tendons, or the penetration of blood vessels and nerves.
Bone Cells
Four types of cells are found within bone tissue. Osteogenic cells are undifferentiated and develop into osteoblasts. When osteoblasts get trapped within the calcified matrix, their structure and function changes, and they become osteocytes.…
Diagram of Compact Bone
(a) This cross-sectional view of compact bone shows the basic structural unit, the osteon. (b) In this micrograph of the osteon, you can clearly see the concentric lamellae and central canals.
Diagram of Spongy Bone
Spongy bone is composed of trabeculae that contain the osteocytes. Red marrow fills the spaces in some bones.
Paget's Disease
Normal leg bones are relatively straight, but those affected by Paget’s disease are porous and curved.
Diagram of Blood and Nerve Supply to Bone
Blood vessels and nerves enter the bone through the nutrient foramen.
Intramembranous Ossification
Intramembranous ossification follows four steps. (a) Mesenchymal cells group into clusters, and ossification centers form. (b) Secreted osteoid traps osteoblasts, which then become osteocytes. (c) Trabecular matrix and periosteum form. (d) Compact…
Endochondral Ossification
Endochondral ossification follows five steps. (a) Mesenchymal cells differentiate into chondrocytes. (b) The cartilage model of the future bony skeleton and the perichondrium form. (c) Capillaries penetrate cartilage. Perichondrium transforms into…
Longitudinal Bone Growth
The epiphyseal plate is responsible for longitudinal bone growth.
Progression from Epiphyseal Plate to Epiphyseal Line
As a bone matures, the epiphyseal plate progresses to an epiphyseal line. (a) Epiphyseal plates are visible in a growing bone. (b) Epiphyseal lines are the remnants of epiphyseal plates in a mature bone.
Types of Fractures
Compare healthy bone with different types of fractures: (a) closed fracture, (b) open fracture, (c) transverse fracture, (d) spiral fracture, (e) comminuted fracture, (f) impacted fracture, (g) greenstick fracture, and (h) oblique fracture.
Stages in Fracture Repair
The healing of a bone fracture follows a series of progressive steps: (a) A fracture hematoma forms. (b) Internal and external calli form. (c) Cartilage of the calli is replaced by trabecular bone. (d) Remodeling occurs.
Synthesis of Vitamin D
Sunlight is one source of vitamin D.
Graph Showing Relationship Between Age and Bone Mass
Bone density peaks at about 30 years of age. Women lose bone mass more rapidly than men.
Pathways in Calcium Homeostasis
The body regulates calcium homeostasis with two pathways; one is signaled to turn on when blood calcium levels drop below normal and one is the pathway that is signaled to turn on when blood calcium levels are elevated.
Axial and Appendicular Skeleton
The axial skeleton supports the head, neck, back, and chest and thus forms the vertical axis of the body. It consists of the skull, vertebral column (including the sacrum and coccyx), and the thoracic cage, formed by the ribs and sternum. The…
Parts of the Skull
The skull consists of the rounded brain case that houses the brain and the facial bones that form the upper and lower jaws, nose, orbits, and other facial structures.
Anterior View of Skull
An anterior view of the skull shows the bones that form the forehead, orbits (eye sockets), nasal cavity, nasal septum, and upper and lower jaws.
Lateral View of Skull
The lateral skull shows the large rounded brain case, zygomatic arch, and the upper and lower jaws. The zygomatic arch is formed jointly by the zygomatic process of the temporal bone and the temporal process of the zygomatic bone. The shallow space…
Cranial Fossae
The bones of the brain case surround and protect the brain, which occupies the cranial cavity. The base of the brain case, which forms the floor of cranial cavity, is subdivided into the shallow anterior cranial fossa, the middle cranial fossa, and…
Temporal Bone
A lateral view of the isolated temporal bone shows the squamous, mastoid, and zygomatic portions of the temporal bone.
External and Internal Views of Base of Skull
(a) The hard palate is formed anteriorly by the palatine processes of the maxilla bones and posteriorly by the horizontal plate of the palatine bones. (b) The complex floor of the cranial cavity is formed by the frontal, ethmoid, sphenoid, temporal,…
Posterior View of Skull
This view of the posterior skull shows attachment sites for muscles and joints that support the skull.
Sphenoid Bone
Shown in isolation in (a) superior and (b) posterior views, the sphenoid bone is a single midline bone that forms the anterior walls and floor of the middle cranial fossa. It has a pair of lesser wings and a pair of greater wings. The sella turcica…
Sagittal Section of Skull
This midline view of the sagittally sectioned skull shows the nasal septum.
Ethmoid Bone
The unpaired ethmoid bone is located at the midline within the central skull. It has an upward projection, the crista galli, and a downward projection, the perpendicular plate, which forms the upper nasal septum. The cribriform plates form both the…
Lateral Wall of Nasal Cavity
The three nasal conchae are curved bones that project from the lateral walls of the nasal cavity. The superior nasal concha and middle nasal concha are parts of the ethmoid bone. The inferior nasal concha is an independent bone of the sku
Maxillary Bone
The maxillary bone forms the upper jaw and supports the upper teeth. Each maxilla also forms the lateral floor of each orbit and the majority of the hard palate.
Isolated Mandible
The mandible is the only moveable bone of the skull.
Bones of the Orbit
Seven skull bones contribute to the walls of the orbit. Opening into the posterior orbit from the cranial cavity are the optic canal and superior orbital fissure.
Nasal Septum
The nasal septum is formed by the perpendicular plate of the ethmoid bone and the vomer bone. The septal cartilage fills the gap between these bones and extends into the nose.
Paranasal Sinuses
The paranasal sinuses are hollow, air-filled spaces named for the skull bone that each occupies. The most anterior is the frontal sinus, located in the frontal bone above the eyebrows. The largest are the maxillary sinuses, located in the right and…
Hyoid Bone
The hyoid bone is located in the upper neck and does not join with any other bone. It provides attachments for muscles that act on the tongue, larynx, and pharynx.
Vertebral Column
The adult vertebral column consists of 24 vertebrae, plus the sacrum and coccyx. The vertebrae are divided into three regions: cervical C1–C7 vertebrae, thoracic T1–T12 vertebrae, and lumbar L1–L5 vertebrae. The vertebral column is curved, with two…
Abnormal Curvatures of the Vertebral Column
(a) Scoliosis is an abnormal lateral bending of the vertebral column. (b) An excessive curvature of the upper thoracic vertebral column is called kyphosis. (c) Lordosis is an excessive curvature in the lumbar region of the vertebral column.
Osteoporosis
Osteoporosis is an age-related disorder that causes the gradual loss of bone density and strength. When the thoracic vertebrae are affected, there can be a gradual collapse of the vertebrae. This results in kyphosis, an excessive curvature of the…
Parts of a Typical Vertebra
A typical vertebra consists of a body and a vertebral arch. The arch is formed by the paired pedicles and paired laminae. Arising from the vertebral arch are the transverse, spinous, superior articular, and inferior articular processes. The vertebral…
Intervertebral Disc
The bodies of adjacent vertebrae are separated and united by an intervertebral disc, which provides padding and allows for movements between adjacent vertebrae. The disc consists of a fibrous outer layer called the anulus fibrosus and a gel-like…
Cervical Vertebrae
A typical cervical vertebra has a small body, a bifid spinous process, transverse processes that have a transverse foramen and are curved for spinal nerve passage. The atlas (C1 vertebra) does not have a body or spinous process. It consists of an…
Thoracic Vertebrae
A typical thoracic vertebra is distinguished by the spinous process, which is long and projects downward to overlap the next inferior vertebra. It also has articulation sites (facets) on the vertebral body and a transverse process for rib attachment.
Lumbar Vertebrae
Lumbar vertebrae are characterized by having a large, thick body and a short, rounded spinous process.
Sacrum and Coccyx
The sacrum is formed from the fusion of five sacral vertebrae, whose lines of fusion are indicated by the transverse ridges. The fused spinous processes form the median sacral crest, while the lateral sacral crest arises from the fused transverse…
Herniated Intervertebral Disc
Weakening of the anulus fibrosus can result in herniation (protrusion) of the nucleus pulposus and compression of a spinal nerve, resulting in pain and/or muscle weakness in the body regions supplied by that nerve.
Ligaments of Vertebral Column
The anterior longitudinal ligament runs the length of the vertebral column, uniting the anterior sides of the vertebral bodies. The supraspinous ligament connects the spinous processes of the thoracic and lumbar vertebrae. In the posterior neck, the…
Rib Articulation in Thoracic Vertebrae
Thoracic vertebrae have superior and inferior articular facets on the vertebral body for articulation with the head of a rib, and a transverse process facet for articulation with the rib tubercle.
Thoracic Cage
The thoracic cage is formed by the (a) sternum and (b) 12 pairs of ribs with their costal cartilages. The ribs are anchored posteriorly to the 12 thoracic vertebrae. The sternum consists of the manubrium, body, and xiphoid process. The ribs are…
Newborn Skull
The bones of the newborn skull are not fully ossified and are separated by large areas called fontanelles, which are filled with fibrous connective tissue. The fontanelles allow for continued growth of the skull after birth. At the time of birth, the…
Pectoral Girdle
The pectoral girdle consists of the clavicle and the scapula, which serve to attach the upper limb to the sternum of the axial skeleton.
Scapula
The isolated scapula is shown here from its anterior (deep) side and its posterior (superficial) side.
Humerus and Elbow Joint
The humerus is the single bone of the upper arm region. It articulates with the radius and ulna bones of the forearm to form the elbow joint.
Ulna and Radius
The ulna is located on the medial side of the forearm, and the radius is on the lateral side. These bones are attached to each other by an interosseous membrane.
Bones of the Wrist and Hand
The eight carpal bones form the base of the hand. These are arranged into proximal and distal rows of four bones each. The metacarpal bones form the palm of the hand. The thumb and fingers consist of the phalanx bones.
Bones of the Hand
This radiograph shows the position of the bones within the hand. Note the carpal bones that form the base of the hand
Carpal Tunnel
The carpal tunnel is the passageway by which nine muscle tendons and a major nerve enter the hand from the anterior forearm. The walls and floor of the carpal tunnel are formed by the U-shaped grouping of the carpal bones, and the roof is formed by…
Hand During Gripping
During tight gripping—compare (b) to (a)—the fourth and, particularly, the fifth metatarsal bones are pulled anteriorly. This increases the contact between the object and the medial side of the hand, thus improving the firmness of the grip.
Fractures of the Humerus and Radius
Falls or direct blows can result in fractures of the surgical neck or shaft of the humerus. Falls onto the elbow can fracture the distal humerus. A Colles fracture of the distal radius is the most common forearm fracture.
Pelvis
The pelvic girdle is formed by a single hip bone. The hip bone attaches the lower limb to the axial skeleton through its articulation with the sacrum. The right and left hip bones, plus the sacrum and the coccyx, together form the pelvis.
The Hip Bone
The adult hip bone consists of three regions. The ilium forms the large, fan-shaped superior portion, the ischium forms the posteroinferior portion, and the pubis forms the anteromedial portion.
Ligaments of the Pelvis
The posterior sacroiliac ligament supports the sacroiliac joint. The sacrospinous ligament spans the sacrum to the ischial spine, and the sacrotuberous ligament spans the sacrum to the ischial tuberosity. The sacrospinous and sacrotuberous ligaments…
Male and Female Pelvis
The female pelvis is adapted for childbirth and is broader, with a larger subpubic angle, a rounder pelvic brim, and a wider and more shallow lesser pelvic cavity than the male pelvis.
Femur and Patella
The femur is the single bone of the thigh region. It articulates superiorly with the hip bone at the hip joint, and inferiorly with the tibia at the knee joint. The patella only articulates with the distal end of the femur.
The Q-Angle
The Q-angle is a measure of the amount of lateral deviation of the femur from the vertical line of the tibia. Adult females have a larger Q-angle due to their wider pelvis than adult males.
Tibia and Fibula
The tibia is the larger, weight-bearing bone located on the medial side of the leg. The fibula is the slender bone of the lateral side of the leg and does not bear weight.
Bones of the Foot
The bones of the foot are divided into three groups. The posterior foot is formed by the seven tarsal bones. The mid-foot has the five metatarsal bones. The toes contain the phalanges.
Embryo at Seven Weeks
Limb buds are visible in an embryo at the end of the seventh week of development (embryo derived from an ectopic pregnancy)
Clubfoot
Clubfoot
This photograph shows a baby with a clubfoot.Clubfoot is a common deformity of the ankle and foot that is present at birth. Most cases are corrected without surgery, and affected individuals will grow up to lead normal, active lives.…
This photograph shows a baby with a clubfoot.Clubfoot is a common deformity of the ankle and foot that is present at birth. Most cases are corrected without surgery, and affected individuals will grow up to lead normal, active lives.…
Suture Joints of Skull
The suture joints of the skull are an example of a synarthrosis, an immobile or essentially immobile joint.
Multiaxial Joint
A multiaxial joint, such as the hip joint, allows for three types of movement: anterior-posterior, medial-lateral, and rotational.
Fibrous Joints
Fibrous joints form strong connections between bones. (a) Sutures join most bones of the skull. (b) An interosseous membrane forms a syndesmosis between the radius and ulna bones of the forearm. (c) A gomphosis is a specialized fibrous joint that…
The Newborn Skull
The fontanelles of a newborn’s skull are broad areas of fibrous connective tissue that form fibrous joints between the bones of the skull.
Synovial Joints
Synovial joints allow for smooth movements between the adjacent bones. The joint is surrounded by an articular capsule that defines a joint cavity filled with synovial fluid. The articulating surfaces of the bones are covered by a thin layer of…
Bursae
Bursae are fluid-filled sacs that serve to prevent friction between skin, muscle, or tendon and an underlying bone. Three major bursae and a fat pad are part of the complex joint that unites the femur and tibia of the leg.
Types of Synovial Joints
The six types of synovial joints allow the body to move in a variety of ways. (a) Pivot joints allow for rotation around an axis, such as between the first and second cervical vertebrae, which allows for side-to-side rotation of the head. (b) The…
Osteoarthritis
Osteoarthritis of a synovial joint results from aging or prolonged joint wear and tear. These cause erosion and loss of the articular cartilage covering the surfaces of the bones, resulting in inflammation that causes joint stiffness and pain.
Movements of the Body, Part 1
Synovial joints give the body many ways in which to move. (a)–(b) Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist, metacarpophalangeal,…
Movements of the Body, Part 2
(g) Supination of the forearm turns the hand to the palm forward position in which the radius and ulna are parallel, while forearm pronation turns the hand to the palm backward position in which the radius crosses over the ulna to form an "X." (h)…
Atlantoaxial Joint
The atlantoaxial joint is a pivot type of joint between the dens portion of the axis (C2 vertebra) and the anterior arch of the atlas (C1 vertebra), with the dens held in place by a ligament.
Temporomandibular Joint
The temporomandibular joint is the articulation between the temporal bone of the skull and the condyle of the mandible, with an articular disc located between these bones. During depression of the mandible (opening of the mouth), the mandibular…
Glenohumeral Joint
The glenohumeral (shoulder) joint is a ball-and-socket joint that provides the widest range of motions. It has a loose articular capsule and is supported by ligaments and the rotator cuff muscles.
Elbow Joint
(a) The elbow is a hinge joint that allows only for flexion and extension of the forearm. (b) It is supported by the ulnar and radial collateral ligaments. (c) The annular ligament supports the head of the radius at the proximal radioulnar joint, the…
Hip Joint
(a) The ball-and-socket joint of the hip is a multiaxial joint that provides both stability and a wide range of motion. (b–c) When standing, the supporting ligaments are tight, pulling the head of the femur into the acetabulum.
Knee Joint
(a) The knee joint is the largest joint of the body. (b)–(c) It is supported by the tibial and fibular collateral ligaments located on the sides of the knee outside of the articular capsule, and the anterior and posterior cruciate ligaments found…
Knee Injury
A strong blow to the lateral side of the extended knee will cause three injuries, in sequence: tearing of the tibial collateral ligament, damage to the medial meniscus, and rupture of the anterior cruciate ligament.
Ankle Joint
The talocrural (ankle) joint is a uniaxial hinge joint that only allows for dorsiflexion or plantar flexion of the foot. Movements at the subtalar joint, between the talus and calcaneus bones, combined with motions at other intertarsal joints,…
The Three Types of Muscle Tissue
The body contains three types of muscle tissue: (a) skeletal muscle, (b) smooth muscle, and (c) cardiac muscle.
The Three Connective Tissue Layers
Bundles of muscle fibers, called fascicles, are covered by the perimysium. Muscle fibers are covered by the endomysium.
Muscle Fiber
A skeletal muscle fiber is surrounded by a plasma membrane called the sarcolemma, which contains sarcoplasm, the cytoplasm of muscle cells. A muscle fiber is composed of many fibrils, which give the cell its striated appearance.
The Sarcomere
The sarcomere, the region from one Z-line to the next Z-line, is the functional unit of a skeletal muscle fiber.
Motor End-Plate and Innervation
At the NMJ, the axon terminal releases ACh. The motor end-plate is the location of the ACh-receptors in the muscle fiber sarcolemma. When ACh molecules are released, they diffuse across a minute space called the synaptic cleft and bind to the…
The T-tubule
Narrow T-tubules permit the conduction of electrical impulses. The SR functions to regulate intracellular levels of calcium. Two terminal cisternae (where enlarged SR connects to the T-tubule) and one T-tubule comprise a triad—a “threesome” of…
Contraction of a Muscle Fiber
A cross-bridge forms between actin and the myosin heads triggering contraction. As long as Ca++ ions remain in the sarcoplasm to bind to troponin, and as long as ATP is available, the muscle fiber will continue to shorten.
Relaxation of a Muscle Fiber
Ca++ ions are pumped back into the SR, which causes the tropomyosin to reshield the binding sites on the actin strands. A muscle may also stop contracting when it runs out of ATP and becomes fatigued.
The Sliding Filament Model of Muscle Contraction
When a sarcomere contracts, the Z lines move closer together, and the I band becomes smaller. The A band stays the same width. At full contraction, the thin and thick filaments overlap completely.
Skeletal Muscle Contraction
(a) The active site on actin is exposed as calcium binds to troponin. (b) The myosin head is attracted to actin, and myosin binds actin at its actin-binding site, forming the cross-bridge. (c) During the power stroke, the phosphate generated in the…
Muscle Metabolism
(a) Some ATP is stored in a resting muscle. As contraction starts, it is used up in seconds. More ATP is generated from creatine phosphate for about 15 seconds. (b) Each glucose molecule produces two ATP and two molecules of pyruvic acid, which can…
Types of Muscle Contractions
During isotonic contractions, muscle length changes to move a load. During isometric contractions, muscle length does not change because the load exceeds the tension the muscle can generate.
Atrophy
Muscle mass is reduced as muscles atrophy with disuse.
Cardiac Muscle
Intercalated discs are part of the cardiac muscle sarcolemma and they contain gap junctions and desmosomes.
Smooth Muscle Tissue
Smooth muscle tissue is found around organs in the digestive, respiratory, reproductive tracts and the iris of the eye.
Muscle Contraction
The dense bodies and intermediate filaments are networked through the sarcoplasm, which cause the muscle fiber to contract.
Motor Units
A series of axon-like swelling, called varicosities or “boutons,” from autonomic neurons form motor units through the smooth muscle.
Prime Movers and Synergists
The biceps brachii flex the lower arm. The brachoradialis, in the forearm, and brachialis, located deep to the biceps in the upper arm, are both synergists that aid in this motion.
Muscle Shapes and Fiber Alignment
The skeletal muscles of the body typically come in seven different general shapes.
Overview of the Muscular System
On the anterior and posterior views of the muscular system above, superficial muscles (those at the surface) are shown on the right side of the body while deep muscles (those underneath the superficial muscles) are shown on the left half of the body.…
Muscles of Facial Expression
Many of the muscles of facial expression insert into the skin surrounding the eyelids, nose and mouth, producing facial expressions by moving the skin rather than bones.
Muscles of the Eyes
(a) The extrinsic eye muscles originate outside of the eye on the skull. (b) Each muscle inserts onto the eyeball.
Muscles That Move the Lower Jaw
The muscles that move the lower jaw are typically located within the cheek and originate from processes in the skull. This provides the jaw muscles with the large amount of leverage needed for chewing.
Muscles That Move the Tongue
Tongue muscles can be extrinsic or intrinsic. Extrinsic tongue muscles insert into the tongue from outside origins, and the intrinsic tongue muscles insert into the tongue from origins within it. The extrinsic muscles move the whole tongue in…
Muscles of the Anterior Neck
The anterior muscles of the neck facilitate swallowing and speech. The suprahyoid muscles originate from above the hyoid bone in the chin region. The infrahyoid muscles originate below the hyoid bone in the lower neck.
Posterior and Lateral Views of the Neck
The superficial and deep muscles of the neck are responsible for moving the head, cervical vertebrae, and scapulas.
Muscles of the Neck and Back
The large, complex muscles of the neck and back move the head, shoulders, and vertebral column.
Muscles of the Abdomen
(a) The anterior abdominal muscles include the medially located rectus abdominis, which is covered by a sheet of connective tissue called the rectus sheath. On the flanks of the body, medial to the rectus abdominis, the abdominal wall is composed of…
Muscles of the Diaphragm
The diaphragm separates the thoracic and abdominal cavities.
Intercostal Muscles
The external intercostals are located laterally on the sides of the body. The internal intercostals are located medially near the sternum. The innermost intercostals are located deep to both the internal and external intercostals.
Muscles of the Pelvic Floor
The pelvic floor muscles support the pelvic organs, resist intra-abdominal pressure, and work as sphincters for the urethra, rectum, and vagina.
Muscles That Position the Pectoral Girdle
The muscles that stabilize the pectoral girdle make it a steady base on which other muscles can move the arm. Note that the pectoralis major and deltoid, which move the humerus, are cut here to show the deeper positioning muscles.
Muscles That Move the Humerus
(a, c) The muscles that move the humerus anteriorly are generally located on the anterior side of the body and originate from the sternum (e.g., pectoralis major) or the anterior side of the scapula (e.g., subscapularis). (b) The muscles that move…
Muscles That Move the Forearm
The muscles originating in the upper arm flex, extend, pronate, and supinate the forearm. The muscles originating in the forearm move the wrists, hands, and fingers.
Intrinsic Muscles of the Hand
The intrinsic muscles of the hand both originate and insert within the hand. These muscles provide the fine motor control of the fingers by flexing, extending, abducting, and adducting the more distal finger and thumb segments.
Hip and Thigh Muscles
The large and powerful muscles of the hip that move the femur generally originate on the pelvic girdle and insert into the femur. The muscles that move the lower leg typically originate on the femur and insert into the bones of the knee joint. The…
Intrinsic Muscles of the Foot
The muscles along the dorsal side of the foot (a) generally extend the toes while the muscles of the plantar side of the foot (b, c, d) generally flex the toes. The plantar muscles exist in three layers, providing the foot the strength to…
Muscles of the Lower Leg
The muscles of the anterior compartment of the lower leg are generally responsible for dorsiflexion, and the muscles of the posterior compartment of the lower leg are generally responsible for plantar flexion. The lateral and medial muscles in both…
Central and Peripheral Nervous System
The structures of the PNS are referred to as ganglia and nerves, which can be seen as distinct structures. The equivalent structures in the CNS are not obvious from this overall perspective and are best examined in prepared tissue under the…
What Is a Nucleus
(a) The nucleus of an atom contains its protons and neutrons. (b) The nucleus of a cell is the organelle that contains DNA. (c) A nucleus in the CNS is a localized center of function with the cell bodies of several neurons, shown here circled in red
Optic Nerve Versus Optic Tract
This drawing of the connections of the eye to the brain shows the optic nerve extending from the eye to the chiasm, where the structure continues as the optic tract. The same axons extend from the eye to the brain through these two bundles of fibers,…
Somatic, Autonomic, and Enteric Structures of the Nervous System
Somatic structures include the spinal nerves, both motor and sensory fibers, as well as the sensory ganglia (posterior root ganglia and cranial nerve ganglia). Autonomic structures are found in the nerves also, but include the sympathetic and…
Parts of a Neuron
The major parts of the neuron are labeled on a multipolar neuron from the CNS.
Neuron Classification by Shape
Unipolar cells have one process that includes both the axon and dendrite. Bipolar cells have two processes, the axon and a dendrite. Multipolar cells have more than two processes, the axon and two or more dendrites.
Other Neuron Classifications
Three examples of neurons that are classified on the basis of other criteria. (a) The pyramidal cell is a multipolar cell with a cell body that is shaped something like a pyramid. (b) The Purkinje cell in the cerebellum was named after the scientist…
Glial Cells of the CNS
The CNS has astrocytes, oligodendrocytes, microglia, and ependymal cells that support the neurons of the CNS in several ways.
Glial Cells of the PNS
The PNS has satellite cells and Schwann cells.
The Process of Myelination
Myelinating glia wrap several layers of cell membrane around the cell membrane of an axon segment. A single Schwann cell insulates a segment of a peripheral nerve, whereas in the CNS, an oligodendrocyte may provide insulation for a few separate axon…
Testing the Water
(1) The sensory neuron has endings in the skin that sense a stimulus such as water temperature. The strength of the signal that starts here is dependent on the strength of the stimulus. (2) The graded potential from the sensory endings, if strong…
The Sensory Input
Receptors in the skin sense the temperature of the water.
The Motor Response
On the basis of the sensory input and the integration in the CNS, a motor response is formulated and executed.
Cell Membrane and Transmembrane Proteins
The cell membrane is composed of a phospholipid bilayer and has many transmembrane proteins, including different types of channel proteins that serve as ion channels.
Ligand-Gated Channels
When the ligand, in this case the neurotransmitter acetylcholine, binds to a specific location on the extracellular surface of the channel protein, the pore opens to allow select ions through. The ions, in this case, are cations of sodium, calcium,…
Voltage-Gated Channels
Voltage-gated channels open when the transmembrane voltage changes around them. Amino acids in the structure of the protein are sensitive to charge and cause the pore to open to the selected ion.
Leakage Channels
In certain situations, ions need to move across the membrane randomly. The particular electrical properties of certain cells are modified by the presence of this type of channel.
Graded Potentials
Graded potentials are temporary changes in the membrane voltage, the characteristics of which depend on the size of the stimulus. Some types of stimuli cause depolarization of the membrane, whereas others cause hyperpolarization. It depends on the…
The Synapse
The synapse is a connection between a neuron and its target cell (which is not necessarily a neuron). The presynaptic element is the synaptic end bulb of the axon where Ca2+ enters the bulb to cause vesicle fusion and neurotransmitter release. The…
Receptor Types
(a) An ionotropic receptor is a channel that opens when the neurotransmitter binds to it. (b) A metabotropic receptor is a complex that causes metabolic changes in the cell when the neurotransmitter binds to it (1). After binding, the G protein…
Early Embryonic Development of Nervous System
The neuroectoderm begins to fold inward to form the neural groove. As the two sides of the neural groove converge, they form the neural tube, which lies beneath the ectoderm. The anterior end of the neural tube will develop into the brain, and the…
Primary and Secondary Vesicle Stages of Development
The embryonic brain develops complexity through enlargements of the neural tube called vesicles; (a) The primary vesicle stage has three regions, and (b) the secondary vesicle stage has five regions.
Spinal Bifida
(a) Spina bifida is a birth defect of the spinal cord caused when the neural tube does not completely close, but the rest of development continues. The result is the emergence of meninges and neural tissue through the vertebral column. (b) Fetal…
The Cerebrum
The cerebrum is a large component of the CNS in humans, and the most obvious aspect of it is the folded surface called the cerebral cortex.
Lobes of the Cerebral Cortex
The cerebral cortex is divided into four lobes. Extensive folding increases the surface area available for cerebral functions.
Brodmann's Areas of the Cerebral Cortex
Brodmann mapping of functionally distinct regions of the cortex was based on its cytoarchitecture at a microscopic level.
Frontal Section of Cerebral Cortex and Basal Nuclei
The major components of the basal nuclei, shown in a frontal section of the brain, are the caudate (just lateral to the lateral ventricle), the putamen (inferior to the caudate and separated by the large white-matter structure called the internal…
The Diencephalon
The diencephalon is composed primarily of the thalamus and hypothalamus, which together define the walls of the third ventricle. The thalami are two elongated, ovoid structures on either side of the midline that make contact in the middle. The…
The Brain Stem
The brain stem comprises three regions: the midbrain, the pons, and the medulla.
The Cerebellum
The cerebellum is situated on the posterior surface of the brain stem. Descending input from the cerebellum enters through the large white matter structure of the pons. Ascending input from the periphery and spinal cord enters through the fibers of…
Cross-section of Spinal Cord
The cross-section of a thoracic spinal cord segment shows the posterior, anterior, and lateral horns of gray matter, as well as the posterior, anterior, and lateral columns of white matter
Circle of Willis
The blood supply to the brain enters through the internal carotid arteries and the vertebral arteries, eventually giving rise to the circle of Willis.
Dural Sinuses and Veins
Blood drains from the brain through a series of sinuses that connect to the jugular veins.
Cerebrospinal Fluid Circulation
The choroid plexus in the four ventricles produce CSF, which is circulated through the ventricular system and then enters the subarachnoid space through the median and lateral apertures. The CSF is then reabsorbed into the blood at the arachnoid…
Dorsal Root Ganglion
The cell bodies of sensory neurons, which are unipolar neurons by shape, are seen in this photomicrograph. Also, the fibrous region is composed of the axons of these neurons that are passing through the ganglion to be part of the dorsal nerve root…
Spinal Cord and Root Ganglion
The slide includes both a cross-section of the lumbar spinal cord and a section of the dorsal root ganglion (see also [link]) (tissue source: canine).
Nerve Structure
The structure of a nerve is organized by the layers of connective tissue on the outside, around each fascicle, and surrounding the individual nerve fibers (tissue source: simian).
Close-Up of Nerve Trunk
Zoom in on this slide of a nerve trunk to examine the endoneurium, perineurium, and epineurium in greater detail (tissue source: simian).
The Cranial Nerves
The anatomical arrangement of the roots of the cranial nerves observed from an inferior view of the brain.
Nerve Plexuses of the Body
There are four main nerve plexuses in the human body. The cervical plexus supplies nerves to the posterior head and neck, as well as to the diaphragm. The brachial plexus supplies nerves to the arm. The lumbar plexus supplies nerves to the anterior…
Receptor Classification by Cell Type
Receptor cell types can be classified on the basis of their structure. Sensory neurons can have either (a) free nerve endings or (b) encapsulated endings. Photoreceptors in the eyes, such as rod cells, are examples of (c) specialized receptor cells.…
The Tongue
The tongue is covered with small bumps, called papillae, which contain taste buds that are sensitive to chemicals in ingested food or drink. Different types of papillae are found in different regions of the tongue. The taste buds contain specialized…
The Olfactory System
(a) The olfactory system begins in the peripheral structures of the nasal cavity. (b) The olfactory receptor neurons are within the olfactory epithelium. (c) Axons of the olfactory receptor neurons project through the cribriform plate of the ethmoid…
Structures of the Ear
The external ear contains the auricle, ear canal, and tympanic membrane. The middle ear contains the ossicles and is connected to the pharynx by the Eustachian tube. The inner ear contains the cochlea and vestibule, which are responsible for audition…
Transmission of Sound Waves to Cochlea
A sound wave causes the tympanic membrane to vibrate. This vibration is amplified as it moves across the malleus, incus, and stapes. The amplified vibration is picked up by the oval window causing pressure waves in the fluid of the scala vestibuli…
Cross Section of the Cochlea
The three major spaces within the cochlea are highlighted. The scala tympani and scala vestibuli lie on either side of the cochlear duct. The organ of Corti, containing the mechanoreceptor hair cells, is adjacent to the scala tympani, where it sits…
Hair Cell
The hair cell is a mechanoreceptor with an array of stereocilia emerging from its apical surface. The stereocilia are tethered together by proteins that open ion channels when the array is bent toward the tallest member of their array, and closed…
Cochlea and Organ of Corti
a given region of the basilar membrane will only move if the incoming sound is at a specific frequency. Because the tectorial membrane only moves where the basilar membrane moves, the hair cells in this region will also only respond to sounds of this…
Frequency Coding in the Cochlea
The standing sound wave generated in the cochlea by the movement of the oval window deflects the basilar membrane on the basis of the frequency of sound. Therefore, hair cells at the base of the cochlea are activated only by high frequencies, whereas…
Linear Acceleration Coding by Maculae
The maculae are specialized for sensing linear acceleration, such as when gravity acts on the tilting head, or if the head starts moving in a straight line. The difference in inertia between the hair cell stereocilia and the otolithic membrane in…
Rotational Coding by Semicircular Canals
Rotational movement of the head is encoded by the hair cells in the base of the semicircular canals. As one of the canals moves in an arc with the head, the internal fluid moves in the opposite direction, causing the cupula and stereocilia to bend.…
The Eye in the Orbit
The eye is located within the orbit and surrounded by soft tissues that protect and support its function. The orbit is surrounded by cranial bones of the skull.
Extraocular Muscles
The extraocular muscles move the eye within the orbit.
Structure of the Eye
The sphere of the eye can be divided into anterior and posterior chambers. The wall of the eye is composed of three layers: the fibrous tunic, vascular tunic, and neural tunic. Within the neural tunic is the retina, with three layers of cells and two…
Photoreceptor
(a) All photoreceptors have inner segments containing the nucleus and other important organelles and outer segments with membrane arrays containing the photosensitive opsin molecules. Rod outer segments are long columnar shapes with stacks of…
Retinal Isomers
The retinal molecule has two isomers, (a) one before a photon interacts with it and (b) one that is altered through photoisomerization.
Comparison of Color Sensitivity of Photopigments
Comparing the peak sensitivity and absorbance spectra of the four photopigments suggests that they are most sensitive to particular wavelengths.
Ascending Sensory Pathways of the Spinal Cord
The dorsal column system and spinothalamic tract are the major ascending pathways that connect the periphery with the brain.
Auditory Brain Stem Mechanisms of Sound Localization
Localizing sound in the horizontal plane is achieved by processing in the medullary nuclei of the auditory system. Connections between neurons on either side are able to compare very slight differences in sound stimuli that arrive at either ear and…
Vestibulo-ocular Reflex
Connections between the vestibular system and the cranial nerves controlling eye movement keep the eyes centered on a visual stimulus, even though the head is moving. During head movement, the eye muscles move the eyes in the opposite direction as…
Segregation of Visual Field Information at the Optic Chiasm
Contralateral visual field information from the lateral retina projects to the ipsilateral brain, whereas ipsilateral visual field information has to decussate at the optic chiasm to reach the opposite side of the brain.
The Sensory Homunculus
A cartoon representation of the sensory homunculus arranged adjacent to the cortical region in which the processing takes place.
Topographic Mapping of the Retina onto the Visual Cortex
The visual field projects onto the retina through the lenses and falls on the retinae as an inverted, reversed image. The topography of this image is maintained as the visual information travels through the visual pathway to the cortex.
Retinal Disparity
Because of the interocular distance, which results in objects of different distances falling on different spots of the two retinae, the brain can extract depth perception from the two-dimensional information of the visual field.
Ventral and Dorsal Visual Streams
From the primary visual cortex in the occipital lobe, visual processing continues in two streams—one into the temporal lobe and one into the parietal lobe.
Corticospinal Tract
The major descending tract that controls skeletal muscle movements is the corticospinal tract. It is composed of two neurons, the upper motor neuron and the lower motor neuron. The upper motor neuron has its cell body in the primary motor cortex of…
Connections of Parasympathetic Division of the Autonomic Nervous System
Neurons from brain-stem nuclei, or from the lateral horn of the sacral spinal cord, project to terminal ganglia near or within the various organs of the body. Axons from these ganglionic neurons then project the short distance to those target…
Autonomic Varicosities
The connection between autonomic fibers and target effectors is not the same as the typical synapse, such as the neuromuscular junction. Instead of a synaptic end bulb, a neurotransmitter is released from swellings along the length of a fiber that…
Comparison of Somatic and Visceral Reflexes
The afferent inputs to somatic and visceral reflexes are essentially the same, whereas the efferent branches are different. Somatic reflexes, for instance, involve a direct connection from the ventral horn of the spinal cord to the skeletal muscle.…
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Introduction to Cancer Genomics
This is the first lecture in the Bioinformatics for Cancer Genomics 2017 workshop hosted by the Canadian Bioinformatics Workshops. This lecture is by Trevor Pugh from the Princess Margaret Cancer Centre.
For tutorials and lecture slides for this…
For tutorials and lecture slides for this…
Breast Cancer Eliminated Using Keshe Technologies - Demo by Dr.Rodrigo Vildosola
Dr. Rodrigo Vildosola explains his method for treating breast cancer using Keshe Plasma Technologies. He gives an example of how he used this with one of his patients with stunning results.
Warning: The video contains graphic images of a medical…
Warning: The video contains graphic images of a medical…
Drug Formulations
This is a tutorial/lecture on Drug Formulations. We cover some topics important for classes such as Biochemistry and Pharmacology.
Coming Off Psychiatric Drugs: A Harm Reduction Approach to Medication Withdrawal | Will Hall
Psychiatric medications can sometimes be very useful, but there is often little information or guidance when the risks and harm start to outweigh the benefits. Will Hall provides an introductory overview of how to come off psychiatric medication.…
Cancer of the Esophagus
This chapter in Cancer Concepts: A Guidebook for the Non-Oncologist presents an overview of esophageal cancer, including etiology, epidemiology, screening, pathology, staging, and treatment.
Principles of Nutrition Textbook
As we get started on our journey into the world of health and nutrition, our first focus will be to
demonstrate that nutritional science is an evolving field of study, continually being updated and
supported by research, studies, and trials.
demonstrate that nutritional science is an evolving field of study, continually being updated and
supported by research, studies, and trials.
Pharmacokinetics/ADME Of Drugs | Pharmacology Online Lecture-1 | For Upcoming D.Pharm & B.Pharm Exam
In this video , we have discussed about PHARMACOKINETICS OF DRUGS - ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION (ADME) IN BRIEF. Watch the video till the end to get complete information regarding pharmacokinetics of drugs.
Topic discussed in the…
Topic discussed in the…
Food as Medicine: Preventing and Treating the Most Common Diseases with Diet
This is Dr. Greger's 2015 live presentation. Dr. Greger has scoured the world's scholarly literature on clinical nutrition and developed this new presentation based on the latest in cutting-edge research exploring the role diet may play in…
Introduction to Genetic Disorders
This is the first lecture in the Bioinformatics of Genomic Medicine 2017 workshop hosted by the Canadian Bioinformatics Workshops. This lecture is by Michael Brudno from the Hospital for Sick Children.
For tutorials and lecture slides for this…
For tutorials and lecture slides for this…
Introduction to Financial Accounting Adapted for U.S. GAAP
AccounƟng involves a process of collecƟng, recording, and reporƟng a business’s economic acƟviƟes to users. It is oŌen called the language of business because it uses a unique vocabulary
to communicate informaƟon to decision makers. To understand…
to communicate informaƟon to decision makers. To understand…
PROJECT MANAGEMENT FOR INSTRUCTIONAL
DESIGNERS
PROJECT MANAGEMENT, INSTRUCTIONAL
DESIGNERS
DESIGNERS
Professional Web Accessibility Auditing Made Easy
Digital accessibility skills are in high demand, as the world becomes more aware of barriers in digital content that prevent some people from participating in a digital society. These are essential skills for web developers, and essential knowledge…
Mastering Strategic Management
Teaching the strategic management course can be a challenge for many professors. In most business schools, strategic management is a “capstone” course that requires students to draw on insights from various functional courses they have completed…
Principles of Management
Principles of Management is designed to meet the scope and sequence requirements of the introductory course on management. This is a traditional approach to management using the leading, planning, organizing, and controlling approach. Management is a…
The Delft Sand, Clay & Rock Cutting Model
This book gives an overview of cutting theories for the cutting of sand, clay and rock as applied in dredging engineering. In dredging engineering in general sand, clay and rock are excavated with buckets of bucket ladder dredges,…
HYDRAULICS AND ELECTRICAL CONTROL OF
HYDRAULIC SYSTEMS
Differentiate between fluid power systems and mechanical or electrical systems Differentiate between hydraulic and pneumatic systems with respect to the fluid medium employed, characteristics, capacity, performance, and cleanliness
Describe a basic…
Describe a basic…
Principles of Accounting Volume 1 Financial Accounting
Principles of Accounting is designed to meet the scope and sequence requirements of a two-semester accounting course that covers the fundamentals of financial and managerial accounting. Due to the comprehensive nature of the material, we are offering…
Building information - representationand management
This book is about the foundations and principles of building information, its representation and management. It does not tell you which software or policies to choose for representing buildings and managing the resulting information. In fact, the…
Digital Circuit Projects: An Overview of Digital
Circuits Through Implementing Integrated Circuits
- Second Edition
Digital circuits, often called Integrated Circuits or ICs, are the central building blocks of a Central Processing Unit (CPU). To understand how a computer works, it is essential to understand the digital circuits which make up the CPU. This text…
Business Plan Development Guide
This textbook and its accompanying spreadsheet templates were designed with and for students wanting a practical and easy-to-follow guide for developing a business plan. It follows a unique format that both explains what to do and demonstrates how to…
Introduction To MIPS Assembly Language
Programming
This book was written to introduce students to assembly language programming in MIPS. As with all assembly
language programming texts, it covers basic operators and instructions, subprogram calling, loading and
storing memory, program control, and…
language programming texts, it covers basic operators and instructions, subprogram calling, loading and
storing memory, program control, and…
Head and Neck Cancers
1. A variety of different malignancies fall into the category of “Head and. Neck Cancers”. This chapter focuses on upper aerodigestive tract cancer.
2. Tobacco and alcohol use and human papillomavirus infection are
common causes of head and neck…
2. Tobacco and alcohol use and human papillomavirus infection are
common causes of head and neck…
Metastatic Extramammary Paget's Disease: Pathogenesis and Novel Therapeutic Approach
Extramammary Paget's disease (EMPD) is a rare, slow-growing, cutaneous adenocarcinoma that usually originates in the anogenital area and axillae outside the mammary glands. EMPD mostly progresses slowly and is often diagnosed as carcinoma in situ;…
Clinical Procedures for Safer Patient Care
This peer reviewed e-book is a must-read for nurses and other health professionals who strive to teach with creativity and excellence in clinical settings. Each chapter presents current evidence informed educational practice knowledge. Each topic is…
An Introduction to Nutrition
Essentials of Nutrition: A Functional Approach! This book is written for students who are not majoring in nutrition, but want to learn about the fundamental aspects of nutrition and how it applies to their own lives. We have written this book with…
Brehe’s Grammar Anatomy
Brehe’s Grammar Anatomy makes grammar accessible to general and specialist readers alike. This book provides an in-depth look at beginner grammar terms and concepts, providing clear examples with limited technical jargon. Whether for academic or…
Organizational Behavior
Organizational Behavior. The text presents the theory, concepts, and applications with particular emphasis on the impact that individuals and groups can have on organizational performance and culture. An array of recurring features engages students…
Intimate Communities . Wartime Healthcare and the Birth of Modern China, 1937–1945
When China’s War of Resistance against Japan began in July 1937, it sparked an immediate health crisis throughout China. In the end, China not only survived the war but emerged from the trauma with a more cohesive population. Intimate Communities…
Building Green . Environmental Architects and the Struggle for Sustainability in Mumbai
Building Green explores the experience of environmental architects in Mumbai, one of the world’s most populous and population-dense urban areas and a city iconic for its massive informal settlements, extreme wealth asymmetries, and ecological…
Migrating into Financial Markets : How Remittances Became a Development Tool
We understand very little about the billions of dollars that flow throughout the world from migrants back to their home countries. In this rigorous and illuminating work, Matt Bakker, an economic sociologist, examines how these migrant…
The Environmental Impact of Sieben Linden Ecovillage
Environmental impact assessment is widely taught and researched, but rarely covers both lifestyle and building construction in a town or neigh-bourhood. This book provides a broad assessment of the environmental impact of the ecovillage Sieben…
Governing Extractive Industries : Politics, Histories, Ideas
The large-scale extraction of minerals, hydrocarbons, and other natural resources1has long been central to national economies and the global economy.
This has been the case in colonial and post-colonial economies alike, and the harnessing of such…
This has been the case in colonial and post-colonial economies alike, and the harnessing of such…
Undergraduate Diagnostic Imaging Fundamentals
Diagnostic Imaging principles and concepts are augmented by the presentation of images for common clinical conditions. Guiding principles related to minimizing radiation exposure and requesting the most appropriate imaging examination are…
Dredging Engineering: Special Topics
In dredging, production estimating is carried out mainly with analytical physical models of the different dredging processes. Slurry transport of settling slurries and cutting processes in sand, clay and rock are already covered in two other books by…
Logical Reasoning
The goal of this book is to improve your logical-reasoning skills. These skills are also called "critical thinking skills." They are a complex weave of abilities that help you get someone's point, generate reasons for your own point, evaluate the…
3D City Models and urban information:
Current issues and perspectives
Many urban or environmental models are defined with the objective of helping practitioners and stakeholders in their decision-making processes. Models which represent in three dimensions the geometric elements of a city are called 3D city models.…
The ESPAS e-infrastructure
Νear-Earth space is the region that extends from the middle atmosphere up to the outer radiation belts. This region is of significant interest because of its potentially undesired effects on human life and on technological systems, whose…
Personalized Medicine and Neurosurgery
The Precision Medicine Initiative, which was instituted by President Barack Obama on January 20, 2015, highlighted the importance that advances in genomics and related “-omic” approaches have
made to science and medicine, and it set the stage for…
made to science and medicine, and it set the stage for…
Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy
t Quantitative four-dimensional (4D) image reconstruction methods with respiratory and cardiac motion compensation are an active area of research in ECT imaging, including SPECT and PET. They are the extensions of three-dimensional (3D) statistical…
Communicating Medicine
The core of the present study is an investigation on eighteenth-century medical writing, particularly concerning the elaboration and the communication of medicine in reference works such as universal dictionaries of arts and sciences, medical…
Innovative Medicine : Basic Research and Development
Reactive oxygen species (ROS) are an intricate part of normal cellular physiology. In excess, however, ROS can damage all three major classes of acromolecules and compromise cell via bility. We briefl y discuss the physiology of ROS but focus on the…
Plant Medicines for Clinical Trial
Our species has always used plants as medicines, during our 200,000 year existence. This is made
obvious by the plant medicines found in mummy burials, around the world, dating back thousands
of years. Human beings evolved using plant medicines to…
obvious by the plant medicines found in mummy burials, around the world, dating back thousands
of years. Human beings evolved using plant medicines to…
Drug-Diagnostics Co-Development in Oncology
The idea of combining drugs and diagnostics in oncology is not new. When the selective estrogen-receptor modulator tamoxifen was developed in the 1970s for the treatment of breast cancer, data
on estrogen-receptor status were correlated with the…
on estrogen-receptor status were correlated with the…
Machine Learning with Radiation Oncology Big Data
Half of all cancer patients may receive radiotherapy as part of their treatment. With the wealth of diverse data generated every day in the clinic, the radiation oncology community possesses a unique advantage in harnessing these massive data with…
The Impact of Systems Medicine on Human Health and Disease
Complex diseases including diabetes, neurological disorders and cancer are results from a combination of genetic, environmental and lifestyle factors, and development of new prognostic tools for the treatment of such diseases requires a deep…
Homeostasis and Allostasis of Thyroid Function
Alterations of thyroid function, especially hypothyroidism, are exceptionally common conditions. Studies from several developed countries revealed the prevalence of subclinical and overt hypothyroidism to be between 5 and 15 % and between 1 and 10%,…
Mind-Body Medicine in Children and Adolescents
The field of mind-body medicine holds significant promise for children and adolescents. Growing recognition of the intricate connections between thought, emotion, and physiology highlights the need for new therapies that leverage inner resources and…
Mind-Body Medicine in Children and Adolescents
The field of mind-body medicine holds significant promise for children and adolescents. Growing recognition of the intricate connections between thought, emotion, and physiology highlights
the need for new therapies that leverage inner resources and…
the need for new therapies that leverage inner resources and…
Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease
The Research Defence Society (RDS) was founded in 1908 by Dr Stephen Paget, son of the eminent Victorian surgeon, Sir James Paget. Its role was to defend scientists conducting medical research using animals and to inform the public about the …
Secondary Analysis of Electronic Health Records
While wonderful new medical discoveries and innovations are in the news every day, healthcare providers continue to struggle with using information. Uncertainties and unanswered clinical questions are a daily reality for the decision makers who…
Innovative Radiopharmaceuticals in Oncology and Neurology
Personalized medicine is presented as the future of patient care. Nuclear Medicine will play a major role in the selection of patients for targeted therapies and in early therapy assessment with the investigation of phenotypes and functions using…
Rabies Symptoms, Diagnosis, Prophylaxis and Treatment
Rabies is an acute, progressive, incurable viral encephalitis found throughout the world. Despite being one of the oldest recognized pathogens, its impact remains substantial in public health, veterinary medicine, and conservation biology. Thus, it…
Mathematics for Healthcare
Appropriate mathematical tools and methodologies are critical for ensuring robust and reliable computational model predictions based on medical and healthcare data in the era of the digital health revolution (Duggal et al., 2018). Patient-specific…
Fundamentals of Microwave and RF Design
Fundamentals of Microwave and RF Design enables mastery of the essential concepts required to cross the barriers to a successful career in microwave and RF design. Extensive treatment of scattering parameters, that naturally describe power flow, and…
Microwave and RF Design : Radio Systems
Microwave and RF Design: Radio Systems is a circuits- and systems-oriented approach to modern microwave and RF systems. Sufficient details at the circuits and sub-system levels are provided to understand how modern radios are implemented. Design is…
Microwave and RF Design: Transmission Lines
Microwave and RF Design: Transmission Lines builds on the concepts of forward- and backward-traveling waves. Many examples are included of advanced techniques for analyzing and designing transmission line networks with microstrip lines primarily used…
Microwave and RF Design: Networks
Microwave and RF Design: Networks presents the tools and techniques required to analyze and design microwave and RF circuits. Because of the finite speed of light, microwave circuits must be considered to be spatially distributed and so there is not…
Microwave and RF Design: Modules
Microwave and RF Design: Modules focuses on the design of systems based on microwave modules. The use of modules has become increasingly important in RF and microwave engineering for rapidly realizing high performance microwave systems. When…
Antibody Repertoire and Graft Outcome Following Solid Organ Transplantation
In recent years, there has been vast improvement in the survival of solid organ grafts. Improved
immunosuppression has resulted in efficient control of cell-mediated immune responses and has also
mitigated the effects of HLA mismatching between the…
immunosuppression has resulted in efficient control of cell-mediated immune responses and has also
mitigated the effects of HLA mismatching between the…
Natural Antibodies in Health and Disease
Natural antibodies (NAbs) are found in normal
individuals in the absence of exogenous antigenic
stimulation. Natural antibodies rapidly recognize
and protect against pathogens that have not been
previously encountered. NAbs also cross-react…
individuals in the absence of exogenous antigenic
stimulation. Natural antibodies rapidly recognize
and protect against pathogens that have not been
previously encountered. NAbs also cross-react…
Sensory Hair Cell Death and Regeneration
Sensory hair cells are the specialized mechanosensory
receptors found in vertebrate auditory, vestibular, and lateral line organs that transduce vibratory and acoustic stimuli into the sensations of hearing and
balance. Hair cells can be damaged …
receptors found in vertebrate auditory, vestibular, and lateral line organs that transduce vibratory and acoustic stimuli into the sensations of hearing and
balance. Hair cells can be damaged …
Breaking the cycle: Attacking the malaria parasite in the liver
Plasmodium falciparum malaria remains one of the most serious health problems globally. Immunization with attenuated parasites elicits multiple cellular effector mechanisms capable of eliminating Plasmodium from the liver. However, malaria liver stage…
Lyme Disease: Recent Advances and Perspectives
he interplay between host and pathogen is a complex co-evolutionary battle of surveillance and evasion. The pathogen continuously develops mechanisms to subvert the immune response in order to establish infection while the immune system responds with…
NK Cell Subsets in Health and Disease: New Developments
Under physiological conditions, the distribution /intensity of the surface markers CD56 and CD16 (FcγRIII) defines two subsets of NK lymphocytes: the CD56bright/CD16neg-dim (generally referred to as CD56bright) population that make up about 10% of…
Applications of STEM (Science, Technology, Engineering and Mathematics) tools in microbiology of infectious diseases
Science, technology, engineering, and mathematical (STEM) tools and approaches are expected to become a critical component for the prevention, control, and eradication of animal diseases at a global scale in the near future. In the last decades the…
Biomarkers in drug hypersensitivity
Drug-induced hypersensitivity reactions play a prominent role among adverse drug effects, and constitute a major health problem. It has been suggested that up to 6% of all hospital admissions are related to these reactions. Biomarkers, especially…
Tumour Viruses
The first human tumor virus was discovered in the middle of the last century by Anthony Epstein, Bert Achong and Yvonne Barr in African pediatric patients with Burkitt’s lymphoma. To date, seven viruses -EBV, KSHV, high-risk HPV, MCPV, HBV, …
Enhancing Soil Health to Mitigate Soil Degradation
This research editorial is intended to establish the context and provide a broad overview for the Special Issue of Sustainability entitled “Enhancing Soil Health to Mitigate Soil Degradation” that was initiated in 2014 to document both the magnitude…
The Transcriptional Regulation of Memory
The formation of human memories involves a series of complicated biochemical processes many of which are not fully understood. However, recent data implicate several families of transcription factors that appear critically important in the regulation…
Advances in Hydro-Meteorological Monitoring
This book presents a reprint of the Special Issue of the journal Water dedicated to “Advances in Hydro-Meteorological Monitoring”. As we planned, as editors, this Special Issue aimed to shed light on the more recent advances in ground observations…
Dynamics of decision making: from evidence to preference and belief
At the core of the many debates throughout cognitive science concerning how decisions are made are the processes governing the time course of preference formation and decision. From perceptual choices, such as whether the signal on a radar screen…
Danger Signals Triggering Immune Response and Inflammation
The immune system detects "danger", through a series of what we now call damage associated molecular pattern molecules (DAMPs), working in concert with both positive and negative signals derived from other tissues. DAMPS also known as alarmins, are…
Non-Ordinary Mental Expressions
So-called altered states of consciousness (ASC) are an intriguing, still under-researched topic, with profound neuropsychological and epistemological implications. In the last few decades there has been increasing multidisciplinary interest in…
Platelets as immune cells in physiology and immunopathology
Are platelets cells? (Not everyone agrees, since they are non-nucleate). And if platelets are cells—which all specialists consider at the time being—are they immune cells? The issue that platelets participate in immunity is no longer debated;…
Drug Development for Parasite-Induced Diarrheal Diseases
One of the top four contributors to the global burden of disease is diarrheal infections. Intestinal parasites are major causes of morbidity and mortality associated with diarrheal diseases in both the developed and developing world. Amebiasis is…
Computers and Games for Mental Health and Well-Being
Recent years have seen important developments in the computer and game industry, including the emergence of the concept of serious games. It is hypothesized that tools such as games, virtual reality, or applications for smartphones may foster…
Medical Geology: Impacts of the Natural Environment on Public Health
B. anthracis infections in wildlife and livestock have been recognized as a critically important disease in the United States for over 200 years. Historical data on environmental, weather/climate and geographical factors that influence the occurrence…
Metals Challenged by Neutron and Synchrotron Radiation
In the past one and a half decades, neutron and synchrotron radiation techniques have come to the forefront as an excellent set of tools for the wider investigation of material structures and properties [1,2], becoming available to a large user…
Handbook of Life Course Health Development
A critical mass of research linking early life events, experiences, and exposures with adult health conditions is delineating the developmental origins of many common chronic diseases. This emerging body of life course health development (LCHD)…
Development and Application of Herbal Medicine from Marine Origin
Marine herbal medicine generally refers to the use of marine plants as original materials to develop crude drugs, or for other medical purposes. The term ‘marine plants’ usually denotes macroalgae grown between intertidal and subintertidal zones,…
Cloud-Based Benchmarking of Medical Image Analysis
This book presents the VISCERAL project benchmarks for analysis and retrieval of 3D medical images (CT and MRI) on a large scale, which used an innovative cloud-based evaluation approach where the image data were stored centrally on a cloud…
Diseases of the Abdomen and Pelvis 2018-2021: Diagnostic Imaging - IDKD Book
his open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally…
Role of health economic data in policy making and reimbursement of new medical technologies
An accelerated growth of health spending began in the 1960s exceeding the historical 4% GDP threshold. This phenomenon was noticed early on in mature market economies led by the US and during the following decades spread to many global regions.…
Drugs quality control (Theoretical foundation and practical application): The Coursebook
The Course book presents the basics of drugs quality control in accordance with regulatory documents (pharmacopoeia of Europe, USA, Japan, Russia) and new data from current scientific periodicals, monographs The features of the physical, spectral and…
A Laboratory Guide to Clinical Hematology
This is eBook will be constantly updated, edited, and reviewed as new emerging information arises.
Calcium Signaling in Human Health and Diseases
Intracellular Ca2+ signals regulate a myriad of cellular functions, ranging from short-term responses, such as excitation-contraction coupling and stimulus-secretion coupling, to long-term processes, such as proliferation, gene expression,…
Calibration/Validation of Visible Infrared Imaging Radiometers and Applications
The success of the Suomi National Polar-orbiting Partnership (NPP) brings us into a new era of
global daily Earth observations, ranging from the faintest light of human settlements and air glows, to
the dramatic events of hurricanes and forest…
global daily Earth observations, ranging from the faintest light of human settlements and air glows, to
the dramatic events of hurricanes and forest…
Cancer Care Delivery and Women's Health
Cancer care delivery refers to the multiple layers of the health care system that interact to affect outcomes for patients with cancer and the quality of that care. The factors included in the care delivery system that potentially alter outcomes…
Cancer Metabolism: Molecular Targeting and Implications for Therapy
“Metabolic reprogramming” is one of the hallmarks of cancer, and is exemplified by distinctive biochemical alterations which include enhanced glucose uptake, aerobic glycolysis and glutamine-metabolism. Clinically, the prominent feature of altered…
Carbon Fibers and Their Composite Materials
To achieve good mechanical properties of carbon fibre-reinforced polycarbonate composites, the fibre-matrix adhesion must be dialled to an optimum level. The electrolytic surface treatment of carbon fibres during their production is one of the possible…
Catalytic soot oxidation by platinum on sintered metal filters. Influence of the platinum quantity, particle size and location, and investigation of the platinum-soot contact
The great challenge for next years concerning the emission of diesel engines is to develop diesel particle filters (DPF) with catalytic regeneration systems. This work is focused on the global understanding of the diesel soot oxidation on sintered…
Influence of elevated temperatures up to 100 °C on the mechanical properties of concrete
Experiments to characterize the effects of moisture content and temperature on the mechanical properties of concrete were conducted. Based on these experiments, a new overall material model capable of predicting the mechanical behaviour of concrete…
Nutrition and Cancer
Omega-3 fatty acids (n-3 FA) may have beneficial clinical and immune-modulating effects in surgical patients. In a randomized, double-blind, prospective, placebo-controlled trial, 148 patients referred for elective colorectal cancer surgery received…
Anti-fragile ICT Systems
Modern societies cannot function without information and communications technology (ICT) systems. When ICT systems such as electronic government
(e-government) systems, e-payment infrastructures, and mobile phone networks fail,users can still access…
(e-government) systems, e-payment infrastructures, and mobile phone networks fail,users can still access…
Molecular Computing and Bioinformatics
Molecular computing and bioinformatics are two important interdisciplinary sciences that study molecules and computers. Molecular computing is a branch of computing that uses DNA, biochemistry, and molecular biology hardware, instead of traditional…
Advances in Virtual Agents and Affective Computing for the Understanding and Remediation of Social Cognitive Disorders
Recent advances in computer technologies and research now enable to simulate realistic social interaction thanks to the use of increasingly complex computer models. Virtual agents reproducing both human appearance and expressive behaviors are now…
Organic traffic control
Modern cities cannot be imagined without traffic lights controlling the road network. To handle the network's changing demands efficiently, the signal plan specification needs to be shifted from the design time to the run-time of a signal system. The…
Anatomy and Plasticity in Large-Scale Brain Models
Supercomputing facilities are becoming increasingly available in neuroscience, predominantly for simulating the dynamics of electrical activity propagating through neuronal circuits. On today's most advanced supercomputers, large-scale models can be…
Anatomy and Plasticity in Large-Scale Brain Models
Supercomputing facilities are becoming increasingly available in neuroscience, predominantly for simulating the dynamics of electrical activity propagating through neuronal circuits. On today's most advanced supercomputers, large-scale models can be…
Google Earth Engine Applications
The Google Earth Engine (GEE) is a cloud computing platform designed to store and process
huge data sets (at petabyte-scale) for analysis and ultimate decision making [1]. Following the free
availability of Landsat series in 2008, Google archived…
huge data sets (at petabyte-scale) for analysis and ultimate decision making [1]. Following the free
availability of Landsat series in 2008, Google archived…
Multi-Agent Systems
Multi-agent systems (MAS) allow and promote the development of distributed and intelligent applications in complex and dynamic environments. Applications of this kind have a crucial role in our everyday life, as witnessed by the broad range of…
Entropy in Image Analysis
Image analysis is playing a very essential role in numerous research areas in the fields of science
and technology, ranging from medical imaging to the computer science of automatic vision. Being
involved in several applications, which are mainly…
and technology, ranging from medical imaging to the computer science of automatic vision. Being
involved in several applications, which are mainly…
Flexible Electronics: Fabrication and Ubiquitous Integration
Flexible Electronics platforms are increasingly used in the fields of sensors, displays, and energy conversion with the ultimate goal of facilitating their ubiquitous integration in our daily lives. Some of the key advantages associated with flexible…
Communicating Medicine
This study investigates eighteenth-century medical writing, particularly concerning the elaboration and the communication of medicine in such reference works as universal dictionaries of arts and sciences, medical dictionaries, and handbooks. Most of…
Nano/Micro-Assisted Regenerative Medicine
Regenerative medicine is an emerging multidisciplinary field that aims to repair and restore the normal functions of tissues and organs damaged by aging, disease, injury, or congenital disorders. The basic concept of "Nano/Micro-Assisted Regenerative…
Precision Medicine in Oncology
The emerging precision medicine approach aims to tailor disease prevention and treatment to each patient on the basis of individual variability, environmental factors and lifestyle. Fundamental achievements in the last few decades have converged to…
The Poetics and Politics of Alzheimer’s Disease Life-Writing
The introduction gives an overview on sociopolitical and research-related developments regarding dementia, and attempts explanations for why the interest in dementia of critical scholarship continues to be very limited and particularly focused on…
Travel Medicine - Series 1
This collection of papers describes the recent development of travel health and vaccination services delivered by pharmacists. It is the first dedicated collection of its type and provides a template for the continued growth of pharmacy practice in…
Galectins in Cancer and Translational Medicine
In the post-genomic era, many efforts have been devoted to better understanding the biological information encoded by the cell “glycome” in normal and pathologic conditions. The glycan signature of human cells plays a pivotal role in regulating…
Anatomy Quizbook: for students studying or intending to study medicine
Anatomy Quizbook is an interactive learning book that will help students and tutors – indeed anyone interested in anatomy – learn, test and improve their knowledge of the human body.Readers are presented with carefully selected questions and diagrams…
Principles and Practice of Case-based Clinical Reasoning Education
This volume describes and explains the educational method of Case-Based Clinical Reasoning (CBCR) used successfully in medical schools to prepare students to think like doctors before they enter the clinical arena and become engaged in patient care.…
White Paper on Joint Replacement: Status of Hip and Knee Arthroplasty Care in Germany
This White Paper details the status of hip and knee arthroplasty care in Germany. Hip and knee replacements are amongst the most frequently performed procedures and usually become necessarily due to age-related wear of the joint, osteoarthritis and…
Technologies for Development: From Innovation to Social Impact
This open access book presents 18 case studies that explore current scientific and technological efforts to address global development issues, such as poverty, from a holistic and interdisciplinary point of view, putting actual impacts at the centre…
Compartment Syndrome
Compartment syndrome is a complex physiologic process with significant potential harm, and though an important clinical problem, the basic science and research surrounding this entity remains poorly understood. This unique open access book fills the…
X-Ray Contrast Media: Overview, Use and Pharmaceutical Aspects
This open access book is an overview on CT/X-ray contrast media designed for radiologists and other medical specialists who use contrast media in imaging and interventional procedures as well as related scientists on the use and pharmaceutical…
Surgical Ophthalmic Oncology
Designed as an easy-to-use, practical guide to tumors of the eye, lids, and orbit, this open access book comprehensively addresses surgical treatment and management of diseases related to ophthalmic oncology. Surgical Ophthalmic Oncology: A…
Technologies for Development: From Innovation to Social Impact
This open access book presents 18 case studies that explore current scientific and technological efforts to address global development issues, such as poverty, from a holistic and interdisciplinary point of view, putting actual impacts at the centre…
Clinical Text Mining: Secondary Use of Electronic Patient Records
This open access book describes the results of natural language processing and machine learning methods applied to clinical text from electronic patient records.It is divided into twelve chapters. Chapters 1-4 discuss the history and background of…
Consideration of Abiotic Natural Resources in Life Cycle Assessments
The book contains a collection of articles dealing with how the extraction of mineral resources can be considered in environmental analyses such as Life Cycle Assessment (LCA). The consumption of resources, e.g., metals, is increasing strongly…
Habitats and Biota of the Gulf of Mexico: Before the Deepwater Horizon Oil Spill: Volume 1: Water Quality, Sediments, Sediment Contaminants, Oil and Gas Seeps, Coastal Habitats, Offshore Plankton and Benthos, and Shellfish
The Gulf of Mexico is an open and dynamic marine ecosystem rich in natural resources but heavily impacted by human activities, including agricultural, industrial, commercial and coastal development. The Gulf of Mexico has been continuously exposed to…
Metals Challenged by Neutron and Synchrotron Radiation
Neutron and Synchrotron radiation methods have matured to become powerful techniques for the study of a vast range of materials, including metals. The characterization methods comprise the categories of diffraction, spectroscopy and imaging, which…
Sustainable Manufacturing: Challenges, Solutions and Implementation Perspectives
This edited volume presents the research results of the Collaborative Research Center 1026 “Sustainable manufacturing - shaping global value creation”. The book aims at providing a reference guide of sustainable manufacturing for researchers,…
Agricultural Implications of the Fukushima Nuclear Accident
Following the Fukushima nuclear accident, a large volume of monitoring data has been collected about the soil, air, dust, and seawater, along with data about an immense number of foods supplied to the market. Little is known, however, about the…
Marginality: Addressing the Nexus of Poverty, Exclusion and Ecology
This book takes a new approach on understanding causes of extreme poverty and promising actions to address it. Its focus is on marginality being a root cause of poverty and deprivation. “Marginality” is the position of people on the edge, preventing…
Model-Driven Development and Operation of Multi-Cloud Applications: The MODAClouds Approach
This book summarizes work being undertaken within the collaborative MODAClouds research project, which aims to facilitate interoperability between heterogeneous Cloud platforms and remove the constraints of deployment, portability, and reversibility…
Sustainable Land Use and Rural Development in Southeast Asia: Innovations and Policies for Mountainous Areas
This book is based on the findings of a long-term (2000-2014) interdisciplinary research project of the University of Hohenheim in collaboration with several universities in Thailand and Vietnam. Titled Sustainable Land Use and Rural Development in…
Wetlands and Water Framework Directive
This book compares the lessons learned from a wetland-perspective approach to the changing climate and the requirements of the Water Framework Directive (WFD) with regard to environmental conservation. Examples from Germany and Poland are discussed…
Reflections on the Fukushima Daiichi Nuclear Accident: Toward Social-Scientific Literacy and Engineering Resilience
This book focuses on nuclear engineering education in the post-Fukushima era. It was edited by the organizers of the summer school held in August 2011 in University of California, Berkeley, as part of a collaborative program between the University of…
Biodiversity of Vegetable Crops, A Living Heritage
Intensive agriculture has generally resulted in higher productivity, but also in a trend towards decreasing levels of agro-biodiversity, which represents a key point in ensuring the adaptability and resilience of agro-ecosystems in the global…
Bioeconomy: Shaping the Transition to a Sustainable, Biobased Economy
This book defines the new field of "Bioeconomy" as the sustainable and innovative use of biomass and biological knowledge to provide food, feed, industrial products, bioenergy and ecological services. The chapters highlight the importance of…
Protocols for Pre-Field Screening of Mutants for Salt Tolerance in Rice, Wheat and Barley
This book offers effective, low-cost and user-friendly protocols for the pre-field selection of salt-tolerant mutants in cereal crops. It presents simple methods for measuring soil salinity, including soil sampling and the analysis of water-soluble…
Changing Land Use, Changing Livelihoods: Smallholders Today
his book brings together eleven works by scholars within and beyond geography, to argue the case for a continued engagement with smallholder agricultural studies. The research detailed is largely empirical and draws on a wide spectrum of mixed…
Power Transformer Diagnostics, Monitoring and Design Features
Power transformers are key components in electric power distribution and transmission systems, and it is essential that they function properly for many years. With increasing age, there are potential risks of extremely high monetary losses due to…
Micro/Nano Devices for Chemical Analysis
Since the concept of micro total analysis systems (µ-TAS) has been advocated, various kinds of micro/nano devices have been developed by researchers in many fields, such as in chemistry, chemical engineering, mechanical engineering, electric…
UAV‐Based Remote Sensing Volume 1
Active technological development has fuelled rapid growth in the number of Unmanned Aerial Vehicle (UAV) platforms being deployed around the globe. Novel UAV platforms, UAV-based sensors, robotic sensing and imaging techniques, the development of…
UAV‐Based Remote Sensing Volume 2
ctive technological development has fuelled rapid growth in the number of Unmanned Aerial Vehicle (UAV) platforms being deployed around the globe. Novel UAV platforms, UAV-based sensors, robotic sensing and imaging techniques, the development of…
Marine Geomorphometry
Geomorphometry is the science of quantitative terrain characterization and analysis, and has traditionally focused on the investigation of terrestrial and planetary landscapes. However, applications of marine geomorphometry have now moved beyond the…
Two-Dimensional Electronics - Prospects and Challenges
During the past 10 years, two-dimensional materials have found incredible attention in the scientific community. The first two-dimensional material studied in detail was graphene, and many groups explored its potential for electronic applications.…
UAV or Drones for Remote Sensing Applications
The rapid development and growth of unmanned aerial vehicles (UAVs) as a remote sensing platform, as well as advances in the miniaturization of instrumentation and data systems, have resulted in an increasing uptake of this technology in the…
UAV or Drones for Remote Sensing Applications
The rapid development and growth of unmanned aerial vehicles (UAVs) as a remote sensing platform, as well as advances in the miniaturization of instrumentation and data systems, have resulted in an increasing uptake of this technology in the…
Open-Source Electronics Platforms
Open-source electronics are becoming very popular, and are integrated with our daily educational and developmental activities. At present, the use open-source electronics for teaching science, technology, engineering, and mathematics (STEM) has…
Civil Engineering and Symmetry
A topic of utmost importance in civil engineering is finding optimal solutions throughout the life cycle of buildings and infrastructural objects, including their design, manufacturing, use, and maintenance. Operational research, management science,…
Engineering Dielectric Liquid Applications
Dielectric liquids are used as impregnates of solid insulations or filling products in many kinds of equipment, such as transformers (power, rectifier, distribution, traction, furnace, potential, current), resistors, reactors, capacitors, cables,…
The Emerging Discipline of Quantitative Systems Pharmacology
In 2011, the National Institutes of Health (NIH), in collaboration with leaders from the pharmaceutical industry and the academic community, published a white paper describing the emerging discipline of Quantitative Systems Pharmacology (QSP), and…
Structural Health Monitoring (SHM) of Civil Structures
At the current time of writing, the American Society of Civil Engineers (ASCE) has awarded American infrastructure a grade of D+, meaning poor and at risk. Part of the reason for the low grade is due to the rapid deterioration of structural integrity…
Applications of Power Electronics
Power electronics technology is still an emerging technology, and it has found its way into many applications, from renewable energy generation (i.e., wind power and solar power) to electrical vehicles (EVs), biomedical devices, and small appliances,…
Applications of Power Electronics
Power electronics technology is still an emerging technology, and it has found its way into many applications, from renewable energy generation (i.e., wind power and solar power) to electrical vehicles (EVs), biomedical devices, and small appliances,…
Power Transformer Diagnostics, Monitoring and Design Features
Power transformers are key components in electric power distribution and transmission systems, and it is essential that they function properly for many years. With increasing age, there are potential risks of extremely high monetary losses due to…
T Cell Regulation by the Environment
Naïve T cells get activated upon encounter with their cognate antigen and differentiate into a specific subset of effector cells. These T cells are themselves plastic and are able to re-differentiate into another subset, changing both phenotype and…
Fulfilling the Promise of Technology Transfer
Universities and research institutes are increasingly expected to contribute to society by creating innovation from the returns of their research results and the establishment of new technologies. Toward that goal, Keio University in Japan held an…
Epigenetics of B Cells and Antibody Responses
Epigenetics is the study of changes in gene activity that are heritable but not caused by changes in the DNA sequence. By modulating gene activities, epigenetic changes regulate cell functions. They include DNA methylation, histone posttranslational…
Rangeland Systems: Processes, Management and Challenges
This book provides an unprecedented synthesis of the current status of scientific and management knowledge regarding global rangelands and the major challenges that confront them. It has been organized around three major themes. The first summarizes…
Graphene-Polymer Composites
Presenting very high surface-to-volume ratio, relatively simple processability and low cost, graphene and graphene-related materials were soon identified as promising nanofillers for polymer matrixes. Reports have shown notorious property…
Sustainable Smart Cities and Smart Villages Research
a. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms.[There is ever more research on smart cities and new interdisciplinary approaches proposed…
Engineering Dielectric Liquid Applications
Dielectric liquids are used as impregnates of solid insulations or filling products in many kinds of equipment, such as transformers (power, rectifier, distribution, traction, furnace, potential, current), resistors, reactors, capacitors, cables,…
Groundwater Contamination and Remediation
This Special Issue of Water brings together 10 studies on groundwater contamination and remediation. Common themes include practical techniques for plume identification and delineation, the central role of subsurface processes, the pervasiveness of…
Understanding and Managing Emerald Ash Borer Impacts on Ash Forests
The emerald ash borer (EAB) is rapidly spreading throughout Eastern North America and devastating ecosystems where ash is a component tree. This rapid and sustained loss of ash trees has already resulted in ecological impacts on both terrestrial and…
Optical Methods in Sensing and Imaging for Medical and Biological Applications
The recent advances in optical sources and detectors have opened up new opportunities for sensing and imaging techniques which can be successfully used in biomedical and healthcare applications. This book, entitled ‘Optical Methods in Sensing and…
Electromagnetic Technologies for Medical Diagnostics. Fundamental Issues, Clinical Applications and Perspectives
The content of this Special Issue will highlight papers exploring non-commutative Fourier harmonic analysis, spectral properties of aperiodic order, the hypoelliptic heat equation, and the relativistic heat equation in the context of Information…
Advanced Asphalt Materials and Paving Technologies
There has been significant research progress in the area of pavement materials and paving technologies in the past decade. This includes the use of warm mix asphalt technologies, rubber asphalt, bio asphalt, nanomaterial applications, new…
Advances in Integrated Energy Systems Design, Control and Optimization
In the face of climate change and resource scarcity, energy supply systems are on the verge of a major transformation, which mainly includes the introduction of new components and their integration into the existing infrastructures, new network…
Advances in Water Distribution Networks
The Special Issue on Advances in Water Distribution Networks (WDNs) explores four important topics of research in the framework of WDNs, namely simulation and optimization modelling, topology and partitioning, water quality, and service…
Aeroacustic and Vibroacoustic Advancement in Aerospace and Automotive Systems
The purpose of this special issue is to highlight the latest advances in vibroacoustics and aeroacoustics applied to aerospace and automotive industries. In proposing this wide topic, we wanted to give scientists and engineers the opportunity to…
Applications of Power Electronics
Power electronics technology is still an emerging technology, and it has found its way into many applications, from renewable energy generation (i.e., wind power and solar power) to electrical vehicles (EVs), biomedical devices, and small appliances,…
Applications of Power Electronics
Power electronics technology is still an emerging technology, and it has found its way into many applications, from renewable energy generation (i.e., wind power and solar power) to electrical vehicles (EVs), biomedical devices, and small appliances,…
Assistance Robotics and Biosensors
This Special Issue is focused on breakthrough developments in the field of biosensors, as well as on the current scientific progress in biomedical signal processing. The papers address innovative solutions in assistance robotics based on…
Biofuel and Bioenergy Technology
The subject of this book is ""Biofuel and Bioenergy Technology"". It aims to publish high-quality review and research papers, addressing recent advances in biofuel and bioenergy. State-of-the-art studies of advanced techniques of biorefinery for…
Civil Engineering and Symmetry
A topic of utmost importance in civil engineering is finding optimal solutions throughout the life cycle of buildings and infrastructural objects, including their design, manufacturing, use, and maintenance. Operational research, management science,…
Control and Nonlinear Dynamics on Energy Conversion Systems
The ever-increasing need for higher efficiency, smaller size, and lower cost make the analysis, understanding, and design of energy conversion systems extremely important, interesting, and even imperative. One of the most neglected features in the…
The Delft Sand, Clay and Rock Cutting Model
Sand, clay and rock have to be excavated for a variety of purposes, such as dredging, trenching, mining (including deep sea mining), drilling, tunnel boring and many other applications. Many excavations take place on dry land, but they are also…
Sustainable Living with Environmental Risks
We are not free from environmental risks that accompany the development of human societies. Modern economic development has accelerated environmental pollution, caused loss of natural habitats, and modified landscapes. These environmental changes…
Design and Applications of Coordinate Measuring Machines
Coordinate measuring machines (CMMs) have been conventionally used in industry for 3-dimensional and form-error measurements of macro parts for many years. Ever since the first CMM, developed by Ferranti Co. in the late 1950s, they have been regarded…
Development and Application of Optical Coherence Tomography (Oct)
This special feature issue has been initiated to celebrate the 25th anniversary of Optical Coherence Tomography (OCT). In OCT, broad bandwidth light is used in order to produce cross sectional images of turbid and translucent samples with high axial…
Development and Application of Nonlinear Dissipative Device in Structural Vibration Control
This book entitled Development and Application of Nonlinear Dissipative Device in Structural Vibration Control contains contributions that focus on the development and application of innovative nonlinear dissipative systems that mitigate the…
Consideration of Abiotic Natural Resources in Life Cycle Assessments
Consideration of Abiotic Natural Resources in Life Cycle Assessments
Marine Geomorphometry
Geomorphometry is the science of quantitative terrain characterization and analysis, and has traditionally focused on the investigation of terrestrial and planetary landscapes. However, applications of marine geomorphometry have now moved beyond the…
Advances in Welding Metal Alloys, Dissimilar Metals and Additively Manufactured Parts
Welding technology has been taken for granted as a mature and established technology for too long. However, many new welding technologies have been included among the alternatives to joining materials. They come both from the areas of fusion and…
Aluminum Alloys
Aluminium is the world’s most abundant metal and is the third most common element, comprising 8% of the Earth’s crust. The versatility of aluminium makes it the most widely used metal after steel. By utilising various combinations of their…
First-Principles Approaches to Metals, Alloys, and Metallic Compounds
Current fundamental electronic-structure theory allows for the accurate prediction and characterization of elemental metals adopting any allotropic structure, intermetallic compounds, and other metal-rich phases. From an engineering perspective,…
Hydrometallurgy
Hydrometallurgy, which involves the use of aqueous solutions for the recovery of metals from ores, concentrates, and recycled or residual material, plays an integral role in the multi-billion dollar minerals processing industry. There are numerous…
Metals Challenged by Neutron and Synchrotron Radiation
Neutron and Synchrotron radiation methods have matured to become powerful techniques for the study of a vast range of materials, including metals. The characterization methods comprise the categories of diffraction, spectroscopy and imaging, which…
Shape Memory Alloys 2017
Shape memory alloys (SMAs) have special property of the shape memory effect. After thermal treatment above the martensitic transition temperature, the alloys come back to the original shape when the alloys heat again after having cooled it to the…
Advances in Production Technology
This edited volume contains the selected papers presented at the scientific board meeting of the German Cluster of Excellence on “Integrative Production Technology for High-Wage Countries”, held in November 2014. The topical structure of the book is…
Interface Oral Health Science 2014
The Tohoku University Graduate School of Dentistry first introduced the concept of “Interface Oral Health Science”, designed to establish and maintain healthy oral cavities, which are home to a number of mixed systems. Included in those systems are:…
Safer Healthcare: Strategies for the Real World
The authors of this book set out a system of safety strategies and interventions for managing patient safety on a day-to-day basis and improving safety over the long term. These strategies are applicable at all levels of the healthcare system from…
Beyond Safety Training: Embedding Safety in Professional Skills
This book investigates why, despite more and more resources devoted to safety training, expectations are not entirely met, particularly in the industrial sectors that have already achieved a high safety level. It not only reflects the most precious…
Protocols for Pre-Field Screening of Mutants for Salt Tolerance in Rice, Wheat and Barley
This book offers effective, low-cost and user-friendly protocols for the pre-field selection of salt-tolerant mutants in cereal crops. It presents simple methods for measuring soil salinity, including soil sampling and the analysis of water-soluble…
Compartment Syndrome
Compartment syndrome is a complex physiologic process with significant potential harm, and though an important clinical problem, the basic science and research surrounding this entity remains poorly understood. This unique open access book fills the…
X-Ray Contrast Media: Overview, Use and Pharmaceutical Aspects
his open access book is an overview on CT/X-ray contrast media designed for radiologists and other medical specialists who use contrast media in imaging and interventional procedures as well as related scientists on the use and pharmaceutical aspects…
Ocean-Atmosphere Interactions of Gases and Particles
The oceans and atmosphere interact through various processes, including the transfer of momentum, heat, gases and particles. In this book leading international experts come together to provide a state-of-the-art account of these exchanges and their…
Public Health Ethics: Cases Spanning the Globe
his Open Access book highlights the ethical issues and dilemmas that arise in the practice of public health. It is also a tool to support instruction, debate, and dialogue regarding public health ethics. Although the practice of public health has…
Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology
his volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics…
Cosmic Ray Neutron Sensing: Estimation of Agricultural Crop Biomass Water Equivalent
This open access book provides methods for the estimation of Biomass Water Equivalent (BEW), an essential step for improving the accuracy of area-wide soil moisture by cosmic-ray neutron sensors (CRNS). Three techniques are explained in detail: (i)…
Counteracting Urban Heat Island Effects in a Global Climate Change Scenario
Urban heat islands are a new type of microclimatic phenomenon that causes a significant increase in the temperature of cities compared to surrounding areas. The phenomenon has been enforced by the current trend towards climate change. Although…
Sustainable Living with Environmental Risks
We are not free from environmental risks that accompany the development of human societies. Modern economic development has accelerated environmental pollution, caused loss of natural habitats, and modified landscapes. These environmental changes…
Designing Sustainable Energy for All: Sustainable Product-Service System Design Applied to Distributed Renewable Energy
This open access book addresses the issue of diffusing sustainable energy access in low- and middle-income contexts. Access to energy is one of the greatest challenges for many people living in low-income and developing contexts, as around 1.4…
Designing Sustainable Technologies, Products and Policies
This open access book provides insight into the implementation of Life Cycle approaches along the entire business value chain, supporting environmental, social and economic sustainability related to the development of industrial technologies,…
Contemporary Bioethics: Islamic Perspective
This book combines Islamic textual analysis with juridical methodology to engage dominant secular bioethics in the Muslim healthcare institutions. It integrates Islamic textual resources with medical information in order to provide careful analyses…
High Density Lipoproteins: From Biological Understanding to Clinical Exploitation
this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on…
Autonomous Driving: Technical, Legal and Social Aspects
This book takes a look at fully automated, autonomous vehicles and discusses many open questions: How can autonomous vehicles be integrated into the current transportation system with diverse users and human drivers? Where do automated vehicles fall…
Genome Editing in Neurosciences
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology,…
Finance for Food
This book reflects the current state of discussion about agricultural and rural finance in developing and transition countries. It provides insight into specific themes, such as commodity value chains, farm banking and risk management in agricultural…
Freshwater Microplastics: Emerging Environmental Contaminants?
This volume focuses on microscopic plastic debris, also referred to as microplastics, which have been detected in aquatic environments around the globe and have accordingly raised serious concerns. The book explores whether microplastics represent…
Human Anatomy Lab Manual
This is a lab manual for a college-level human anatomy course. Mastery of anatomy requires a fair amount of memorization and recall skills. The activities in this manual encourage students to engage with new vocabulary in many ways, including…
Non-Vitamin K Antagonist Oral Anticoagulants: A Concise Guide
This book is an essential guide to the medical treatment of thrombosis and presents core principles of anticoagulant therapeutics as well as drug recommendations. Written by recognized experts in the field, this concise, accessible handbook provides…
Surgical Infections
urgical infections are caused by the breakdown of the equilibrium existing between organisms and the host. This may occur after a breach in a protective surface, as occurs after surgical trauma, changes in host resistance, or particular…
High Density Lipoproteins: From Biological Understanding to Clinical Exploitation
this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge…
Fulfilling the Promise of Technology Transfer
Universities and research institutes are increasingly expected to contribute to society by creating innovation from the returns of their research results and the establishment of new technologies. Toward that goal, Keio University in Japan held an…
Biotechnologies for Plant Mutation Breeding: Protocols
This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by…
Marginality: Addressing the Nexus of Poverty, Exclusion and Ecology
This book takes a new approach on understanding causes of extreme poverty and promising actions to address it. Its focus is on marginality being a root cause of poverty and deprivation. “Marginality” is the position of people on the edge, preventing…
The Sustainability of Agro-Food and Natural Resource Systems in the Mediterranean Basin
This book is focused on the challenges to implement sustainability in diverse contexts such as agribusiness, natural resource systems and new technologies. The experiences made by the researchers of the School of Agricultural, Forestry, Food and…
The Impact of Food Bioactives on Health: In Vitro and Ex Vivo Models
Infogest' (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture. Infogest aims at building an open international network of institutes undertaking…
Responsible Innovation: Ethics, Safety and Technology
This textbook is based on the MOOC Responsible Innovation offered by the TU Delft. It provides a framework to reflect on the ethics and risks of new technologies. How can we make sure that innovations do justice to social and ethical values? How can…
Actuarial and Financial Risks in Life Insurance, Pensions and Household Finance
The recent regulatory changes, together with the increasing awareness of the variety of sources of uncertainty that affect the activities of insurance and pension funds, have generated increasing attention towards insurance risk management theory and…
Advances in Production Technology
This edited volume contains the selected papers presented at the scientific board meeting of the German Cluster of Excellence on “Integrative Production Technology for High-Wage Countries”, held in November 2014. The topical structure of the book is…
Benchmarking Eventually Consistent Distributed Storage Systems
Cloud storage services and NoSQL systems typically offer only ""Eventual Consistency"", a rather weak guarantee covering a broad range of potential data consistency behavior. The degree of actual (in-)consistency, however, is unknown. This work…
Building Evacuation with Mobile Devices
The rapidly growing world population and increasingly dense settlements demand ever-larger and more complex buildings from today's engineers. In comparison to this technological progress, a building's equipment for emergency evacuation has been…
A Celebration of the Ties That Bind Us: Connections Between Actuarial Science and Mathematical Finance
The articles in this volume are contributed by scholars who are not only experts in areas of Actuarial Science (AS) and Mathematical Finance (MF), but also those who present diverse perspectives from both industry and academia. Topics from multiple…
Science and Technology Governance and Ethics: A Global Perspective from Europe, India and China
This book analyzes the possibilities for effective global governance of science in Europe, India and China. Authors from the three regions join forces to explore how ethical concerns over new technologies can be incorporated into global science and…
Ship and Offshore Structure Design in Climate Change Perspective
This book summarizes results of longstanding research and scientific contributions from many projects and relevant working groups. It collects and evaluates wind and wave climate projections under changing climate having design needs and marine…
Sustainable Living with Environmental Risks
We are not free from environmental risks that accompany the development of human societies. Modern economic development has accelerated environmental pollution, caused loss of natural habitats, and modified landscapes. These environmental changes…
High Density Lipoproteins: From Biological Understanding to Clinical Exploitation
this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on…
Dynamic Capacity Control in Air Cargo Revenue Management
This book studies air cargo capacity control problems. The focus is on analyzing decision models with intuitive optimal decisions as well as on developing efficient heuristics and bounds. Three different models are studied: First, a model for…
Dynamics of Long-Life Assets: From Technology Adaptation to Upgrading the Business Model
The editors present essential methods and tools to support a holistic approach to the challenge of system upgrades and innovation in the context of high-value products and services. The approach presented here is based on three main pillars: an…
Econometrics and Income Inequality
This Special Issue is devoted to the econometric analysis of income inequality and income distributions. Given the recent surge of inequality research, this Special Issue seeks to combine both theoretical and applied contributions which advance the…
Economics of Distributed Storage Systems : an economic analysis of arbitrage-maximizing storage systems at the end consumer level
Increasing the shares of Renewable Energy Sources (RES) and Distributed Energy Resources (DER) is one of the most important levers in many countries to cope with the environmental, political, and economic challenges of future energy supply. The…
Fulfilling the Promise of Technology Transfer
Universities and research institutes are increasingly expected to contribute to society by creating innovation from the returns of their research results and the establishment of new technologies. Toward that goal, Keio University in Japan held an…
Extreme Values and Financial Risk
Since the 2008 financial crisis, modeling of the extreme values of financial risk has become important. Postgraduate programs and PhD research programs in mathematical finance are cropping up in nearly every university. Additionally, many conferences…
Indicator-based Sustainability Assessment of the German Energy System and its Transition
The energy transition not only has an impact on technical infrastructures but also leads to socio-economic changes. To evaluate the sustainability aspects of the German Energiewende, the authors have developed a monitoring system which includes 45…
Information Management and Market Engineering. Vol. II
The research program Information Management and Market Engineering focuses on the analysis and the design of electronic markets. Taking a holistic view of the conceptualization and realization of solutions, the research integrates the disciplines…
Information Management and Market Engineering. [Vol. I]
The research program �Information Management and Market Engineering� focuses on the analysis and the design of electronic markets. Taking a holistic view of the conceptualization and realization of solutions, the research integrates the disciplines…
Innovation in General Purpose Technologies : How Knowledge Gains when It Is Shared
This book tackles the different aspects of the creation and transmission of knowledge in the context of the characteristics of a general purpose technology. Nanotechnology is investigated as showcase example. Particular emphasis is put on the role of…
Innovations in Quantitative Risk Management
Quantitative Finance; Game Theory, Economics, Social and Behav. Sciences; Finance/Investment/Banking; Actuarial Sciences
Intelligent Business Process Optimization for the Service Industry
The company's sustainable competitive advantage derives from its capacity to create value for customers and to adapt the operational practices to changing situations. Business processes are the heart of each company. Therefore process excellence has…
Managing Elevated Risk: Global Liquidity, Capital Flows, and Macroprudential Policy - An Asian Perspective
This book discusses the risks and opportunities that arise in Emerging Asia given the context of a new environment in global liquidity and capital flows. It elaborates on the need to ensure financial and overall economic stability in the region…
Market engineering. A structured design process for electronic markets
In this book, the author provides a complete process for electronic markets design together with the required en-gineering methods. As such the book is unique applying tech-niques from engineering design to modern Information Systems and Economics.…
Microfinance, EU Structural Funds and Capacity Building for Managing Authorities: A Comparative Analysis of European Convergence Regions
In recent years, the European Commission has attached increasing importance to the use of financial engineering instruments rather than traditional grant-based financing for the microcredit sector, considering these to be the most efficient option…
Optics in Our Time
Light and light based technologies have played an important role in transforming our lives via scientific contributions spanned over thousands of years. In this book we present a vast collection of articles on various aspects of light and its…
Modeling and Selection of Software Service Variants
Providers and consumers have to deal with variants of software services, which are alternative instances of a services design, implementation, deployment, or operation. This work develops the service feature modeling language to represent software…
Moral Reasoning at Work: Rethinking Ethics in Organizations
Moral dilemmas are a pervasive feature of working life. Moral Reasoning at Work offers a fresh perspective on how to live with them. How do we cope with situations where no matter what we decide to do, something will be wrong? How do we live with the…
Ontology Alignment using Biologically-inspired Optimisation Algorithms
It is investigated how biologically-inspired optimisation methods can be used to compute alignments between ontologies. Independent of particular similarity metrics, the developed techniques demonstrate anytime behaviour and high scalability. Due to…
Organic Service-Level Management in Service-Oriented Environments
Dynamic service-oriented environments (SOEs) are characterised by a large number of heterogeneous service components that are expected to support the business as a whole. The present work provides a negotiation-based approach to facilitate automated…
Performance and Behavior of Family Firms
Family involvement characterizes a large number of firms around the world and is thought to significantly impact their strategies, behavior, and performance. Family involvement occurs when a family exerts control over the firm through ownership and…
Poverty Reduction Policies and Practices in Developing Asia
This book looks at the major policy challenges facing developing Asia and how the region sustains rapid economic growth to reduce multidimensional poverty through socially inclusive and environmentally sustainable measures. Asia is facing many…
Process Measurement in Business Process Management : Theoretical Framework and Analysis of Several Aspects
Process measurement deals with the quantification of business process models using process model metrics. This book presents a theoretical framework for the prediction of external process model attributes (as, for example, error-proneness and…
Production cost models with regard to liberalised electricity markets
This book makes a contribution to the formulation and implementation of production cost models for the modelling of liberalized electricity markets by addressing issues associated with the level of detail in the representation of the underlying power…
Promoting Social Dialogue in European Organizations: Human Resources Management and Constructive Conflict Management
This volume focuses on describing the social dialogue system in organizations from an Human Resources Management perspective. Based on the NEIRE model for industrial relations, key factors are determined contributing to creative social dialogue in…
Quality in Design and Execution of Engineering Practice
Quality in Design and Execution of Engineering Practice is about quality management focused at fitness for purpose, rather than compliance with specifications, rules and regulations. The focus on getting execution in line with fitness for purpose is…
Global Business Strategy: Multinational Corporations Venturing into Emerging Markets
This book presents theories and case studies for corporations in developed nations, including Japan, for designing strategies to maximize opportunities and minimize threats in business expansion into developing nations. The case studies featured here…
Risk Analysis and Portfolio Modelling
Financial Risk Measurement is a challenging task, because both the types of risk and the techniques evolve very quickly. This book collects a number of novel contributions to the measurement of financial risk, which address either non-fully explored…
Risk Measures with Applications in Finance and Economics
Risk measures play a vital role in many subfields of economics and finance. It has been proposed that risk measures could be analysed in relation to the performance of variables extracted from empirical real-world data. For example, risk measures may…
Role and dynamics of 'Late-comers' in the global technology competition
Faster developing cycles and economic developments created many emerging economies in the 20th century. For sustainable economic growth, however, the construction and constant preservation of a profound knowledge base and technological pool is…
Stochastics of Environmental and Financial Economics
These Proceedings offer a selection of peer-reviewed research and survey papers by some of the foremost international researchers in the fields of finance, energy, stochastics and risk, who present their latest findings on topical problems. The…
Strategic power plant investment planning under fuel and carbon price uncertainty
The profitability of power plant investments depends strongly on uncertain fuel and carbon prices. In this doctoral thesis, we combine fundamental electricity market models with stochastic dynamic programming to evaluate power plant investments under…
Subject-Oriented Business Process Management
Activities performed in organizations are coordinated via communication between the people involved. The sentences used to communicate are naturally structured by subject, verb, and object. The subject describes the actor, the verb the action and the…
Sustainable Business Models
The dynamically changing world economy, in an era of intensive development and globalization, creates new needs in both the theoretical models of management and in the practical discussion related to the perception of business. Because of new…
Sustainable Human Resource Management
The concept of sustainability is important for companies both in the case of SMEs and worldwide multinational companies. Some key factors to help a company achieve its sustainability objectives are based on human resource management. Sustainable…
Innovations in Derivatives Markets: Fixed Income Modeling, Valuation Adjustments, Risk Management, and Regulation
his book presents 20 peer-reviewed chapters on current aspects of derivatives markets and derivative pricing. The contributions, written by leading researchers in the field as well as experienced authors from the financial industry, present the state…
Web-oriented Event Processing
How can the Web be made situation-aware? Event processing is a suitable technology for gaining the necessary real-time results. The Web, however, has many users and many application domains. Thus, we developed multi-schema friendly data models…
Managing the Complexity of Critical Infrastructures: A Modelling and Simulation Approach
This book summarizes work being pursued in the context of the CIPRNet (Critical Infrastructure Preparedness and Resilience Research Network) research project, co-funded by the European Union under the Seventh Framework Programme (FP7). The project is…
Governance for Drought Resilience: Land and Water Drought Management in Europe
This book presents the findings of a team of scientists and practitioners who have been working on the project “Benefits of Governance in Drought Adaptation” (in short: the DROP project), which is included in the European Union’s INTERREG IVB NWE…
High Mountain Conservation in a Changing World
This book aims to provide case studies and a general view of the main processes involved in the ecosystem shifts occurring in the high mountains, and to analyse the implications for nature conservation. Although case studies from the Pyrenees are…
Evolution, Monitoring and Predicting Models of Rockburst: Precursor Information for Rock Failure
This open access book focuses on investigating predicting precursor information and key points of rockburst in mining engineering through laboratory experiment, theoretical analysis, numerical simulation and case studies. Understanding the evolution…
Innovative Medicine: Basic Research and Development
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long…
Integrated Groundwater Management
The aim of this book is to document for the first time the dimensions and requirements of effective integrated groundwater management (IGM). Groundwater management is a formidable challenge, one that remains one of humanity’s foremost priorities. It…
Biotechnologies for Plant Mutation Breeding: Protocols
This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by…
Stem Cells in Neuroendocrinology
This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in…
Methods for Measuring Greenhouse Gas Balances and Evaluating Mitigation Options in Smallholder Agriculture
This book provides standards and guidelines for quantifying greenhouse gas emissions and removals in smallholder agricultural systems and comparing options for climate change mitigation based on emission reductions and livelihood trade-offs.…
Nature-Based Solutions to Climate Change Adaptation in Urban Areas: Linkages between Science, Policy and Practice
This book brings together research findings and experiences from science, policy and practice to highlight and debate the importance of nature-based solutions to climate change adaptation in urban areas. Emphasis is given to the potential of…
The Handbook of Salutogenesis
This in-depth survey of salutogenesis shows the breadth and strengths of this innovative perspective on health promotion, health care, and wellness. Background and historical chapters trace the development of the salutogenic model of health, and…
Hormones, Metabolism and the Benefits of Exercise
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to…
Perspectives on European Earthquake Engineering and Seismology: Volume 2
This book collects 4 keynote and 15 theme lectures presented at the 2nd European Conference on Earthquake Engineering and Seismology (2ECEES), held in Istanbul, Turkey, from August 24 to 29, 2014. The conference was organized by the Turkish…
Plant Selection for Bioretention Systems and Stormwater Treatment Practices
As cities develop, more land is converted into impervious surfaces, which do not allow water to infiltrate. Careful urban planning is needed to ensure that the hydrologic cycle and water quality of the catchment areas are not affected. There are…
Self-Reported Population Health: An International Perspective based on EQ-5D
The EQ-5D instrument, as a standardized, cross-culturally validated measure of self-assessed health has a hugely important role in understanding population health within and across countries. Over the past two decades a wealth of international…
Clinical Text Mining: Secondary Use of Electronic Patient Records
This open access book describes the results of natural language processing and machine learning methods applied to clinical text from electronic patient records. It is divided into twelve chapters. Chapters 1-4 discuss the history and background of…
Cognitive Supervision for Robot-Assisted Minimally Invasive Laser Surgery
This thesis lays the groundwork for the automatic supervision of the laser incision process, which aims to complement surgeons’ perception of the state of tissues and enhance their control over laser incisions. The research problem is formulated as…
Ecological Risk Assessment for Chlorpyrifos in Terrestrial and Aquatic Systems in North America
This book attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological…
MARE-WINT: New Materials and Reliability in Offshore Wind Turbine Technology
This book provides a holistic, interdisciplinary overview of offshore wind energy, and is a must-read for advanced researchers. Topics, from the design and analysis of future turbines, to the decommissioning of wind farms, are covered. The scope of…
Satellite Earth Observations and Their Impact on Society and Policy
he result of a workshop bringing together an international advisory board of experts in science, satellite technologies, industry innovations, and public policy, this book addresses the current and future roles of satellite Earth observations in…
A Time for Metabolism and Hormones
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the…
Nicotinic Acetylcholine Receptor Signaling in Neuroprotection
This open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating…
Tuberculosis in Adults and Children
This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of…
The Impact of Food Bioactives on Health: In Vitro and Ex Vivo Models
Infogest' (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture. Infogest aims at building an open international network of institutes undertaking…
Wetlands and Water Framework Directive
This book compares the lessons learned from a wetland-perspective approach to the changing climate and the requirements of the Water Framework Directive (WFD) with regard to environmental conservation. Examples from Germany and Poland are discussed…
Eating, Drinking: Surviving
This publication addresses the global challenges of food and water security in a rapidly changing and complex world. The essays highlight the links between bio-physical and socio-cultural processes, making connections between local and global scales,…
Resilience: A New Paradigm of Nuclear Safety: From Accident Mitigation to Resilient Society Facing Extreme Situations
This book summarizes presentations and discussions from the two-day international workshop held at UC Berkeley in March 2015, and derives questions to be addressed in multi-disciplinary research toward a new paradigm of nuclear safety. The…
Non-Equilibrium Social Science and Policy: Introduction and Essays on New and Changing Paradigms in Socio-Economic Thinking
The overall aim of this book, an outcome of the European FP7 FET Open NESS project, is to contribute to the ongoing effort to put the quantitative social sciences on a proper footing for the 21st century. A key focus is economics, and its…
Abiotic Stress Effects on Performance of Horticultural Crops
Horticultural crop yield and quality depend on genotype, environmental conditions, and production management. In particular, adverse environmental conditions may greatly affect crop performance, reducing crop yield by 50%–70%. Abiotic stresses such…
Acoustic and Elastic Waves: Recent Trends in Science and Engineering
The present Special Issue intends to explore new directions in the field of acoustics and ultrasonics. The interest includes, but is not limited to, the use of acoustic technology for condition monitoring of materials and structures. Topics of…
Actuarial and Financial Risks in Life Insurance, Pensions and Household Finance
The recent regulatory changes, together with the increasing awareness of the variety of sources of uncertainty that affect the activities of insurance and pension funds, have generated increasing attention towards insurance risk management theory and…
Acupuncture – Basic Research and Clinical Application
This book focuses on the investigation, development, and modernization of acupuncture in basic research settings as well as in clinical applications. The book contains 13 chapters reporting the latest evidence-based results of acupuncture research…
Adaptive Catchment Management and Reservoir Operation
River catchments and reservoirs play a central role in water security, food supply, flood risk management, hydropower generation, and ecosystem services; however, they are now under increasing pressure from population growth, economic activities, and…
Additive Manufacturing Technologies and Applications
The present Special Issue proposes articles in the area of Additive Manufacturing with particular attention to the different employed technologies and the several possible applications. The main investigated technologies are the Selective Laser…
Advanced Applications for Smart Energy Systems Considering Grid-Interactive Demand Response
This book covers applied research on smart energy systems, smart grids, smart energy homes, smart energy products and services, and the advanced applications thereof, in the context of demand response and grid interactions. In particular, this book…
Advanced Asphalt Materials and Paving Technologies
There has been significant research progress in the area of pavement materials and paving technologies in the past decade. This includes the use of warm mix asphalt technologies, rubber asphalt, bio asphalt, nanomaterial applications, new…
Advanced DSP Techniques for High-Capacity and Energy-Efficient Optical Fiber Communications
The rapid proliferation of the Internet has been driving communication networks closer and closer to their limits, while available bandwidth is disappearing due to an ever-increasing network load. Over the past decade, optical fiber communication…
Advanced Hydroinformatic Techniques for the Simulation and Analysis of Water Supply and Distribution Systems
The overall objective of this Special Issue is to improve knowledge on developing and using advanced simulation tools in water supply and distribution systems. The final aim is to propose a suitable framework supporting insightful hydraulic…
Advanced Memristor Modeling: Memristor Circuits and Networks
The investigation of new memory schemes, neural networks, computer systems, and many other improved electronic devices is very important for the future generation’s electronic circuits and for their widespread application in all the areas of…
Advances in Airborne Lidar Systems and Data Processing
Presented to audience as “Airborne Laser Systems and Data Processing”, this book collects the
papers in the Remote Sensing special issue “ Airborne Laser Scanning” (November 2016) and several
other papers selected from recent, previous Remote…
papers in the Remote Sensing special issue “ Airborne Laser Scanning” (November 2016) and several
other papers selected from recent, previous Remote…
Advances in Catalyst Deactivation
Catalyst deactivation, the loss over time of catalytic activity and/or selectivity, is a problem of great and continuing concern in the practice of industrial catalytic processes. Costs to industry for catalyst replacement and process shutdown total…
Advances in Environmental Engineering
The book presents research papers addressing a wide range of environmental topics: water and wastewater treatment and management, soil degradation and conservation, sediment pollution control, environmental impacts of technologies, life cycle…
Advances in Groundwater Flow and Solute Transport: Pushing the Hidden Boundary
In recent decades, the study of groundwater flow and solute transport has advanced into new territories that are beyond conventional theories, such as Darcy’s law and Fick’s law. The studied media have changed from permeable porous and fractured ones…
Advances in Micro-Bioreactor Design for Organ Cell Studies
Micro-bioreactors offer unique opportunities to study biological systems under fluidic conditions. The concept of micro-bioreactors suggests that biological reaction conditions on a large scale can be scaled down to micro-volumes while maintaining…
Advances in Multi-Sensor Information Fusion: Theory and Applications 2017
The information fusion technique can integrate a large amount of data and knowledge representing the same real-world object and obtain a consistent, accurate and useful representation of that object. The data may be independent or redundant, and can…
Application of Artificial Neural Networks in Geoinformatics
Recently, a need has arisen for prediction techniques that can address a variety of problems by combining methods from the rapidly developing field of machine learning with geoinformation technologies such as GIS, remote sensing, and GPS. As a…
Application of Bioinformatics in Cancers
This collection of 25 research papers comprised of 22 original articles and 3 reviews is brought together from international leaders in bioinformatics and biostatistics. The collection highlights recent computational advances that improve the ability…
Applications of Computational Intelligence to Power Systems
Electric power systems around the world are changing in terms of structure, operation, management and ownership due to technical, financial, and ideological reasons. Power systems keep on expanding in terms of geographical areas, asset additions, and…
Applications of Remote Sensing/ GIS in Water Resources and Flooding Risk Managements
Remote sensing and GIS play critical roles in water resource and flood inundation mapping and risk management. Remote sensing provides data sources for mapping water resources (snow and glaciers, water bodies, soil moisture and groundwater),…
Applications of Semiconductor Optical Amplifiers
ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. [Semiconductor optical amplifiers (SOAs) are considered a key enabling technology for the…
Assistance Robotics and Biosensors
This Special Issue is focused on breakthrough developments in the field of biosensors, as well as on the current scientific progress in biomedical signal processing. The papers address innovative solutions in assistance robotics based on…
Beverage Consumption Habits around the World: Association with Total Water and Energy Intakes
Fluid intake has barely been assessed, and hydration status has only rarely been measured in epidemiological studies. This hampers attempts to assess the adequacy of water intake at a population level. However, although guidelines have been…
Bio-Inspired Robotics
Modern robotic technologies have enabled robots to operate in a variety of unstructured and dynamically-changing environments, in addition to traditional structured environments. Robots have, thus, become an important element in our everyday lives.…
Biocatalysis and Pharmaceuticals: A Smart Tool for Sustainable Development
Biocatalysis, that is, the use of biological catalysts (enzymes, cells, etc.) for the preparation of highly valuable compounds is undergoing a great development, being considered an extremely sustainable approach to undertaking environmental demands.…
Bioconversion Processes
Compared to conventional chemical technologies and other similar industrial processes, bioprocesses represent a more sustainable and environmentally-friendly alternative for the production of fuels and platform chemicals. In biorefineries, different…
Biodiversity and Conservation in Forests
Global forest communities cover only about 30% of land areas, but they provide important ecosystem services, such as watershed protection, carbon sequestration, and oxygen production, as well as renewable forest products for human subsistence and…
Biodiversity of Vegetable Crops, A Living Heritage
Intensive agriculture has generally resulted in higher productivity, but also in a trend towards decreasing levels of agro-biodiversity, which represents a key point in ensuring the adaptability and resilience of agro-ecosystems in the global…
BioEnergy and BioChemicals Production from Biomass and Residual Resources
Research and technology developments in bioenergy and biochemical production systems are of the utmost importance for the development of next generation, highly efficient biomass conversion concepts, maximizing the total energy and chemical output.…
The Biology and Treatment of Myeloid Leukaemias
There has been an observed decrease in the global mortality from cancer, mostly atributable to improved, particularly early, detection and prevention. For many carcinomas and leukaemias in adults, once the disease has reached a certain stage there…
Biomass for Energy Country Specific Show Case Studies
In many domestic and industrial processes, vast percentages of primary energy are produced by the combustion of fossil fuels. Apart from diminishing the source of fossil fuels and the increasing risk of higher costs and energy security, the impact on…
Biotechnological Applications of Phage and Phage-Derived Proteins
Phages have shown a high biotechnological potential with numerous applications. The advent of high-resolution microscopy techniques aligned with omic and molecular tools have revealed innovative phage features and enabled new processes that can be…
Cadmium Sources and Toxicity
Cadmium (Cd) is an environmental toxicant of continuing public health concern worldwide, because total diet studies have shown that Cd is present in virtually all foodstuffs. Consequently, foods that are frequently consumed in large quantities, such…
Cancer Biomarkers and Targets in Digestive Organs
Identification and development of cancer biomarkers and targets have greatly accelerated progress towards precision medicine in oncology. Studies of tumor biology have not only provided insights into the mechanisms underlying carcinogenesis, but also…
Carbon Capture and Storage
Climate change is one of the main threats to modern society. This phenomenon is associated with an increase in greenhouse gas (GHGs, mainly carbon dioxide—CO2) emissions due to anthropogenic activities. The main causes are the burning of fossil fuels…
Carbon, Nitrogen and Phosphorus Cycling in Forest Soils
The majority of carbon stored in the soils of the world is stored in forests. The refractory nature of some portions of forest soil organic matter also provides the slow, gradual release of organic nitrogen and phosphorus to sustain long term forest…
Catalysts Deactivation, Poisoning and Regeneration
Catalyst lifetime represents one of the most crucial economic aspects in industrial catalytic processes, due to costly shutdowns, catalyst replacements, and proper disposal of spent materials. Not surprisingly, there is considerable motivation to…
Chemical and Molecular Approach to Tumor Metastases
Dear Colleagues, Malignant tumors develop distant metastases, e.g., small clusters of cells that detach from the primitive site and colonize distant organs and tissues. Unlike the primary masses, metastases are often difficult to fully eradicate by…
Clean Energy and Fuel (Hydrogen) Storage
Clean energy and fuel storage are often required for both stationary and automotive applications. Some of these clean energy and fuel storage technologies currently under extensive research and development include hydrogen storage, direct electric…
Climate Change Mitigation and Adaptation—ZEMCH 2016
This book explores the current issues around sustainable design and energy efficiency within the construction industry in both developed and developing countries. Sustainable housing; thermal comfort; daylighting; low-income housing; green roofs;…
Climate Variability and Climate Change Impacts on Land Surface, Hydrological Processes and Water Management
During the last several decades, Earth´s climate has undergone significant changes due to anthropogenic global warming, and feedbacks to the water cycle. Therefore, persistent efforts are required to improve our understanding of hydrological…
Communication in Pharmacy Practice
This reprint book ‘Communication in Pharmacy Practice’ is launched to help improve communication practices by increasing knowledge of different aspects of communication in pharmacy practice. The book consists of recently published research articles…
Competence Training for Pharmacy
The educational system leading up to the pharmacy degree, student training, and the continuing personal development of pharmacists are being more and more mapped to the competences pharmacists require to provide the relevant safe and efficient…
Computational Methods of Multi-Physics Problems
This book offers a collection of six papers addressing problems associated with the computational modeling of multi-field problems. Some of the proposed contributions present novel computational techniques, while other topics focus on applying…
Control and Nonlinear Dynamics on Energy Conversion Systems
The ever-increasing need for higher efficiency, smaller size, and lower cost make the analysis, understanding, and design of energy conversion systems extremely important, interesting, and even imperative. One of the most neglected features in the…
Current Strategies for the Biochemical Diagnosis and Monitoring of Mitochondrial Disease
Mitochondrial disease constitutes a complex and heterogeneous group of disorders resulting from a defect in mitochondrial respiratory chain (MRC) enzyme activity. In view of the dual regulation of the MRC, exercised by both the mitochondrial and…
Design and Applications of Coordinate Measuring Machines
Coordinate measuring machines (CMMs) have been conventionally used in industry for 3-dimensional and form-error measurements of macro parts for many years. Ever since the first CMM, developed by Ferranti Co. in the late 1950s, they have been regarded…
Development and Application of Herbal Medicine from Marine Origin
Marine herbal medicine generally refers to the use of marine plants as original materials to develop crude drugs, or for other medical purposes. The term ‘marine plants’ usually denotes macroalgae grown between intertidal and subintertidal zones,…
Development and Application of Nonlinear Dissipative Device in Structural Vibration Control
This book entitled Development and Application of Nonlinear Dissipative Device in Structural Vibration Control contains contributions that focus on the development and application of innovative nonlinear dissipative systems that mitigate the…
DHA for Optimal Health
his Special Issue of Nutrients, entitled "DHA for Optimal Health", consists of evidence-based original research or reviews of the scientific literature. Manuscripts focus on the evidence that underpins dietary requirements throughout the lifespan…
Diagnosis and Management of Pediatric Diseases
A screenshot of some the most rapidly evolving fields in Neonatology and Pediatrics with articles reviewing some metabolic dysregulations as well as non-oncologic diseases that may occur in infancy, childhood, youth. The illustrative material with…
Diagnosis and Treatment of Thoracic Outlet Syndrome
Thoracic outlet syndrome (TOS) is a spectrum of disorders resulting from the compression of the neurovascular structures within the thoracic outlet. The three main subtypes of TOS are defined by the anatomic structure affected by the extrinsic…
Diagnosis of Neurogenetic Disorders: Contribution of Next Generation Sequencing and Deep Phenotyping
The contribution of genomic variants to the aetiopathogenesis of both paediatric and adult neurological disease is being increasingly recognized. The use of next-generation sequencing has led to the discovery of novel neurodevelopmental disorders, as…
Diet and Metabolic Dysfunction (2)
The purpose of these books is to have an updated systematic overview examining, in detail, the functional role of different diets and dietary components in maintaining glucose homeostasis and preventing long-term complications. The first book…
Dietary Intake and Behavior in Children
Dietary intake in children is not only associated with current and future health, but also with behavior and learning. Especially during early childhood and throughout the school-age years, adequate food and nutrient intake to support brain…
Design and analysis of a content-based image retrieval system
The automatic retrieval of images according to the similarity of their content is a challenging task with many application fields. In this book the automatic retrieval of images according to human spontaneous perception without further effort or…
Design for Stability in Transport Logistics - Definition, Concepts and Evaluation
Lean management describes a set of methods combined with a management philosophy which aims at eliminating waste in logistics processes. In production logistics, lean is already widespread and applied successfully. Research has shown that lean also…
Determining Cycle Times for Packing in Distribution Centres
Scope of this work is to determine cycle time formulas for packing in distribution centres. No such formulas exist today, even if it is the second most important process after picking. Based on examining packing, morphological boxes showing time…
Discrete time analysis of batch processes in material flow systems
Scope of this work is the development of appropriate models for the evaluation of batch processes in material flow systems. The presented analytical methods support the long range planning in an early planning stage, in which capacities are…
Discrete Time Analysis of Multi-Server Queueing Systems in Material Handling and Service
In this doctoral thesis, performance parameters of multi-server queueing systems are estimated under general stochastic assumptions. We present an exact calculation method for the discrete time distribution of the number of customers in the queueing…
Distributed Transformers for Broadband Monolithic Millimeter-Wave Integrated Power Amplifiers
This work presents methods and techniques to optimize and implement distributed magnetic transformers for their application in matching networks of Monolithic Millimeter-wave Integrated Circuits (MMICs). It describes strategies for the efficiency and…
Divertor Development for a Future Fusion Power Plant
Nuclear fusion is considered as a future source of sustainable energy supply. Since the H-mode discovery in ASDEX experiment ""Divertor I"" in 1982, the divertor has been an integral part of all modern tokamaks and stellarators. The major goal of…
ECG Imaging of Ventricular Activity in Clinical Applications
ECG imaging was performed in humans to reconstruct ventricular activation patterns and localize their excitation origins. The precision of the non-invasive reconstructions was evaluated against invasive measurements and found to be in line with the…
ECG Based Analysis of the Ventricular Repolarisation in the Human Heart
ECG recordings provide diagnostic relevant information on the de- and repolarisation sequences of the heart. A modification of the repolarisation sequence is assumed to cause Torsades de Pointes. Especially drug induced effects on the repolarisation…
Economics of Distributed Storage Systems : an economic analysis of arbitrage-maximizing storage systems at the end consumer level
Increasing the shares of Renewable Energy Sources (RES) and Distributed Energy Resources (DER) is one of the most important levers in many countries to cope with the environmental, political, and economic challenges of future energy supply. The…
Electrofiltration of Biopolymers : Spatially Distributed Process Analysis
In biotechnology the current downstream processing trends are directed towards integrated, faster and more effective processes. Electrofiltration is a hybrid method which is a combination of membrane filtration and electrophoresis in a dead-end…
Financial markets and public information
The last decades have seen dramatic changes in trading technology and the way that financial markets operate. As trading technology advances, news providers have kept pace and deliver news to market participants around the world within fractions of a…
Finite Element Method (FEM) Model and Performance Analysis of Solid Oxide Fuel Cells
This work presents a numerical FEM framework, capable of predicting SOFC performance under technically relevant, planar stack contacting conditions. A high level of confidence in the model predictions is supplied by using exclusively experimentally…
Flow control : theoretical concept of absolute instability
At the 37th Prandtl memorial lecture on Regions of Viccous Flow, H.Oertel 1994 developed for the first time the stability theory of local perturbations in boundary layers and wake flows, as well as their practical application in the flow control of…
Fluid Flow and Heat Transfer in Cellular Solids
To determine the characteristics and properties of cellular solids for an application, and to allow a systematic practical use by means of correlations and modelling approaches, we perform experimental investigations and develop numerical methods. In…
Formation of Intracardiac Electrograms under Physiological and Pathological Conditions
This work presents methods to advance electrophysiological simulations of intracardiac electrograms (IEGM). An experimental setup is introduced, which combines electrical measurements of extracellular potentials with a method for optical acquisition…
The formation of patterns in subaqueous sediment
This book investigates the formation of subaqueous patterns by means of high-fidelity numerical simulations which resolve all the relevant scales of the flow and the sediment bed. This is required to provide a space- and time-resolved information on…
Forward and inverse problems of electrocardiography : clinical investigations
The non-invasive reconstruction of cardiac activity can significantly improve the quality of cardiac diagnostics. Two major approaches are considered. The model-based method consists in the optimization of an electrophysiological cardiac model until…
High Performance Light Water Reactor : Design and Analyses
The High Performance Light Water Reactor is a nuclear reactor concept of the 4th generation which is cooled and moderated with supercritical water. The concept has been worked out by a consortium of European partners, co-funded by the European…
High Temperature Superconductor Cable Concepts for Fusion Magnets
Three concepts of high temperature superconductor cables carrying kA currents (RACC, CORC and TSTC) are investigated, optimized and evaluated in the scope of their applicability as conductor in fusion magnets. The magnetic field and temperature…
The impact of interfaces on the performance of organic photovoltaic cells
Organic photovoltaic is an attractive technology to solve future energy supply scenarios. To further increase the potential of this technology novel absorber materials and interface materials have to be developed. In this work the paramount…
Improving the Spectral Bandwidth of Superconducting Nanowire Single-Photon Detectors (SNSPDs)
This work presents a comprehensive investigation of the influence of geometry-dependent factors on performance metrics of superconducting single-photon detectors. With fundamental knowledge, main investigations are focused to extend the spectral…
Information Management and Market Engineering. Vol. II
The research program Information Management and Market Engineering focuses on the analysis and the design of electronic markets. Taking a holistic view of the conceptualization and realization of solutions, the research integrates the disciplines…
Information Management and Market Engineering. [Vol. I]
The research program �Information Management and Market Engineering� focuses on the analysis and the design of electronic markets. Taking a holistic view of the conceptualization and realization of solutions, the research integrates the disciplines…
Geothermal Energy: Delivering on the Global Potential
After decades of being largely the preserve of countries in volcanic regions, the use of geothermal energy—for both heat and power applications—is now expanding worldwide. This reflects its excellent low-carbon credentials and its ability to offer…
Glassy Materials Based Microdevices
Abstract
Microtechnology has changed our world since the last century, when silicon microelectronics revolutionized sensor, control and communication areas, with applications extending from domotics to automotive, and from security to biomedicine.…
Microtechnology has changed our world since the last century, when silicon microelectronics revolutionized sensor, control and communication areas, with applications extending from domotics to automotive, and from security to biomedicine.…
Global Indigeneities and the Environment
Global Indigeneities and the Environment—covering fields from American Indian Studies, anthropology, communications, ethnoecology, ethnomusicology, geography, global studies, history, and literature, the purpose of the Special Issue is to give new…
Gluten Related Disorders: People Shall not Live on Bread Alone
Once upon a time, gluten was not part of the human diet, and therefore, there were no gluten-related disorders. With the advent of agriculture 10,000 years ago, the introduction of gluten-containing grains in the human diet created conditions for…
Gluten-Free Diet
In the last few years, an increasing number of individuals have adopted a gluten free diet (GFD). A significant proportion of that includes patients affected by celiac disease (CD), who have to follow a strict GFD for medical purposes. However, a…
Grain-based Foods: Processing, Properties, and Heath Attributes
The Special Issue aims to provide a complete exploration of the scientific principles related to processing, fermentation/malting, and nutrition of cereal grains. It also describes their physical and chemical characteristics and explains how these…
Heat and Mass Transfer in Building Energy Performance Assessment
The building industry is influenced by many factors and trends reflecting the current situation and developments in social, economic, technical, and scientific fields. One of the most important trends seeks to minimize the energy demand. This can be…
Heat Transfer Processes in Oscillatory Flow Conditions
Heat exchange processes in steady flows have been studied extensively over the last two hundred years, and are now a part of undergraduate syllabi in most engineering courses. However, heat transfer processes in oscillatory flow conditions are still…
Hillslope and Watershed Hydrology
Watershed hydrology is driven by climate forcing, near ground surface characteristics, and human activities, addressing a wide spectrum of environmental and water resource problems regarding both scientific-driven questions and practical engineering…
Human and Animal Sensitivity: How Stock-People and Consumer Perception Can Affect Animal Welfare
This book presents cross-discipline studies covering aspects ranging from animal science to social/consumer sciences and psychology, with the aim to collect and disseminate information promoting the continuous enhancement of animal welfare by…
Human Factors in Green Building
World Green Building Council suggests that health, well-being and productivity should be the next chapter for green building. There is an obvious shift of green building movement from technology-centric towards human-centric, which culminates in…
Humidity Sensors. Advances in Reliability, Calibration and Application
Humidity detection has deep significance for the scientific research surrounding medical care and human performance, and the industrial development of agriculture, geography and automated instruments. This special issue aims to showcase some of the…
Identification and Characterization of Antimicrobial Peptides with Therapeutic Potential
Antimicrobial peptides are key defense molecules adopted by all life forms to prevent infection. They also have other beneficial effects such as boosting immune response, anticancer, and wound healing. The antiviral effects of antimicrobial peptides…
Impact of Bioactive Peptides on Human Health
Food-derived bioactive peptides or dietary peptides are increasingly becoming recognized as major food compounds for human health promotion, which prevent the occurrence of chronic diseases through their impacts on the gastrointestinal,…
Innovation Issues in Water, Agriculture and Food
In a worldwide context of ever-growing competition for water and land, climate change, droughts and man-made water scarcity, and less-participatory water governance, agriculture faces the great challenge of producing enough food for a continually…
Innovative Extraction Techniques and Hyphenated Instrument Configuration for Complex Matrices Analysis
The present Special Issue, “Innovative Extraction Techniques and Hyphenated Instrument Configuration for Complex Matrices Analysis”, aims to collect and to disseminate some of the most significant and recent contributions in the interdisciplinary…
Innovative Technologies and Services for Smart Cities
A smart city is a modern technology-driven urban area which uses sensing devices, information, and communication technology connected to the internet of things (IoTs) for the optimum and efficient utilization of infrastructures and services with the…
The Insecticidal Bacterial Toxins in Modern Agriculture
Increased awareness about environmental adverse effects of human activities has prompted the use of insecticides with low impact on systems associated to agriculture. Currently, the most successful biological products are based on protein toxins from…
Integral Transforms and Operational Calculus
Researches and investigations involving the theory and applications of integral transforms and operational calculus are remarkably wide-spread in many diverse areas of the mathematical, physical, chemical, engineering and statistical sciences.
Integrated Role of Nutrition and Physical Activity for Lifelong Health
As computer and space technologies have been developed, geoscience information systems (GIS) and remote sensing (RS) technologies, which deal with the geospatial information, have been rapidly maturing. Moreover, over the last few decades, machine…
Integration of 2D Materials for Electronics Applications
Two-dimensional (2D) materials and their vertical/lateral heterostructures are currently the subject of massive research interests, both for fundamental science and for technological applications in diverse fields, such as electronics,…
Interface Circuits for Microsensor Integrated Systems
this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. [Recent advances in sensing technologies, especially those for Microsensor Integrated Systems, have led…
Kernel Methods and Hybrid Evolutionary Algorithms in Energy Forecasting
The development of kernel methods and hybrid evolutionary algorithms (HEAs) to support experts in energy forecasting is of great importance to improving the accuracy of the actions derived from an energy decision maker, and it is crucial that they…
Landscape Urbanism and Green Infrastructure
This volume examines the applicability of landscape urbanism theory in contemporary landscape architecture practice by bringing together ecology and architecture in the built environment. Using participatory planning of green infrastructure and…
Life Cycle Assessment on Green Building Implementation
Greenhouse-gas emissions have become one of the most impacting environmental issues in today’s society. A rapidly increasing trend in global CO2emissions particularly since the early nineties (23.64% since 1990) has led to the generation of about…
Liquid Crystal on Silicon Devices: Modeling and Advanced Spatial Light Modulation Applications
Liquid Crystal on Silicon (LCoS) has become one of the most widespread technologies for spatial light modulation in optics and photonics applications. These reflective microdisplays are composed of a high-performance silicon complementary metal oxide…
Machine Learning and Embedded Computing in Advanced Driver Assistance Systems (ADAS)
This book contains the latest research on machine learning and embedded computing in advanced driver assistance systems (ADAS). It encompasses research in detection, tracking, LiDAR
Machine Learning Techniques Applied to Geoscience Information System and Remote Sensing
As computer and space technologies have been developed, geoscience information systems (GIS) and remote sensing (RS) technologies, which deal with the geospatial information, have been rapidly maturing. Moreover, over the last few decades, machine…
Machining—Recent Advances, Applications and Challenges
The Special Issue Machining—Recent Advances, Applications and Challenges is intended as a humble collection of some of the hottest topics in machining. The manufacturing industry is a varying and challenging environment where new advances emerge from…
Magnesium Intake and Human Health
Magnesium is universally recognized as an essential nutrient for human life and health. Indeed, magnesium plays an important physiologic role in every organ of the human body. Disturbances of Mg homeostasis have been implicated in the pathophysiology…
Magnetic Materials Based Biosensors
[Selective and quantitative detection of different kinds of biocomponents plays an important role in biomedical applications, clinical diagnostics, environmental monitoring, toxicology, regenerative medicine and drug delivery. Therefore,…
Manufacturing and Surface Engineering
The desired properties of surface components include the improvement of different properties, such as aesthetic appearance, oxidation resistance, wear resistance, mechanical properties, electronic or electrical properties, thermal insulation, wear,…
Marine Compounds and Cancer
In Western countries, cancer is among the most frequent causes of death. Despite striking advances in cancer therapy, especially by the so called “targeted agents”, there is still an urgent need for new drugs in oncology. Hope comes from the marine…
The impact of interfaces on the performance of organic photovoltaic cells
Organic photovoltaic is an attractive technology to solve future energy supply scenarios. To further increase the potential of this technology novel absorber materials and interface materials have to be developed. In this work the paramount…
Indicator-based Sustainability Assessment of the German Energy System and its Transition
The energy transition not only has an impact on technical infrastructures but also leads to socio-economic changes. To evaluate the sustainability aspects of the German Energiewende, the authors have developed a monitoring system which includes 45…
Influence of fully miscible lubrication oil on flow boiling of CO? inside horizontal evaporator tubes
Flow boiling heat transfer, pressure drop and flow pattern of CO?-POE oil mixtures were experimentally investigated in smooth and micro-fin tubes. The POE oil used features full miscibility in the range of operation investigated. The experimental…
Intelligent Business Process Optimization for the Service Industry
The company's sustainable competitive advantage derives from its capacity to create value for customers and to adapt the operational practices to changing situations. Business processes are the heart of each company. Therefore process excellence has…
Magnetization of High Temperature Superconducting Trapped-Field Magnets
High temperature superconducting (HTS) bulks and stacks of coated conductors can be magnetized to become trapped-field magnets that provide much stronger magnetic fields than those reachable with conventional permanent magnets. This work investigates…
Mapping and Localization in Urban Environments Using Cameras
In this work we present a system to fully automatically create a highly accurate visual feature map from image data aquired from within a moving vehicle. Moreover, a system for high precision self localization is presented. Furthermore, we present a…
Market engineering. A structured design process for electronic markets
In this book, the author provides a complete process for electronic markets design together with the required en-gineering methods. As such the book is unique applying tech-niques from engineering design to modern Information Systems and Economics.…
Micromechanical Modeling and Simulation of Forming Processes
The deep drawing of an aluminum alloy used in the packaging industry for the beverage can manufacturing process is investigated. In this work, the effective constitutive behavior is based on a crystal plasticity model in combination with a non-linear…
Modeling of electrophysiology and tension development in the human heart
Comprehension of the beating of the human heart is important for cardiac research and will improve many clinical applications. Simulations based on models describing cardiac electro-mechanics can acquire insights into this behavior. This work focuses…
Modelling the human cardiac fluid mechanics
We present a virtual heart model simulating the flow in the left human ventricle and in the aorta. Because of the lack of in vivo structure data of the human ventricle, the active ventricle movement is given by a time-dependent ventricle model that…
Modified mass-spring system for physically based deformation modeling
Mass-spring systems are considered the simplest and most intuitive of all deformable models. They are computationally efficient, and can handle large deformations with ease. But they suffer several intrinsic limitations. In this book a modified…
Network Structures of Cargo Airlines - An Empirical and a Modelling Approach
The development of efficient air freight networks is an upcoming challenge. The present book approaches this problem for cargo airlines by characterising and classifying their network structures and by developing a model for an airline's strategic…
Numerical Haemodynamics in the Human Heart
The characteristic vortex formation in the ventricles is believed to be affected at an early stage of heart diseases. First, post-processing of patient-specific data has to be standardised. The chosen methods, a combination of Eulerian and Lagrangian…
Numerical Modeling of Stagnation Flows over Porous Catalytic Surfaces
In this book, stagnation flows on a catalytic porous plate is modeled one-dimensionally coupled with multi-step surface reaction mechanisms and molecular transport (diffusion and conduction) in the flow field and in the porous catalyst. Internal and…
Optical antennas : linear and nonlinear excitation and emission
The linear and nonlinear resonance behaviour of optical antennas (metallic nanostructures showing resonance behaviour at optical frequencies) made of gold and aluminum using electron-beam lithography is investigated. Specifically, it is of interest…
Optically Powered Highly Energy-efficient Sensor Networks
In optically powered networks, both, communication signals and power for remotely located sensor nodes, are transmitted over an optical fiber. Key features of optically powered networks are node operation without local power supplies or batteries as…
Optimization of Hot-Electron Bolometers for THz Radiation
Hot-electron bolometers are fast and low noise radiation detectors which can be used for many different applications. The aim of this work was to optimize the fabrication process of hot-electron bolometers and gain a deeper understanding of the…
Organic Semiconductor Lasers and Tailored Nanostructures for Raman Spectroscopy
This work presents the application of organic semiconductor distributed feedback laser as free-space excitation source in Raman spectroscopy. Surface-enhanced Raman scattering effect is exploited to improve the detection sensitivity. The SERS…
Organic Service-Level Management in Service-Oriented Environments
Dynamic service-oriented environments (SOEs) are characterised by a large number of heterogeneous service components that are expected to support the business as a whole. The present work provides a negotiation-based approach to facilitate automated…
Photonic crystal slabs for low-cost biosensors
Biosensors are devices that utilize biological recognition elements to selectively detect and analyze specific biological and chemical analyte substances. In this work a technology platform for label-free optical biosensors based on…
Planning the Charging Infrastructure for Electric Vehicles in Cities and Regions
Planning the charging infrastructure for electric vehicles (EVs) is a new challenging task. This book treats all involved aspects: charging technologies and norms, interactions with the electricity system, electrical installation, demand for charging…
Process Simulation of Technical Precipitation Processes - The Influence of Mixing
This work develops and shows up methods to tackle multi-scale challenges in particle formation during precipitation crystallization. Firstly, molecular, micro- and meso-scale interactions in confined impinging jet mixers are investigated and…
Production cost models with regard to liberalised electricity markets
This book makes a contribution to the formulation and implementation of production cost models for the modelling of liberalized electricity markets by addressing issues associated with the level of detail in the representation of the underlying power…
Production process design using Multi-Criteria Analysis
Intra- and inter-company production networks have gained increased importance in developed and industrialising countries. By reusing waste of industrial sites as a valuable input within the production network, material cycles can be closed and…
Reactive Control of Turbulent Wall-Bounded Flows for Skin Friction Drag Reduction
The work presents an attempt to improve the understanding of reactive drag reducing control of near-wall turbulence with respect to limitations present in a realistic application scenario. The reference reactive control scheme of opposition control…
Real-time Digital Signal Processing for Software-defined Optical Transmitters and Receivers
A software-defined optical Tx is designed and demonstrated generating signals with various formats and pulse-shapes in real-time. Special pulse-shapes such as OFDM or Nyquist signaling were utilized resulting in a highly efficient usage of the…
Role and dynamics of 'Late-comers' in the global technology competition
Faster developing cycles and economic developments created many emerging economies in the 20th century. For sustainable economic growth, however, the construction and constant preservation of a profound knowledge base and technological pool is…
The role of indicators in decisions of technology innovation
There are thousands of indicators produced to understand and govern our societies. Studies about the way indicators are used in technological innovation are significantly rare, despite the centrality of these decisions to promote growth in our…
Semantic Business Process Modeling
This book presents a process-oriented business modeling framework based on semantic technologies. The framework consists of modeling languages, methods, and tools that allow for semantic modeling of business motivation, business policies and rules,…
Soft Magnetic Composites in Novel Designs of Electrical Traction Machines
Nowadays, the manufacturing of electrical machines based on electrical steel laminations has been well established worldwide. Compared with the electrical steel, the soft magnetic composites (SMC) shows magnetic isotropy and lower eddy current…
Stability of cooperation in the international climate negotiations - An analysis using cooperative game theory
International cooperation on greenhouse gas emission reductions is needed to avoid dangerous climate change. This work analyses the stability of global cooperation on climate change using cooperative game theory. Numerical and theoretical models are…
Sulfur-tolerant natural gas reforming for fuel-cell applications
An attractive simplification of PEM-FC systems operated with natural gas would be the use of a sulfur tolerant reforming catalyst, but such a catalyst has not been available thus far. In this work it is demonstrated that a tailor made rhodium…
Surface wave driven molecular low pressure plasmas for general lighting
Nowadays, compact fluorescent lamps are widely-used in general lighting applications. However, they still struggle with acceptance problems due to the hazardous mercury, which serves as the radiant component inside the lamp. The presented work deals…
Timber Engineering - Principles for Design
This comprehensive book provides in-depth knowledge and understanding of design rules according to Eurocode 5. It is based on the first edition of the STEP (Structural Timber Education Programme) series, which was prepared in 1995 by about 50 authors…
Tracking Extended Objects in Noisy Point Clouds with Application in Telepresence Systems
We discuss theory and application of extended object tracking. This task is challenging as sensor noise prevents a correct association of the measurements to their sources on the object, the shape itself might be unknown a priori, and due to…
Transient behaviour of ITER poloidal field coils
Transient voltages occur on the terminals of superconducting coils and may lead to internal over-voltages. The main objective of this work was to calculate the transient electrical behaviour and internal voltage distribution within the ITER poloidal…
Tunable Diode-Laser Absorption Spectroscopy for Trace-Gas Measurements with High Sensitivity and Low Drift
This book discusses the mechanical and opto-electronic design of laser spectrometers for measuring two very important atmospheric gases, namely water vapor and its isotopic ratios, and formaldehyde. For measuring water vapor, shot-noise limited…
Turbulent open channel flow, sediment erosion and sediment transport
This thesis aims to contribute to a better understanding of turbulent open channel flow, sediment erosion and sediment transport. The thesis provides an analysis of high-fidelity data from direct numerical simulation of (i) open channel flow over an…
Two-Scale Thermomechanical Simulation of Hot Stamping
Hot stamping is a hot drawing process which takes advantage of the polymorphic steel behavior to produce parts with a good strength-to-weight ratio. For the simulation of the hot stamping process, a nonlinear two-scale thermomechanical model is…
Uncertainty handling in multi-attribute decision support for industrial risk management
The complexity of today's industrial production networks constitutes a new challenge for industrial risk and safety management. In order to handle potential risks to and emanating from industry and their respective impact on mankind as well as the…
Usage Policies for Decentralised Information Processing
Owners impose usage restrictions on their information, which can be based e.g. on privacy laws, copyright law or social conventions. Often, information is processed in complex constellations without central control. In this work, we introduce…
Web-oriented Event Processing
How can the Web be made situation-aware? Event processing is a suitable technology for gaining the necessary real-time results. The Web, however, has many users and many application domains. Thus, we developed multi-schema friendly data models…
Methods and Concepts for Designing and Validating Smart Grid Systems
Energy efficiency and low-carbon technologies are key contributors to curtailing the emission of greenhouse gases that continue to cause global warming. The efforts to reduce greenhouse gas emissions also strongly affect electrical power systems.…
Micro/Nano Materials for Clean Energy and Environment
The research center serves as a platform for researchers at both universities to conduct joint research in the targeted areas, and to meet regularly for information exchange, talent exchange, and knowledge mobilization, especially in the fields of…
Micro/Nano-Chip Electrokinetics
Micro/nanofluidic chips have found increasing applications in the analysis of chemical and biological samples over the past two decades. Electrokinetics has become the method of choice in these micro/nano-chips for transporting, manipulating and…
Microbial Community Modeling: Prediction of Microbial Interactions and Community Dynamics
It has the potential to resolve many issues in the realms of energy, food, human health, the environment, and biotechnology. Scientists are trying to understand, in a fundamental way, how microbes influence each other and how they organize into…
Microfluidics for Cells and Other Organisms
Microfluidics-based devices play an important role in creating realistic microenvironments in which cell cultures can thrive. They can, for example, be used to monitor drug toxicity and perform medical diagnostics, and be in a static-, perfusion- or…
Microscale Surface Tension and Its Applications
Building on advances in miniaturization and soft matter, surface tension effects are a major key to the development of soft/fluidic microrobotics. Benefiting from scaling laws, surface tension and capillary effects can enable sensing, actuation,…
Microstructure and Mechanical Properties of Structural Metals and Alloys
The papers collected in this special issue clearly reflect the modern research trends in materials science. These fields of specific attention are high-Mn TWIP steels, high-Cr heat resistant steels, aluminum alloys, ultrafine grained materials…
Mineralogy of Quartz and Silica Minerals
The present book reports recent contributions from research in the field of quartz and other silica minerals. The various forms of silica (SiO2) represent important constituents of the Earth crust and play a central role in the composition of…
Mitochondrial Dysfunction in Ageing and Diseases
The past decade has witnessed an explosion of knowledge regarding how mitochondrial dysfunction may translate into ageing and disease phenotypes, as well as how it is modulated by genetic and lifestyle factors. Impairment of the mitochondria may be…
Mobile Mapping Technologies
Mobile Mapping technologies have seen a rapid growth of research activity and interest in the last years, due to the increased demand of accurate, dense and geo-referenced 3D data. Their main characteristic is the ability of acquiring 3D information…
Modeling and Practice of Erosion and Sediment Transport under Change
Climate and anthropogenic changes impact the conditions of erosion and sediment transport in rivers. Rainfall variability and, in many places, the increase of rainfall intensity have a direct impact on rainfall erosivity. Increasing changes in…
Modeling and Simulation of Energy Systems
Energy Systems Engineering is one of the most exciting and fastest growing fields in engineering. Modeling and simulation plays a key role in Energy Systems Engineering because it is the primary basis on which energy system design, control,…
Modern Grinding Technology and Systems
This specialist edition features key innovations in the science and engineering of new grinding processes, abrasives, tools, machines, and systems for a range of important industrial applications. Topics written by invited, internationally recognized…
The Molecular and Cellular Basis for Parkinson's Disease
The focus on dopamine-sensitive motor symptoms, in association with the improvement of motor complications in the heterogeneous disease entity Parkinson's disease, has led to a certain standstill in research. This Special Issue provides new concepts…
Molecular Basis of Cardiovascular Diseases: Implications of Natriuretic Peptides
The natriuretic peptides (NPs) family includes a class of hormones and their receptors needed for the physiological control of cardiovascular functions. The discovery of NPs provided a fundamental contribution into our understanding of the…
Molecular Magnetism of Lanthanides Complexes and Networks
Over the last ten years a fresh air has been blowing in the field of molecular magnetism with the re-introduction of lanthanides ions as spin carriers in magnetic molecules. The strong magnetic moment and huge magnetic anisotropy of lanthanide ions…
Molecular Pharmacology and Pathology of Strokes
Stroke, a progressively non-communicable disease, is the second leading cause of death after coronary heart disease in developed countries. The present treatment options for stroke are adapting lifestyle practices, diabetes treatment, drugs, and the…
Molecular Science for Drug Development and Biomedicine
With the avalanche of biological sequences generated in the postgenomic age, molecular science is facing an unprecedented challenge, i.e., how to timely utilize the huge amount of data to benefit human beings. Stimulated by such a challenge, a rapid…
Multifunctional Oxide-Based Materials: From Synthesis to Application
The book deals with novel aspects and perspectives in metal oxide and hybrid material fabrication.
Multiscale and Innovative Kinetic Approaches in Heterogeneous Catalysis
Kinetics and reactor modeling for heterogeneous catalytic reactions are prominent tools for investigating and understanding catalyst functionalities at nanoscale and the related rates of complex reaction networks. This book illustrates some examples…
Nanoelectronic Materials, Devices and Modeling
As CMOS scaling is approaching the fundamental physical limits, a wide range of new nanoelectronic materials and devices have been proposed and explored to extend and/or replace the current electronic devices and circuits so as to maintain progress…
Nanogrids, Microgrids, and the Internet of Things (IoT): Towards the Digital Energy Network
Driven by new regulations, new market structures, and new energy resources, the smart grid has been the trigger for profound changes in the way that electricity is generated, distributed, managed, and consumed. The smart grid has raised the…
Nanostructure Based Sensors for Gas Sensing: from Devices to Systems
The development of solid state gas sensors based on microtransducers and nanostructured sensing materials is the key point in the design of portable measurement systems able to reach sensing and identification performance comparable with analytical…
Natural Compounds as New Cancer Treatments
Cancer remains one of the main causes of morbidity and mortality worldwide. Although many pharmacological and clinical advances have been made, there is a constant need for new molecules to improve the overall options for treatment. Natural compounds…
Natural Products for Cancer Prevention and Therapy
This Special Issue book, “Natural Products for Cancer Prevention and Therapy”, is based on recent advances in natural products for cancer prevention and therapy. For this purpose, the authors of this book have been organizing a biennial international…
Neglected and Emerging Tropical Diseases in South and Southeast Asia and Northern Australia
This Special Issue focuses on recent research on the important emerging and neglected tropical diseases (NTDs) in South and South East Asia and Northern Australia. This region stretches from Afghanistan in the west to Papua New Guinea in the east,…
New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases: Lessons from the Past and Future Challenges
This book illustrates some of the most recent research efforts that have been made in lowering plasma cholesterol levels in patients with CVD. Selected articles aimed to illuminate advances and urgent challenges in the management of CVD, including…
Noise and Vibration Control in the Built Environment
With global urbanization rapidly rising and the increasing need of high-quality built environments, the requirement of achieving improved sound quality, both for outdoor and indoor environments, has received a lot of attention. This Special Issue…
Non-destructive Testing of Materials in Civil Engineering
This book was proposed and organized as a means to present recent developments in the field of nondestructive testing of materials in civil engineering. For this reason, the articles highlighted in this editorial relate to different aspects of…
Novel Advances in Aquatic Vegetation Monitoring in Ocean, Lakes and Rivers
In recent decades, there has been an increase in the development of strategies for water ecosystem mapping and monitoring. Overall, this is primarily due to legislative efforts to improve the quality of water bodies and oceans. Remote sensing has…
Novel Biocomposite Engineering and Bio-Applications
The engineering and utilization of biocomposites is a research field of major scientific and industrial interest worldwide. The biocomposite area is extensive and spans from structured and solid biocomposites (e.g., reinforced bioabsorbable…
Novel Insights into Orbital Angular Momentum Beams: From Fundamentals, Devices to Applications
It is well-known by now that the angular momentum carried by elementary particles can be categorized as spin angular momentum (SAM) and orbital angular momentum (OAM). In the early 1900s, Poynting recognized that a particle, such as a photon, can…
Novel Pharmacological Inhibitors for Bacterial Protein Toxins
Many medically relevant bacteria cause severe human and animal diseases because they produce and release protein toxins that target mammalian cells. Because the toxin-induced cell damage is the reason for the clinical symptoms, the targeted…
Numerical and Evolutionary Optimization
This book was established after the 6th International Workshop on Numerical and Evolutionary Optimization (NEO), representing a collection of papers on the intersection of the two research areas covered at this workshop: numerical optimization and…
Nutraceuticals and the Skin: Roles in Health and Disease
he skin is the largest organ of the body and serves as a barrier between the inner and external environments. As such, any problems in the skin can have serious effects on systemic health and well-being. Several studies have established that both…
Nutrients in Infancy
Infants are not just small adults; they have a complex set of nutrient requirements and interactions to account for the high metabolic rate, growth, immunological and cognitive development, etc. Each year there are 138 million births, including 30…
Nutrients, Infectious and Inflammatory Diseases
Foodborne disease like salmonellosis and toxoplasmosis are amongst the most significant causes of hospitalization in the U.S. and globally. Gastrointestinal infections alter gut microbiomes and increase permeability to toxins. Various invasions by…
Nutrition and Allergic Diseases
The purpose of this Special Issue, “Nutrition and Allergic Diseases”, is to provide an overview of the role of nutrition in allergy. The prevalence of asthma, rhinitis, and food allergy has increased tremendously over the last few decades. Is there a…
Nutrition and Liver Disease
Malnutrition in people with liver disease is a challenging issue due to its multifactorial nature, which includes hypermetabolism, increased energy needs, malabsorption, and anorexia. Despite advances in both assessment and management, correct…
Nutrition in Pregnancy - Volume II
Maternal nutrition during pregnancy is of considerable interest to women, their partners and their health care professionals. In developing countries, maternal undernutrition is a major concern. However, with the increased prevalence of abundant high…
Nutrition in Pregnancy: Volume I
Maternal nutrition during pregnancy is of considerable interest to women, their partners and their health care professionals. In developing countries, maternal undernutrition is a major concern. However, with the increased prevalence of abundant high…
One Health and Zoonoses
The One Health concept recognizes that the health of humans, animals, and their ecosystems are interconnected, and that a coordinated, collaborative, multidisciplinary, and cross-sectoral approach is necessary to fully understand and respond to…
Open-Source Electronics Platforms
Open-source electronics are becoming very popular, and are integrated with our daily educational and developmental activities. At present, the use open-source electronics for teaching science, technology, engineering, and mathematics (STEM) has…
Optics and Spectroscopy for Fluid Characterization
All over the world, there is a huge and ever-increasing interest in the development and application of optical and spectroscopic techniques to characterize fluids in engineering and science. The large number of review articles that are frequently…
Optimisation Models and Methods in Energy Systems
Challenging problems arise in all segments of energy industries—generation, transmission, distribution and consumption. Optimization models and methods play a key role in offering decision/policy makers better information to assist them in making…
Physical Metallurgy of High Manganese Steels
The Special Issue ‘Physical Metallurgy of High Manganese Steels’ addresses the highly fascinating class of manganese-alloyed steels with manganese contents well above 3 mass%. The book gathers manuscripts from internationally recognized researchers…
Physiological Responses to Abiotic and Biotic Stress in Forest Trees
As sessile organisms, plants have to cope with a multitude of natural and anthropogenic forms of stress in their environment. Due to their longevity, this is of particular significance for trees. As a consequence, trees develop an orchestra of…
Planning, Development and Management of Sustainable Cities
The concept of ‘sustainable urban development’ has been pushed to the forefront of policymaking and politics as the world wakes up to the impacts of climate change and the destructive effects of the Anthropocene. Climate change has emerged to be one…
Plant Medicines for Clinical Trial
Plant medicines are the original medicines that humans have always used. Many people continue to use plant medicines today including teas, coffee, chocolate, ginger, and other medicines. Traditional medicine is based on plant medicines and is the…
Plant Natural Products for Human Health
Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as…
Plant Nutrient Dynamics in Stressful Environments
The papers included in this special issue cover a broad range of aspects ranging from genetics and breeding to crop production in the field. Climate change, intensified agriculture, modifications of land use, or pollution are often accompanied by…
Plasma Catalysis
Plasma catalysis is gaining increasing interest for various gas conversion applications, such as CO2 conversion into value-added chemicals and fuels, N2 fixation for the synthesis of NH3 or NOx, methane conversion into higher hydrocarbons or…
Plasma Processes for Renewable Energy Technologies
The use of renewable energy is an effective solution for the prevention of global warming. On the other hand, environmental plasmas are one of powerful means to solve global environmental problems on nitrogen oxides, (NOx), sulfur oxides (SOx),…
Plasmonics and its Applications
Plasmonics is a rapidly developing field that combines fundamental research and applications ranging from areas such as physics to engineering, chemistry, biology, medicine, food sciences, and the environmental sciences. Plasmonics appeared in the…
Polarimetric SAR Techniques and Applications
Polarimetry allows sensitivity to the structural and geometric properties of the scene, making it possible a more accurate identification and classification than non-polarimetric systems. Then, polarimetry makes possible new applications, especially…
Polyamine Metabolism in Disease and Polyamine-Targeted Therapies
Polyamines are ubiquitous polycations essential for all cellular life. The most common polyamines in eukaryotes, spermine, spermidine, and putrescine, exist in millimolar intracellular concentrations that are tightly regulated through biosynthesis,…
Roles of NF-κB in Cancer and Their Therapeutic Approaches
Although mortality rates have declined in recent years, the majority of cancers are still difficult to treat and the medical need for better cancer treatment is evident. The current anticancer armamentarium includes many active agents that are…
Selected Problems in Fluid Flow and Heat Transfer
Fluid flow and heat transfer processes play an important role in many areas of science and engineering, from the planetary scale (e.g., influencing weather and climate) to the microscopic scales of enhancing heat transfer by the use of nanofluids;…
Sensors in Agriculture
Agriculture requires technical solutions for increasing production while lessening environmental impact by reducing the application of agro-chemicals and increasing the use of environmentally friendly management practices. A benefit of this is the…
Sensors in Agriculture
Agriculture requires technical solutions for increasing production while lessening environmental impact by reducing the application of agro-chemicals and increasing the use of environmentally friendly management practices. A benefit of this is the…
Short Rotation Woody Crop Production Systems for Ecosystem Services and Phytotechnologies
While international efforts in the development of short rotation woody crops (SRWCs) have historically focused on the production of biomass for bioenergy, biofuels, and bioproducts, research and deployment over the past decade has expanded to include…
Silicon-Based Nanomaterials: Technology and Applications
Silicon has been proven to be remarkably resilient as a commercial electronic material. The microelectronics industry has harnessed nanotechnology to continually push the performance limits of silicon devices and integrated circuits. Rather than…
Smart machines, Remote Sensing, Precision Farming, Processes, Mechatronic, Materials and Policies for Safety and Health Aspects
The introduction of "smart machines" for agricultural operations will allow several advantages, such as an increase in their efficiencies, a reduction in environmental impacts and a reduction of work injuries. There are partially- and fully-automatic…
Smart Sensors for Structural Health Monitoring
Smart sensors are technologies designed to facilitate the monitoring operations. For instance, power consumption can be minimized through on-board processing and smart interrogation algorithms, and state detection enhanced through collaboration…
Smart Textiles Production: Overview of Materials, Sensor and Production Technologies for Industrial Smart Textiles
The research field of smart textiles is currently witnessing a rapidly growing number of applications integrating intelligent functions in textile substrates. With an increasing amount of new developed product prototypes, the number of materials used…
Smart Sustainable Manufacturing Systems
With the advent of disruptive digital technologies, companies are facing unprecedented challenges and opportunities. Advanced manufacturing systems are of paramount importance in making key enabling technologies and new products more competitive,…
Soil Water Conservation. Dynamics and Impact
Human needs like food and clean water are directly related to good maintenance of healthy and productive soils. A good understanding of human impact on the natural environment is therefore necessary to preserve and manage soil and water resources.…
Solar Energy Applications in Houses, Smart Cities and Microgrids
Five papers were selected for this Special Issue, with three relating to solar energy applications in houses, smart cities, and microgrids; one studying the relationship between the smart city model and the concept of energy sustainability; and one…
Structural Health Monitoring (SHM) of Civil Structures
Deficiencies in these areas may be remediated by advancements in structural health monitoring (SHM) technologies that provide sensing systems to automatically and economically diagnose structural integrity. In a sense, SHM technologies will help pave…
Structure and Mechanical Properties of Transition Group Metals, Alloys, and Intermetallic Compounds
The aim of this Special Issue is to present the latest theoretical and experimental achievements concerning the mechanisms of microstructural change in metallic materials subject to different processing methods, and their effect on mechanical…
Sustainability in Construction Engineering
The concept of sustainability has been expanding to all areas of economic activity, including construction. The Special Issue “Sustainability in Construction Engineering” provided a possibility for researchers to disseminate their new ideas and…
Sustainable Agriculture–Beyond Organic Farming
The current conception of organic farming is the result of nearly a century of intellectual thought and dialogue, field observations and experiences, systematic experimentation, and codification of rules. Debates on the future viability of organic…
Sustainable Business Models
The dynamically changing world economy, in an era of intensive development and globalization, creates new needs in both the theoretical models of management and in the practical discussion related to the perception of business. Because of new…
Sustainable Consumer Behavior
The dynamically changing world economy, in an era of intensive development and globalization, creates new needs in both the theoretical models of management and in the practical discussion related to the perception of business. Because of new…
Sustainable Freight Transport
This Special Issue of Sustainability reports on recent research aiming to make the freight transport sector more sustainable. The sector faces significant challenges in different domains of sustainability, including the reduction of greenhouse gas…
Sustainable Human Resource Management
The concept of sustainability is important for companies both in the case of SMEs and worldwide multinational companies. Some key factors to help a company achieve its sustainability objectives are based on human resource management. Sustainable…
Sustainable Territorial Management
Human development has made remarkable social and economic progress possible for most of us but has also entailed a range of serious impacts on natural resources, local communities and the economy at multiple scales. Thus, achieving sustainable…
Symmetry in Engineering Sciences
This book presents interesting samples of theoretical and practical advances of symmetry in multidisciplinary engineering applications. It covers several applications, such as accessibility and traffic congestion management, path planning for mobile…
Teenage Reproductive Health: Pregnancy, Contraception, Unsafe Abortion, Fertility
Maternal mortality is still globally high and reducing it is a top priority. Teenage pregnancies have more complications and are also unwanted in many cases. This contributes to the high maternal mortality with both obstetric complications and burden…
Thermal and Electro-thermal System Simulation
With increasing power levels and power densities in electronics systems, thermal issues are becoming more and more critical. The elevated temperatures result in changing electrical system parameters, changing the operation of devices, and sometimes…
Thin Films for Energy Harvesting, Conversion, and Storage
Efficient clean energy harvesting, conversion, and storage technologies are of immense importance for the sustainable development of human society. To this end, scientists have made significant advances in recent years regarding new materials and…
Tissue Engineering and Regenerative Nanomedicine
This book focus on the most recent advances related to the design and processing methods of different nanobiomaterials, films, and fibers; surface functionalization strategies, including biological performance assessment and cytocompatibility; and…
Toward a Sustainable Agriculture: Farming Practices and Water Use
Globally, the agri-food sector has a major role to play in ensuring food security and economic development, especially for lower income countries. In the increasingly demanding context of environmental risk, exacerbated by climate change, and of…
Towards Sustainable Global Food Systems. Conceptual and Policy Analysis of Agriculture, Food and Environment Linkages
One of the major knowledge challenges in the domain of Resilient and Sustainable Food Systems refers to the integration of perspectives on consumption, patterns that support public health, inclusive value chains, and environmentally sustainable food…
Toxins in Drug Discovery and Pharmacology
Venoms from marine and terrestrial animals (cone snails, scorpions, spiders, snakes, centipedes, cnidarian, etc.) can be seen as untapped cocktails of biologically active compounds that are being increasingly recognized as a new emerging source of…
Traditional and Innovative Approaches in Seismic Design
This special issue collects selected papers about a wide range of innovative applications in earthquake engineering. These studies were presented during the 2nd Edition of the International Workshop “Traditional and Innovative Approaches in Seismic…
Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts
The year 2017 marks the 20th anniversary of the molecular cloning of the long sought-after capsaicin receptor, now known as TRPV1 (Transient Receptor Potential Vanilloid 1). This seminal discovery has opened up a “hot” new field of basic research and…
Transmucosal Absorption Enhancers in the Drug Delivery Field
Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery…
Transport of Fluids in Nanoporous Materials
Fluid transport in narrow pores is central to the design and optimization of nanoporous materials in industrial applications, such as catalysis, nanofluids, electrochemical batteries, and membrane separation. However, due to the strong potential…
Travel Medicine - Series 1
This collection of papers describes the recent development of travel health and vaccination services delivered by pharmacists. It is the first dedicated collection of its type and provides a template for the continued growth of pharmacy practice in…
Trends in Catalytic Wet Peroxide Oxidation Processes
This book gives an overview of the state of the art in Catalytic Wet Peroxide Oxidation research for the treatment of industrial and urban wastewaters and provides novel solutions to overcome the current challenges of this technology. These solutions…
Tribological Performance of Artificial Joints
Joint replacement is a very successful medical treatment. However, the survivorship of the implants could be adversely affected due to the loss of materials in the form of particles or ions as the bearing surfaces articulate against earch other. The…
Tribology and Surface Engineering
The Special Issue on Tribology and Surface Engineering includes nine research articles
and one review article. It concerns a very important problem of resistance to wear and shaping the
properties of the surface layers of different materials by…
and one review article. It concerns a very important problem of resistance to wear and shaping the
properties of the surface layers of different materials by…
TRP Channels in Health and Disease
Almost 25 years ago, the first mammalian transient receptor potential (TRP) channel was cloned and published. TRP channels now represent an extended family of 28 members fulfilling multiple roles in the living organism. Identified functions include…
The Tumor Microenvironment of High Grade Serous Ovarian Cancer
The Special Issue on high grade serous ovarian cancer (HGSOC) and the contribution of the tumor microenviroment (TME) consists of reviews contributed by leaders in the OC field. As HGSOC metastases have a highly complex TME, there is an urgent need…
Turbulence in River and Maritime Hydraulics
Understanding of the role of turbulence in controlling transport processes is of paramount importance for the preservation and protection of aquatic ecosystems, the minimization of the deleterious consequences of anthropogenic activity, and the…
Two-Dimensional Electronics - Prospects and Challenges
The first two-dimensional material studied in detail was graphene, and many groups explored its potential for electronic applications. Meanwhile, researchers have extended their work to two-dimensional materials beyond graphene. At present, several…
Nursing Pharmacology
This open access Nursing Pharmacology textbook is designed for entry-level undergraduate nursing students. It explains basic concepts of pharmacology and describes common medication classes. This book is not intended to be used as a drug reference…
Strategic Management
This open source textbook is derived from many sources, initially from the Principles of Management by Carpenter, Bauer, and Erdogan, but there is abundant new content as well. It is published under a Creative Commons license and as such there is no…
AC Electrical Circuit Analysis: A Practical Approach
theory and practical application of analysis of AC electrical circuits. It assumes familiarity with DC circuit analysis. If you have not studied DC circuit analysis, it is strongly recommended that you read the companion OER text, DC Electrical…
DC Electrical Circuit Analysis: A Practical Approach
elcome to DC Electrical Circuit Analysis, an open educational resource (OER). The goal of this text is to introduce the theory and practical application of analysis of DC electrical circuits. It is offered free of charge under a Creative Commons…
Introduction to Industrial Engineering
This book was created for an undergraduate Introduction to Industrial Engineering course at The University of Texas at Arlington (UTA). The chapters give an overview of the profession and an introduction to some of the tools used by industrial…
Large Animal Surgery – Supplemental Notes
This textbook includes basic principles of large animal surgery and anesthesia, how to apply those principles to cases and situations, and discover ways of finding answers when you don’t remember the information, are presented with cases that aren’t…
Financial Management for Small Businesses: Financial Statements & Present Value Models
This book is for those whose financial management focus is on small businesses. For you, we adapt the traditional financial management themes emphasized in corporate financial management courses to meet the needs of small businesses.
Many…
Many…
Adaptive Strategies for Water Heritage
This Open Access book, building on research initiated by scholars from the Leiden-Delft-Erasmus Centre for Global Heritage and Development (CHGD) and ICOMOS Netherlands, presents multidisciplinary research that connects water to heritage. Through…
Advances in Crowdfunding
This open access book presents a comprehensive and up-to-date collection of knowledge on the state of crowdfunding research and practice. It considers crowdfunding models and their different manifestations across a variety of geographies and sectors,…
Advances in Energy System Optimization
The papers presented in this open access book address diverse challenges in decarbonizing energy systems, ranging from operational to investment planning problems, from market economics to technical and environmental considerations, from distribution…
Advances in Pharma Business Management and Research
This open access book presents a unique collection of practical examples from the field of pharma business management and research. It covers a wide range of topics such as: 'Brexit and its Impact on pharmaceutical Law - Implications for Global…
Advances in Production Technology
This edited volume contains the selected papers presented at the scientific board meeting of the German Cluster of Excellence on “Integrative Production Technology for High-Wage Countries”, held in November 2014. The topical structure of the book is…
Perspectives on European Earthquake Engineering and Seismology: Volume 1
This book collects 5 keynote and 15 topic lectures presented at the 2nd European Conference on Earthquake Engineering and Seismology (2ECEES), held in Istanbul, Turkey, from August 24 to 29, 2014. The conference was organized by the Turkish…
Advancing the Science of Cancer in Latinos
This open access book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the…
Achieving the Paris Climate Agreement Goals
This open access book presents detailed pathways to achieve 100% renewable energy by 2050, globally and across ten geographical regions. Based on state-of-the-art scenario modelling, it provides the vital missing link between renewable energy targets…
Advancing Culture of Living with Landslides: Volume 1 ISDR-ICL Sendai Partnerships 2015-2025
This volume contains peer-reviewed papers from the Fourth World Landslide Forum organized by the International Consortium on Landslides (ICL), the Global Promotion Committee of the International Programme on Landslides (IPL), University of Ljubljana…
Agricultural Implications of the Fukushima Nuclear Accident (III)
This open access book presents the findings from on-site research into radioactive cesium contamination in various agricultural systems affected by the Fukushima Daiichi Nuclear Power Plant accident in March 2011. This third volume in the series…
AiREAS: Sustainocracy for a Healthy City
This book describes the coming about and first results of the AiREAS "healthy city" cooperative in the city of Eindhoven and Province of North Brabant in the Netherlands. AiREAS is an initiative focused on the multidisciplinary co-creation of healthy…
Animals and the Shaping of Modern Medicine
This book breaks new ground by situating animals and their diseases at the very heart of modern medicine. In demonstrating their historical significance as subjects and shapers of medicine, it offers important insights into past animal lives, and…
The Art of Sustainable Performance
This open access book revisits common notions on how to select and recruit the right employees. It reveals that the secret of successful individuals and teams lies in a combination of talent and four important performance indicators, offering an…
Belly-Rippers, Surgical Innovation and the Ovariotomy Controversy
This open access book looks at the dramatic history of ovariotomy, an operation to remove ovarian tumours first practiced in the early nineteenth century. Bold and daring, surgeons who performed it claimed to be initiating a new era of surgery by…
Biofuels and Sustainability
This open access book presents a comprehensive analysis of biofuel use strategies from an interdisciplinary perspective using sustainability science. This interdisciplinary perspective (social science-natural science) means that the strategies and…
Bioimage Data Analysis Workflows
This Open Access textbook provides students and researchers in the life sciences with essential practical information on how to quantitatively analyze data images. It refrains from focusing on theory, and instead uses practical examples and step-by…
The Discipline of Organizing: 4th Professional Edition
We organize things, we organize information, we organize information about things, and we organize information about information. But even though “organizing” is a fundamental and ubiquitous challenge, when we compare these activities their contrasts…
Parenting and Family Diversity Issues
This book has been created for students and all individuals who work with children and families (e.g., educators, parents, caregivers, direct support workers, etc.) in diverse contexts. It is imperative to understand how and what factors may…
Brain and Human Body Modeling
This open access book describes modern applications of computational human modeling with specific emphasis in the areas of neurology and neuroelectromagnetics, depression and cancer treatments, radio-frequency studies and wireless communications.…
Brain and Human Body Modeling 2020
This open access book describes modern applications of computational human modeling in an effort to advance neurology, cancer treatment, and radio-frequency studies including regulatory, safety, and wireless communication fields. Readers working on…
Buruli Ulcer
A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into…
Charting Spiritual Care
This open access volume is the first academic book on the controversial issue of including spiritual care in integrated electronic medical records (EMR). Based on an international study group comprising researchers from Europe (The Netherlands,…
Blockchain and Crypto Currency
This open access book contributes to the creation of a cyber ecosystem supported by blockchain technology in which technology and people can coexist in harmony. Blockchains have shown that trusted records, or ledgers, of permanent data can be stored…