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                <text>In pregnancy, maternal nutrition sustains and nourishes the developing child. Imbalances in either the direction of nutritional excess or deficiency can have adverse consequences for child health. In addition, more research now suggests that good pregnancy nutrition influences child health beyond pregnancy and delivery. This includes modifying the risk of child health outcomes as they enter childhood and adulthood through influences on placental development, hormonal pathways, and organ structure and function. Poor pregnancy nutrition may also compromise maternal health during pregnancy, which may have long-term consequences for women’s health.</text>
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                <text>Maslova, Ekaterina</text>
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                <text>Plant genetic resources for food and agriculture (PGRFA) have been collected and exchanged for centuries. The rapid development of novel tools for genetic and phenotypic analysis is changing the way we can uncover diversity and exploit its value in modern agriculture. The integration of novel analytical tools is crucial for translating research into much-needed, more efficient management and use of PGRFA. This Special Issue provides an overview of recent topics on plant genetics and biotechnology in biodiversity.</text>
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                <text>Rosa Rao (Ed.) --- Giandomenico Corrado (Ed.)</text>
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                <text>Currently, in the cosmetic industry, there is an increasing interest in natural extracts, particularly plant extracts. The inclusion of antioxidants in topical formulations may contribute to minimize skin oxidative stress, which has been associated with aging. Many herbal agents used in cosmetics have been selected by a process of ‘trial and error’ and, thus, are used on the basis of experience rather than of experimental investigation. Nevertheless, there is now a growing scientific evidence that plants possess a vast and complex arsenal of active ingredients able not only to calm or smooth but also to actively restore, heal, and protect the human skin. </text>
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                <text>Beatriz P.P. Oliveira (Ed.) --- Francisca Rodrigues (Ed.)</text>
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                <text>Optimal nutrition is fundamental for enhancing training, recovery and performance in sport. Therefore, research has aimed to determine the efficacy of appropriate intake of nutrients, fluids, and supplements and their role in exercise performance. The purpose of this Special Issue entitled “Nutrition, Health and Athletic Performance” is to highlight recent research examining aspects of sports nutrition and exercise performance. Manuscript submissions of original research, meta-analyses, or reviews of the scientific literature, which targets nutritional strategies to benefit performance and health, are welcome. Studies performed in humans are preferred given the applied nature of this issue.</text>
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                <text> Kelly Pritchett (Ed.) --- Enette Larson Meyer (Ed.)</text>
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                <text>: The effect of germinated Superhongmi, a reddish brown pigmented rice cultivar, on the glucose profile and bone turnover in the postmenopausal-like model of ovariectomized rats was determined. The ovariectomized Sprague-Dawley rats were randomly divided into three dietary groups (n = 10): normal control diet (NC) and normal diet supplemented with non-germinated Superhongmi (SH) or germinated Superhongmi (GSH) rice powder. After eight weeks, the SH and GSH groups showed significantly lower body weight, glucose and insulin concentrations,&#13;
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                <text>The Gulf of Mexico is the ninth largest body of water in the world, and it is recognized as 1 of 64 Large Marine Ecosystems by the U.S. National Oceanic and Atmospheric Administration (NOAA) (Kumpf et al. 1999). Economically and ecologically the Gulf is one of the most productive and important bodies of water (Tunnell 2009; Fautin et al. 2010; NOS/NOAA 2011;&#13;
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                <text>The carotid body (CB) is the main arterial chemoreceptor in charge of adjusting ventilatory and cardiovascular function during changes in arterial blood gases. Regardless this essential function, the CB has been implicated in the sensing of other physiological signals such as changes in blood flow and glucose levels. More important, malfunction of the CB chemoreceptors has been associated with the progression and deterioration of several disease states such as hypertension, heart failure, renal failure, insulin resistance, diabetes and sleep apnea. Although the mechanisms involved in the alterations of the CB function in pathophysiology are currently under intense research, the development of therapeutic approaches to restore normal CB chemoreflex function remains unsolved.</text>
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                <text>Rodrigo Del Rio -, Rodrigo Iturriaga -, Harold D. Schultz</text>
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                <text> The present thesis deals with a deep analysis of the genetic structure of extant human worldwide populations, with a special focus on the Mediterranean. Different genetic markers, 18 Alu insertions and 367 single nucleotide polymorphisms (SNPs), were analysed for the first time in general populations and Bedouins from Jordan. The same SNPs were also genotyped in a consistent set of samples from the Mediterranean Basin. Specifically, Alu markers were used to assess the genetic diversity within Jordan and to define the relationships across present-day Middle Eastern, North African, and European populations. While SNPs located in the top coronary artery disease (CAD) risk regions (1p13, 1q41, 9p21, and 10q11) were used to explore the genetic variation and the LD patterns across 19 populations from Europe, Middle East and North Africa, together with Asian and African samples from the 1000 Genomes Project. Furthermore, Tunisian and Moroccan case-control samples were used to test for the first time the applicability of European GWAS results in these four genomic regions to North African populations. Finally, simulated genomic data were used to evaluate the consistency of association results across European, Asian and Sub-Saharan African case-control samples. Neutral and CAD risk markers pointed out a low but significant geographic structure in the Mediterranean area. As a particular case in the Mediterranean context, Bedouins and general population from Jordan showed statistical differences (p=0.038). The genetic heterogeneity detected is likely related to the fact that urban areas have been subject to several external influences but Bedouins have preserved their own genetic background because of their nomadic and isolated lifestyle. The general patterns of genetic variation observed in the four CAD risk regions analysed are in agreement with the genetic structure generated by demographic processes. Despite this fact, the present work also identified potential signals of positive and balancing selection in some specific risk markers and haplotypes. Actually, potential signatures of positive selection in the 9p21 region and of balancing selection in 9p21 and 10q11 have been observed. The regions under positive or balancing selection are shared across continents but the specific markers under selection are, in some cases, continent-specific. Results from the association study in North Africa revealed significant association signals in the four genomic regions analysed in Moroccan and Tunisian samples confirming the trans-ethnic importance of these genomic regions for the risk of CAD. However, in the meta-analyses performed with the North African case-control samples, only the 9p21 and 10q11 regions showed association signals and none of the North African risk SNPs was associated with CAD in Europe. These arguments suggest the existence of continent-specific CAD risk variants in these chromosomal regions. Significant differences in the LD and in the haplotype patterns confirm the heterogeneity in the genomic structure between North Africans and Europeans. In addition, differences in the LD structure persist even across Europeans, North Africans, Asians, and Sub-Saharan Africans. Finally, the simulation study highlighted an overall consistency in effect direction across populations of different ancestry, specially between Europeans and Asians. Because simulations assumed no actual differences in genetic effect size between populations and because the rate of between-population effect size differences generated by our study was considerably lower than the rate reported from empirical studies using real data, our study supports the existence of real differences in the genetic risk architecture of complex traits between populations. In general, this study confirmed that a substantial fraction of association signals are shared across people of different ancestries. However, some discrepancies in the effect size across populations highlighted the importance of accounting for population structure in association studies.</text>
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                <text>The book contains the substance of the lectures and partly of the practices of the subject of ‘Genetics and Genomics’ held in Semmelweis University for medical, pharmacological and dental students. The book does not contain basic genetics and molecular biology, but rather topics from human genetics mainly from medical point of views. Some of the 15 chapters deal with medical genetics, but the chapters also introduce to the basic knowledge of cell division, cytogenetics, epigenetics, developmental genetics, stem cell&#13;
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For free. For everyone. Forever. #YouCanLearnAnything&#13;
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MCAT on Khan Academy: Go ahead and practice some passage-based questions!&#13;
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About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content.&#13;
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For free. For everyone. Forever. #YouCanLearnAnything&#13;
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Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1&#13;
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Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/behavior/biological-basis-of-behavior-ner/v/modern-ways-of-studying-the-brain?utm_source=YT&amp;utm_medium=Desc&amp;utm_campaign=mcat&#13;
&#13;
MCAT on Khan Academy: Go ahead and practice some passage-based questions!&#13;
&#13;
About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content.&#13;
&#13;
For free. For everyone. Forever. #YouCanLearnAnything&#13;
&#13;
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The brain, however, appears to accumulate ischemic injury faster than any other organ. Without special treatment after circulation is restarted, full recovery of the brain after more than 3 minutes of clinical death at normal body temperature is rare. Usually brain damage or later brain death results after longer intervals of clinical death even if the heart is restarted and blood circulation is successfully restored. Brain injury is therefore the chief limiting factor for recovery from clinical death.&#13;
&#13;
Although loss of function is almost immediate, there is no specific duration of clinical death at which the non-functioning brain clearly dies. The most vulnerable cells in the brain, CA1 neurons of the hippocampus, are fatally injured by as little as 10 minutes without oxygen. However, the injured cells do not actually die until hours after resuscitation. This delayed death can be prevented in vitro by a simple drug treatment even after 20 minutes without oxygen. In other areas of the brain, viable human neurons have been recovered and grown in culture hours after clinical death. Brain failure after clinical death is now known to be due to a complex series of processes called reperfusion injury that occur after blood circulation has been restored, especially processes that interfere with blood circulation during the recovery period. Control of these processes is the subject of ongoing research.&#13;
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In 1990, the laboratory of resuscitation pioneer Peter Safar discovered that reducing body temperature by three degrees Celsius after restarting blood circulation could double the time window of recovery from clinical death without brain damage from 5 minutes to 10 minutes. This induced hypothermia technique is beginning to be used in emergency medicine. The combination of mildly reducing body temperature, reducing blood cell concentration, and increasing blood pressure after resuscitation was found especially effective—allowing for recovery of dogs after 12 minutes of clinical death at normal body temperature with practically no brain injury. The addition of a drug treatment protocol has been reported to allow recovery of dogs after 16 minutes of clinical death at normal body temperature with no lasting brain injury. Cooling treatment alone has permitted recovery after 17 minutes of clinical death at normal temperature, but with brain injury.&#13;
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Under laboratory conditions at normal body temperature, the longest period of clinical death of a cat (after complete circulatory arrest) survived with eventual return of brain function is one hour.....&#13;
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Input by Sofia Nelly</text>
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                <text>&lt;a href="http://creativecommons.org/licenses/by/3.0/legalcode"&gt;Creative Commons License&lt;/a&gt;&lt;br /&gt;This video represents licensed content on YouTube, meaning that the content has been claimed by a YouTube content partner.</text>
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